Results 61 to 70 of about 217,542 (316)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Molecular Vision, 2019 Purpose: The ocular trabecular meshwork (TM) responsible for aqueous humor (AH) drainage is crucial for regulating intraocular pressure (IOP) of the eye.
Hongxia +7 more
doaj
FEBS Open Bio, 2019 Connexins (Cx) are proteins that form cell‐to‐cell gap junction channels. A mutation at position 188 in the second extracellular loop (E2) domain of hCx46 has been linked to an autosomal dominant zonular pulverulent cataract.
Patrik Schadzek +3 more
doaj +1 more source
Disease Models & Mechanisms, 2014 Connexin40 (Cx40)-containing gap-junction channels are expressed in the atrial myocardium and provide a low-resistance passage for rapid impulse propagation.
Yiguo Sun +7 more
doaj +1 more source
Connexins evolved after early chordates lost innexin diversity
eLife, 2022 Gap junction channels are formed by two unrelated protein families. Non-chordates use the primordial innexins, while chordates use connexins that superseded the gap junction function of innexins.
Georg Welzel, Stefan Schuster
doaj +1 more source
Effect of inorganic cation mixing on hybrid halide perovskites using density functional theory for application in single and multi junction photovoltaics [PDF]
arXiv, 2021 This work is aimed to study mixed-cation (hybrid methyl ammonium plus inorganic cations) halide perovskites using first principles Density Functional Theory (DFT) formalism in order to find their potential applications in perovskite based photovoltaics. This is an addition to the two previous studies performed by the author on high-throughput screening
arxiv
Subharmonic gap structure in short ballistic graphene junctions [PDF]
Phys. Rev. B 74, 180501 (2006)., 2006 We present a theoretical analysis of the current-voltage characteristics of a ballistic superconductor-normal-superconductor (SNS) junction, in which a strip of graphene is coupled to two superconducting electrodes. We focus in the short-junction regime, where the length of the strip is much smaller than superconducting coherence length.
arxiv +1 more source
Minding the Gaps—and the Junctions, Too [PDF]
Circulation, 2012 Platelets may be small, but their behavior in vivo is governed by molecular mechanisms every bit as complex as those in larger cells. New molecules that provide unexpected insights turn up with surprising regularity. One recent example is the connexin family member Cx37 or GJA4.
Timothy J. Stalker, Lawrence F. Brass
openaire +3 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Thermal signature of Majorana fermions in Josephson junction [PDF]
Phys. Rev. B 103, 144502 (2021), 2019 Existence of distinctive correlation between the thermal conductance and the Josephson current across a 1-D topological Josephson junction (T-JJ) is established and an expression connecting the two is derived in the short junction limit. It is shown that the three terminal T-JJ provides us with an ideal set-up for exploiting the distinctive ...
arxiv +1 more source