Results 51 to 60 of about 160,008 (264)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Radioimmunoassay of gastrointestinal hormones

Gastroenterology, 1978
In 1833, William Beaumont published his Experiments and Observations on the Gastric Juice and the Physiology of Digestion. He had tracked, cajoled, forced, and studied his reluctant patient, Alexis St. Martin, whose gastric fistula was Beaumont's window into the wonders of digestion, until he had formed the modern study of digestive processes and ...
openaire   +2 more sources

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Potential role of glucagon like peptide 1 in taste receptors

Frontiers in Endocrinology
The perception of taste is a complex physiological process that extends far beyond the simple detection of flavor molecules, serving as a critical interface between nutrient sensing, metabolic regulation, and feeding behavior.
Jose Luis Eduardo Doval-Caballero, Aldo Ferreira-Hermosillo, Genesis Dinora Eugenio-Ponce, Manuel Ramon García-Sáenz, Raúl Ibarra-Salce, Andrea Patricia Tenorio-Rojo, Eduardo Salif Luna-Avila, Paulo César Gete-Palacios, Fernando Pérez-Hernández, Eduardo Rojas-Milán, Luis Angel López-Cruz, César Alejandro Méndez-Hernández   +11 more
doaj   +1 more source

Laxative Effects of Phlorotannins Derived from Ecklonia cava on Loperamide-Induced Constipation in SD Rats

Molecules, 2021
This study investigated the laxative effects of phlorotannins (Pt) derived from Ecklonia cava (E. cave) on chronic constipation by evaluating alterations in stool parameters, gastrointestinal motility, histopathological structure, mucin secretion ...
Ji-Eun Kim, Yun-Ju Choi, Su-Jin Lee, Jeong-Eun Gong, You-Jung Jin, So-Hae Park, Hee-Seob Lee, Young-Whan Choi, Jin-Tae Hong, Dae-Youn Hwang   +9 more
doaj   +1 more source

Pediatric Obesity: Influence on Drug Dosing and Therapeutics [PDF]

, 2018
Obesity is an ongoing global health concern and has only recently been recognized as a chronic disease of energy homeostasis and fuel partitioning. Obesity afflicts 17% of US children and adolescents.
Ameer, Barbara, PharmD, MBA, BCPS, FCP, Weintraub, Michael, MD   +1 more
core   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

A Role for the Intestinal Microbiota and Virome in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)? [PDF]

, 2016
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous disorder of significant societal impact that is proposed to involve both host and environmentally derived aetiologies that may be autoimmune in nature. Immune-related symptoms
Acheson, Bassi, Burbelo, Caligiuri, Carlo-Stella, Collins, Enbom, Fattah, Fremont, Gill, Jason, Klein, Klimas, Kumar, Lerner, Lerner, Maes, Meeus, Nishikai, Sharpe, Sheedy, Tannock, Vollmer-Conna   +22 more
core   +2 more sources