Results 171 to 180 of about 15,764 (222)

ATP8B1 regulates PIP2 localization and cleavage of pyroptotic executioner Gasdermin D. [PDF]

Proc Natl Acad Sci U S A
Bhandari N, Prince A, Khan MR, Traughber CA, Neupane K, Lorkowski SW, Brubaker G, Ertugral EG, Kothapalli CR, Dubyak GR, Smith JD, Gulshan K.   +11 more
europepmc   +1 more source

Gasdermin D is activated but does not drive neurodegeneration in SOD1^G93A model of ALS: Implications for targeting pyroptosis. [PDF]

Neurobiol Dis
Gunner G, Basu H, Lu Y, Bergstresser M, Sun L, Neel D, Choi SY, Chiu IM.   +7 more
europepmc   +1 more source

ALIX mediates reversible gasdermin-D pore formation via the endosomal pathway to limit pyroptosis by active membrane repair. [PDF]

Cell Death Dis
Otchere S, Shrestha P, Parmar HN, Perry JF, Hofmeister BL, Steyn M, Kaushik RS, Hoppe AD, Thiex NW, Hanson RL, Lopez-Mosqueda J, Imre G.   +11 more
europepmc   +1 more source

Extracellular Lipopolysaccharide Triggers the Release of Unconjugated Interferon-Stimulated Gene 15 (ISG15) Protein from Macrophages via Type-I Interferon/Caspase-4/Gasdermin-D Pathway. [PDF]

Pathogens
Pandit S, Miller LG, Mohanty I, Bose S.
europepmc   +1 more source

The SARS-CoV-2 3CL protease inhibits pyroptosis through the cleavage of gasdermin D. [PDF]

Virol Sin
Zhang Y, Ji X, Huang D, Lu G, Chen X.
europepmc   +1 more source

Ocifisertib alleviates the gasdermin D-independent pyroptosis of nucleus pulposus cells by targeting GSDME. [PDF]

Sci Rep
Lin Y, Chen Q, Liu S, Liu B.
europepmc   +1 more source

Gasdermin D unlocks metabolic pathways to enhance tissue regeneration. [PDF]

Cell Mol Immunol
Shubhra QTH.
europepmc   +1 more source

NEK7 phosphorylation amplifies NLRP3 inflammasome activation downstream of potassium efflux and gasdermin D. [PDF]

Sci Immunol
Xu J, Zhang L, Duan Y, Sun F, Odeh N, He Y, Núñez G.   +6 more
europepmc   +1 more source

Gasdermin D-Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis. [PDF]

Adv Sci (Weinh)
Liu C, Liang N, Wu C, Qiu Z, Huang Q, Wei X, Zhang S, Lei S, Yang T, Wang G, Wang Q.   +10 more
europepmc   +1 more source