Results 241 to 250 of about 2,836,933 (367)

Pannexins, a family of gap junction proteins expressed in brain

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2003
R. Bruzzone   +4 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca 2+ signals across the inner ear

open access: green, 2008
Fabio Anselmi   +11 more
openalex   +2 more sources

Gap junction protein connexin-43 interacts directly with microtubules [PDF]

open access: bronze, 2001
Ben N. G. Giepmans   +6 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

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