Results 21 to 30 of about 6,064 (187)

Understanding the role of gamma delta (γδ) T cells in pancreatic cancer metastasis [PDF]

, 2022
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with a 1-year survival rate of 5.6% and a 10-year survival rate of
Lawrence, Mark
core   +1 more source

Augmenting human gamma delta lymphocytes for cancer therapy with chimeric antigen receptors

Exploration of Immunology, 2022
Gamma delta lymphocytes (γδ T) sit at the interface between innate and adaptive immunity. They have the capacity to recognize cancer cells by interaction of their surface receptors with an array of cancer cell surface target antigens.
Gabrielle M. Ferry, John Anderson
doaj   +1 more source

The protective role of tissue-resident interleukin 17A–producing gamma delta T cells in Mycobacterium leprae infection

Frontiers in Immunology, 2022
Mycobacterium leprae is a kind of disease-causing bacteria and results in leprosy in human. Gamma delta (γδ) T cell is a T-cell subset that is presented in both human dermis and epidermis.
Yan Liu, Chao Shi, Shanshan Ma, Yuelong Ma, Xinyuan Lu, Jianyu Zhu, Degang Yang   +6 more
doaj   +1 more source

Characterization of Adaptive-like γδ T Cells in Ugandan Infants during Primary Cytomegalovirus Infection

Viruses, 2021
Gamma-delta (γδ) T cells are unconventional T cells that help control cytomegalovirus (CMV) infection in adults. γδ T cells develop early in gestation, and a fetal public γδ T cell receptor (TCR) clonotype is detected in congenital CMV infections ...
Jessica Tuengel, Sanya Ranchal, Alexandra Maslova, Gurpreet Aulakh, Maria Papadopoulou, Sibyl Drissler, Bing Cai, Cetare Mohsenzadeh-Green, Hugo Soudeyns, Sara Mostafavi, Peter van den Elzen, David Vermijlen, Laura Cook, Soren Gantt   +13 more
doaj   +1 more source

Revisiting the Role of γδ T Cells in Anti-CMV Immune Response after Transplantation

Viruses, 2021
Gamma delta (γδ) T cells form an unconventional subset of T lymphocytes that express a T cell receptor (TCR) consisting of γ and δ chains. Unlike conventional αβ T cells, γδ T cells share the immune signature of both the innate and the adaptive immunity.
Ahmed Gaballa, Faisal Alagrafi, Michael Uhlin, Arwen Stikvoort   +3 more
doaj   +1 more source

Gamma-delta T cells modulate the microbiota and fecal micro-RNAs to maintain mucosal tolerance

Microbiome, 2023
Background Gamma-delta (γδ) T cells are a major cell population in the intestinal mucosa and are key mediators of mucosal tolerance and microbiota composition.
Rafael M. Rezende, Laura M. Cox, Thais G. Moreira, Shirong Liu, Selma Boulenouar, Fyonn Dhang, Danielle S. LeServe, Brenda N. Nakagaki, Juliana R. Lopes, Bruna K. Tatematsu, Luisa Lemos, Julia Mayrink, Eduardo L. C. Lobo, Lydia Guo, Marilia G. Oliveira, Chantal Kuhn, Howard L. Weiner   +16 more
doaj   +1 more source

γδ T cells in Skin Inflammation

, 2022
Gamma delta (γδ) T cells are a subset of T lymphocytes that express T cell receptor γ and δ chains and display structural and functional heterogeneity.
Kaplan, Mark H., Zhang, Wenwu, Pajulas, Abigail   +2 more
core   +1 more source

Gamma delta T-lymphocytes in hepatitis C and chronic liver disease

Frontiers in Immunology, 2014
Discovered thirty years ago, gamma delta (γδ) T-lymphocytes remain an intriguing and enigmatic T-cell subset. Although in humans they comprise a small fraction of the total circulating T-lymphocyte pool, they represent an important T-cell subset in ...
neil erajoriya, neil erajoriya, Joannah Ruth Fergusson, Jo eLeithead, Paul eKlenerman   +4 more
doaj   +1 more source

The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]

, 2012
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Harnett, M.M., Pineda, Miguel, McGrath, Mairi, Al-Riyami, Lamyaa, Pineda, M.A., Harnett, W., Pauline C. Smith, Lamyaa Al-Riyami, Harnett, Margaret, Miguel A. Pineda, Smith, P.C., Smith, Pauline, J. Alastair Gracie, Harnett, William, McGrath, M.A., Rzepecka, J., Gracie, Alastair, Rzepecka, Justyna, Margaret M. Harnett, Al-Riyami, L., Gracie, J.A., Justyna Rzepecka, Mairi A. McGrath, William Harnett   +23 more
core   +1 more source

Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host. [PDF]

Rev Med Virol
ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
Cimini E, Tartaglia E, Cristofanelli F, Gili S, Maggi F.   +4 more
europepmc   +2 more sources