Results 121 to 130 of about 149 (147)
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Gap Junctional Communication

Annual Review of Physiology, 1981
The formation of low resistance pathways is one of the most common forms of cellular interaction. Since its discovery between neurons (40) this form of cell-to-cell communication has been documented widely in both excitable and nonexcitable cells.
E L Hertzberg, T S Lawrence, N B Gilula
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Gap Junctions and Ageing

2023
Gap junctions, comprising connexin proteins, create conduits directly coupling the cytoplasms of adjacent cells. Expressed in essentially all tissues, dynamic gap junction structures enable the exchange of small molecules including ions and second messengers, and are central to maintenance of homeostasis and synchronized excitability. With such diverse
Michael J, Zeitz, James W, Smyth
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Chemistry of Gap Junctions

Annual Review of Physiology, 1985
Gap junctions [also called nexus (15) or maculae communicantes (102)] repre­ sent transcellular channels that permit the exchange of small molecules and ions between neighboring cells (28, 33, 74, 75, 82, 86, 89, 103). They differ from other membrane channels in a number of respects: they provide a pathway between cells rather than across one cell ...
Revel, J.-P.   +2 more
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Biophysics of gap junctions

Seminars in Cell Biology, 1992
Gap junction channels, now known to be formed of connexins, connect the interiors of apposed cells. These channels can be opened and closed by various physiological stimuli and experimental treatments. They are permeable to ions and neutral molecules up to a size of about 1 kDa or 1.5 nm diameter, including second messengers and metabolites.
M.V.L. Bennett, V.K. Verselis
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Tight Junctions and Gap Junctions [PDF]

open access: possible, 2010
Tight junctions have several major functions. They seal the intercellular space in epithelial and endothelial cell layers and prevent free paracellular passage of substances. They determine the polarity of epithelial cells by creating a boundary between the apical domain of the plasma membrane and the basolateral domain and prevent diffusion of lipids ...
Jürgen Roth, Margit Pavelka
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The electrophysiology of gap junctions and gap junction channels and their mathematical modelling

Biology of the Cell, 2002
Summry— In most tissues of vertebrates, gap junctions control the exchange of ions and small molecules between adjacent cells, thus co‐ordinating the cellular activities. The application of the dual voltage‐clamp method to cell pair preparations enables one to elucidate the electrical properties of gap junctions and gap junction channels.
Robert Weingart, Rolf Vogel
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The gap junction

Journal of Cell Science, 1988
ABSTRACT Gap junctions are intercellular structures that link cells and allow them to exchange ions and small metabolites without recourse to the extracellular space (for reviews and early references, see Goodenough, 1979; Loewen-stein, 1981).
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Quantification of gap junction selectivity [PDF]

open access: possibleAmerican Journal of Physiology-Cell Physiology, 2005
Gap junctions, which are essential for functional coordination and homeostasis within tissues, permit the direct intercellular exchange of small molecules. The abundance and diversity of this exchange depends on the number and selectivity of the comprising channels and on the transjunctional gradient for and chemical character of the permeant ...
Janis M. Burt, Jose F. Ek-Vitorin
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Invertebrate gap junctions

Journal of Cell Science, 1977
ABSTRACT Both glycerol and glutaraldehyde, the two most commonly used chemical aids in freeze-fracture studies, have been shown individually to affect the structure of certain membranes as observed in freeze-fracture replicas. The present investigation studied the effect of glycerol on the gap junctions found in a number of tissues from ...
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Increasing Gap Junctional Coupling: A Tool for Dissecting the Role of Gap Junctions

Journal of Membrane Biology, 2007
Much of our current knowledge about the physiological and pathophysiological role of gap junctions is based on experiments where coupling has been reduced by either chemical agents or genetic modification. This has brought evidence that gap junctions are important in many physiological processes. In a number of cases, gap junctions have been implicated
Axelsen, Lene Nygaard   +7 more
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