Results 241 to 250 of about 24,180 (354)

Adsorption of antigen to polymeric nanoparticles enhances cytotoxic T‐cell responses and anti‐tumor immunity by targeting conventional type 1 dendritic cells

Immunology &Cell Biology, Volume 103, Issue 9, Page 825-843, October 2025.
Therapeutic cancer vaccines require CD8+ T‐cell activation for efficacy. This response can be enhanced by rationally designing polymeric nanoparticle adjuvants. The importance of antigen location for the adjuvanticity of polymeric nanoparticles has not been fully resolved.
Jorge Huete‐Carrasco, Jingjing Zhu, Benoit J Van den Eynde, Christian Thomas Mayer, Tim Sparwasser, Ross W Ward, Ed C Lavelle   +6 more
wiley   +1 more source

Spermidine mitigates lipopolysaccharide-induced acute lung injury by enhancing autophagic flux. [PDF]

Biomed Rep
Zhang X, Lu H, Xu X.
europepmc   +1 more source

N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting [PDF]

, 2015

core   +1 more source

Copper Homeostasis, Emerging Central Players in Cancer Immunotherapy

Journal of Cellular and Molecular Medicine, Volume 29, Issue 19, October 2025.
ABSTRACT Copper ions serve as multifunctional signalling molecules that are integral to various cellular processes in vivo, including cell proliferation, apoptosis and migration. The storage, transport and homeostatic regulation of intracellular copper are closely linked to mitochondrial function.
Chengxin Chen, Mengle Peng, Shuhong Liang, Chunwei Li, Lili Zhu, Yaqi Yang, Lifeng Li, Wenhua Xue   +7 more
wiley   +1 more source

Expression of GSDMs in glioma and its influence on prognosis. [PDF]

Medicine (Baltimore)
Liu K, Chen S, Hu T, Zhang X, Huang Q.
europepmc   +1 more source

Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies

, 2022
Bowen Zhou, Christopher B. Ryder, George Dubyak, Derek W. Abbott   +3 more
openalex   +1 more source

TGFBI Inhibits the Pyroptosis of Macrophages to Ameliorate Septic Shock

Journal of Cellular and Molecular Medicine, Volume 29, Issue 19, October 2025.
ABSTRACT Septic shock is one of the leading causes of morbidity and mortality in hospital patients. The present study aimed to investigate the potential of transforming growth factor β induced (TGFBI) in macrophage functions and progression of septic shock.
Suzhao Zou, Lan Li, Bo Lv
wiley   +1 more source

A novel role of liquid plasma (LP) induced RONS triggers the endoplasmic reticulum stress response and is associated with GSDME-mediated pyroptosis in anaplastic thyroid cancer. [PDF]

Cell Commun Signal
Ji EJ, Yeou SH, Kang SU, Kim CH.
europepmc   +1 more source

SUMOylation of ZEB1 Modulates PANoptosis in Burn‐Induced Early Acute Kidney Injury

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT Burn‐induced acute kidney injury (AKI) involves inflammatory programmed cell death pathways, including PANoptosis. This study investigated how SUMOylation of the transcription factor ZEB1 regulates PANoptosis in early burn‐induced AKI. Human AKI datasets were analyzed for ZEB1 expression and correlation with PANoptosis/SUMOylation genes. A rat
Juncheng Zhang, Zhengjie Huang, Qin Lin, Hongbin Zhong, Weiping Hu, Fengling Zhang, Jiyi Huang   +6 more
wiley   +1 more source

CDC5L binds to ELAVL1 to inhibit pyroptosis in hepatocellular carcinoma through the Caspase 3/GSDME signaling pathway. [PDF]

Int J Mol Med
Liang S, Zhu Z, Tang Y, Zhou S, Xiao M, Gong X, Ye K.   +6 more
europepmc   +1 more source