Results 151 to 160 of about 73,986 (253)

Influence of gap junctions upon Ca²⁺ propagation from stimulated keratinocytes to DRG neurons. [PDF]

Biophys Physicobiol, 2022
Seto C, Toyoda K, Inada K, Oka K, Ito E.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Multiple carbamylation events are required for differential modulation of Cx26 hemichannels and gap junctions by CO₂. [PDF]

J Physiol
Nijjar S, Brotherton D, Butler J, Dospinescu VM, Gannon HG, Linthwaite V, Cann M, Cameron A, Dale N.   +8 more
europepmc   +1 more source

Confocal Laser and Electron Microscopic Investigation of Gap Junctions in Anaplastic Astrocytomas. [PDF]

Adv Exp Med Biol, 2022
Logvinov AK, Kirichenko EY, Sehweil SMM, Bragin DE, Logvinova IK, Ermakov AM.   +5 more
europepmc   +1 more source

Gap Junction [PDF]

, 2020
openaire   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Hypoxia-preconditioning human bone marrow-derived mesenchymal stem cells induce high-quality mitochondrial transfer through gap junctions to alleviate ischemia-reperfusion injury in liver graft. [PDF]

Cell Commun Signal
Luo X, Zeng W, Xiong E, Wang Z, Huang J, Luo M, He Z, Liu J, Yuan D.   +8 more
europepmc   +1 more source

GAP junctions: multifaceted regulators of neuronal differentiation. [PDF]

Tissue Barriers, 2022
Talukdar S, Emdad L, Das SK, Fisher PB.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Endothelial-adipocyte Cx43 Mediated Gap Junctions Can Regulate Adiposity. [PDF]

Function (Oxf)
Luse MA, Dunaway LS, Nyshadham S, Carvalho A, Sedovy MW, Ruddiman CA, Tessema R, Hirschi K, Johnstone SR, Isakson BE.   +9 more
europepmc   +1 more source