Animal Cells and Systems, 2022 Inhibition of cluster of differentiation 44 (CD44), a pancreatic cancer stem cell (CSC) marker, is a potential treatment for pancreatic ductal adenocarcinoma (PDAC). In this study, we evaluated the effect of 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG), a
Eun-Young Kim +2 more
doaj +1 more source
Journal of Pharmacological Sciences, 2021 Pentagalloylglucose (PGG), a gallotannin polyphenolic compound, has been found to possess a host of beneficial pharmacologic activities, such as anti-inflammatory and antioxidative activities.
Jinzhi Tong +9 more
doaj +1 more source
Comprehensive analysis of telomerase inhibition by gallotannin
Oncotarget, 2018 Gallotannin (or tannic acid) is a naturally occurring compound that inhibits cell growth and activity of different DNA-polymerases, including telomerase. The purpose of the present study was to gain insight into the mechanism of telomerase inhibition by gallotannin.
Savelyev, Nikita +5 more
openaire +3 more sources
The biological activities of roots and aerial parts of Alchemilla vulgaris L [PDF]
, 2018 The phytochemical composition, in vitro antioxidant and antimicrobial activities, cytotoxicity and antigenotoxicity of fruit extracts of Opuntia dillenii were studied.
BAUER, PASCAL ANDRE' +9 more
core +2 more sources
Protein foszfatázok szabályozása kölcsönható fehérjékkel = Regulation of protein phosphatases by protein-protein interactions [PDF]
, 2007 A pályázatban a miozin foszfatáz foszforilációval történő szabályozását és az enzim fehérje-fehérje kölcsönhatásait tanulmányoztuk. A holoenzimben protein foszfatáz-1 katalitikus alegység (PP1c) kapcsolódik a miozinhoz is kötődő szabályozó alegységhez ...
Csortos, Csilla +3 more
core
An overview of potential multipurpose agroforestry tree species, Syzygium cuminii (L.) Skeels in India [PDF]
, 2016 Jamun (Syzygium cuminii L.) Skeels) is evergreen MPTs (Multipurpose Tree species) widely grown in traditional agroforestry systems (agri-silviculture and agri-horticulture) of India, except very dry areas.
Bhalawe, S. +3 more
core +2 more sources
Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security
Journal of the Science of Food and Agriculture, EarlyView.Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori +9 more
wiley +1 more source
Gallotannin imposes S phase arrest in breast cancer cells and suppresses the growth of triple-negative tumors in vivo. [PDF]
PLoS ONE, 2014 Triple-negative breast cancers are associated with poor clinical outcomes and new therapeutic strategies are clearly needed. Gallotannin (Gltn) has been previously demonstrated to have potent anti-tumor properties against cholangiocarcinoma in mice, but ...
Tiejun Zhao +5 more
doaj +1 more source
A foszforilációs-defoszforilációs jelátviteli útvonalak kölcsönhatásai a szabad gyökök által kiváltott jelátviteli pályákkal = Cross-talk between phosphorylation-dephosphorylation and free radical-mediated signal transduction pathways [PDF]
, 2006 A peroxinitrit humán keratinocita (HaCaT) sejtekben intracelluláris kalcium mobilizációt okoz. Igazoltuk a kalcium mobilizáció szerepét mind az apoptotikus, mind a nekrotikus sejthalálban.
Bai, Péter +7 more
core
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source