Results 131 to 140 of about 149 (147)
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Gap junctions–guards of excitability
Biochemical Society Transactions, 2015Cardiomyocytes are connected by mechanical and electrical junctions located at the intercalated discs (IDs). Although these structures have long been known, it is becoming increasingly clear that their components interact. This review describes the involvement of the ID in electrical disturbances of the heart and focuses on the role of the gap ...
Stroemlund, Line Waring +4 more
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1993
One of the main avenues by which cells communicate with each other is through transmembranous channels which span the extracellular space, thereby allowing the direct transfer of small molecules and ions. The size range of admitted molecules allows the diffusion of current-carrying ions such as K+, Na+, Cl-, and second messenger molecules such as cAMP,
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One of the main avenues by which cells communicate with each other is through transmembranous channels which span the extracellular space, thereby allowing the direct transfer of small molecules and ions. The size range of admitted molecules allows the diffusion of current-carrying ions such as K+, Na+, Cl-, and second messenger molecules such as cAMP,
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Gap junction proteins form specialized intercellular communication channels, including electrical synapses, that regulate cellular metabolism and signaling. We present a molecular inventory of the gap junction proteins-innexins (INX-like) in ctenophores, focusing on two reference species, Pleurobrachia bachei and Mnemiopsis leidyi.
Andrea B, Kohn, Leonid L, Moroz
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Andrea B, Kohn, Leonid L, Moroz
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Gap junction diseases of the skin
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 2004AbstractGap junctions are intercellular channels that allow the passage of water, ions, and small molecules. They are involved in quick, short‐range messaging between cells and are found in skin, nervous tissue, heart, and muscle. An increasing number of hereditary skin disorders appear to be caused by mutations in one of the genes coding for the ...
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Trends in Neurosciences, 1981
Abstract The hypothesis that gap junctions provide a pathway mediating the cellular interactions of embryonic development gained in attractiveness as gap junctions, electrotonic coupling and dye coupling were found in successively more embryos. Recent examples of the formation and disappearance of junctions show that this coupling can exhibit striking
David C. Spray +2 more
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Abstract The hypothesis that gap junctions provide a pathway mediating the cellular interactions of embryonic development gained in attractiveness as gap junctions, electrotonic coupling and dye coupling were found in successively more embryos. Recent examples of the formation and disappearance of junctions show that this coupling can exhibit striking
David C. Spray +2 more
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2016
Electrotonic coupling between cells is accomplished through the formation of gap junctions (GJs) between cells. Composed of connexin proteins, GJs are found on multiple cell types and connexin distribution is cell type-specific. All GJs play a role in cellular communication, but astrocytic GJs are thought to play a role in K+ and glutamate ...
Jacqueline A. Hubbard, Devin K. Binder
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Electrotonic coupling between cells is accomplished through the formation of gap junctions (GJs) between cells. Composed of connexin proteins, GJs are found on multiple cell types and connexin distribution is cell type-specific. All GJs play a role in cellular communication, but astrocytic GJs are thought to play a role in K+ and glutamate ...
Jacqueline A. Hubbard, Devin K. Binder
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Science Signaling, 2011
Neuronal gap junction channels containing connexin 36 proteins participate in consolidation of fear memories.
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Neuronal gap junction channels containing connexin 36 proteins participate in consolidation of fear memories.
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The Role of Gap Junctions in Development
Annual Review of Physiology, 1985The gap junction, a membrane specialization found in most growing and mature metazoan tissues, is the site of dynamic cell-to-cell channels permeable to inorganic ions and small organic metabolites (up to about Mr = 2000), These channels allow the cytoplasmic interiors of adjacent cells to be directly cou pled, in a functional sense, because in ...
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2000
Publisher Summary This chapter discusses the development in gap junctions. A role for gap junctions in development is proposed as the early studies show the presence of low resistance junctions in nonexcitable cells and tissues. These studies demonstrated that cells of various adult tissues and those of the early embryo generally exhibited low ...
Norton B. Gilula, Cecilia W. Lo
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Publisher Summary This chapter discusses the development in gap junctions. A role for gap junctions in development is proposed as the early studies show the presence of low resistance junctions in nonexcitable cells and tissues. These studies demonstrated that cells of various adult tissues and those of the early embryo generally exhibited low ...
Norton B. Gilula, Cecilia W. Lo
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