Results 51 to 60 of about 217,542 (316)

Large sample-to-sample fluctuations of the nonequilibrium critical current through mesoscopic Josephson junctions [PDF]

open access: yesPhys. Rev. B 63, 054512 (2001), 2000
We present a theory for the nonequilibrium current in a mesoscopic Josephson junction which is coupled to a normal electron reservoir, and apply it to a chaotic junction. Large sample-to-sample fluctuations of the critical current $I_{\rm c}$ are found, with ${rms} I_{\rm c} \simeq \sqrt{N}e\Delta/\hbar$, when the voltage difference eV between the ...
arxiv   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Platelet-derived growth factor PDGF-AA upregulates connexin 43 expression and promotes gap junction formations in osteoblast cells through p-Akt signaling

open access: yesBiochemistry and Biophysics Reports, 2023
Gap junctions, which are mainly composed of connexin units, play an indispensable role in cell morphogenesis, proliferation, migration, adhesion and differentiation of osteoblast lineage cells, and thus mediate bone development, homeostasis and disease ...
Tao Zuo   +6 more
doaj  

Modeling the role of gap junctions between excitatory neurons in the developing visual cortex.

open access: yesPLoS Computational Biology, 2021
Recent experiments in the developing mammalian visual cortex have revealed that gap junctions couple excitatory cells and potentially influence the formation of chemical synapses.
Jennifer Crodelle, David W McLaughlin
doaj   +1 more source

Current-Voltage Characteristics of Graphane p-n Junctions [PDF]

open access: yesIEEE Transactions on Electron Devices, vol. 57, no. 1, pp. 209-214 (2010), 2009
In contrast to graphene which is a gapless semiconductor, graphane, the hydrogenated graphene, is a semiconductor with an energy gap. Together with the two-dimensional geometry, unique transport features of graphene, and possibility of doping graphane, p and n regions can be defined so that 2D p-n junctions become feasible with small reverse currents ...
arxiv   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Gap state charge induced spin-dependent negative differential resistance in tunnel junctions [PDF]

open access: yes, 2016
We propose and demonstrate through first-principles calculation a new spin-dependent negative differential resistance (NDR) mechanism in magnetic tunnel junctions (MTJ) with cubic cation disordered crystals (CCDC) AlO$_x$ or Mg$_{1-x}$Al$_x$O as barrier materials. The CCDC is a class of insulators whose band gap can be changed by cation doping. The gap
arxiv   +1 more source

All-MgB2 Josephson tunnel junctions [PDF]

open access: yesPublished in Appl. Phys. Lett., 86 (2005) 172502, 2004
Sandwich-type all-MgB2 Josephson tunnel junctions (MgB2/AlOx/MgB2) have been fabricated for the first time with as-grown MgB2 films formed by molecular beam epitaxy. The junctions exhibit substantial superconducting current (IcRN product ~ 0.8 mV at 4.2K), a well-defined superconducting gap (delta = ~2.3 mV), and clear Fraunhofer patterns.
arxiv   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Gap junction channel gating

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2004
Over the last two decades, the view of gap junction (GJ) channel gating has changed from one with GJs having a single transjunctional voltage-sensitive (V(j)-sensitive) gating mechanism to one with each hemichannel of a formed GJ channel, as well as unapposed hemichannels, containing two, molecularly distinct gating mechanisms.
Feliksas F. Bukauskas, Vytas K. Verselis
openaire   +3 more sources

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