Results 1 to 10 of about 7,571 (179)

Brachyury in the gastrula of basal vertebrates

Mechanisms of Development, 2020
The Brachyury gene encodes a transcription factor that is conserved across all animals. In non-chordate metazoans, brachyury is primarily expressed in ectoderm regions that are added to the endodermal gut during development, and often form a ring around the site of endoderm internalization in the gastrula, the blastopore.
Ashley E E Bruce, Rudolf Winklbauer
exaly   +3 more sources

CLDN10-driven lineage decision in an amnion and primordial germ cell progenitor at the amnion-epiblast boundary in primates [PDF]

Genome Biology
Background A growing body of evidence from primate embryos as well as in vitro systems supports the notion that amnion and primordial germ cell (PGC) lineage progressing cells share a common precursor.
Nikola Sekulovski, Amber E. Carleton, Anusha Rengarajan, Chien-Wei Lin, Maliha Kabir, Lauren N. Juga, Allison E. Whorton, Lauren E. Elberfeld, Jenna C. Wettstein, Jenna K. Schmidt, Thaddeus G. Golos, Kenichiro Taniguchi   +11 more
doaj   +2 more sources

Primordial germ cell specification and early developmental cell states in Pacific oyster [PDF]

BMC Genomics
Background Primordial germ cells (PGCs) are the precursor cells of gametes and pivotal in understanding reproductive and developmental biology. Importantly, having a thorough understanding of PGC specification is leading to critical advances in sterility
Mackenzie R. Gavery, Lauren E. Vandepas, Lauren M. Saunders, Brent Vadopalas, J. Adam Luckenbach, Cole Trapnell, Steven Roberts   +6 more
doaj   +2 more sources

Transcriptomic profiling of three embryonic development stages in Rare Minnow (Gobiocypris rarus) [PDF]

Scientific Data
Rare minnow (Gobiocypris rarus), a model organism with a transparent chorion and sensitivity to chemicals, is widely used in toxicology and developmental biology.
Xinhua Zou, Chunling Wang, Yongfeng He, Jianwei Wang   +3 more
doaj   +2 more sources

Illyaa Ilyich Mechnikov: life and work [PDF]

Annals of Mechnikov's Institute, 2020
On May 15, 2020, we celebrated the 175th anniversary of the Ilya Metchnikoff, the author of the hypothesis about parenchymella, the father of cellular immunology and inflammation theory, founder of gerontology, aging and longevity science.
Minukhin V. V., Kolotova T. Yu., Skliar N. I., Voronkina I.A., Davidenko M.B., Kazmirchuk V.V.   +5 more
doaj   +1 more source

Tissue Rotation of the Xenopus Anterior–Posterior Neural Axis Reveals Profound but Transient Plasticity at the Mid-Gastrula Stage

Journal of Developmental Biology, 2022
The establishment of anterior–posterior (AP) regional identity is an essential step in the appropriate development of the vertebrate central nervous system. An important aspect of AP neural axis formation is the inherent plasticity that allows developing
Lyuba Bolkhovitinov, Bryan T. Weselman, Gladys A. Shaw, Chen Dong, Janhavi Giribhattanavar, Margaret S. Saha   +5 more
doaj   +1 more source

Transcriptomic Analysis and Time to Hatch Visual Prediction of Embryo Development in the Ornate Spiny Lobster (Panulirus ornatus)

Frontiers in Marine Science, 2022
The ability to conduct closed life-cycle culture of tropical spiny lobsters, Panulirus ornatus, at the Institute for Marine and Antarctic Studies (IMAS) provides a unique opportunity to investigate specific developmental stages during embryogenesis.
Courtney L. Lewis, Courtney L. Lewis, Quinn P. Fitzgibbon, Gregory G. Smith, Abigail Elizur, Tomer Ventura, Tomer Ventura   +6 more
doaj   +1 more source

CRISPR/Cas9 establishment-mediated targeted mutagenesis in Macrobrachium nipponense

Frontiers in Physiology, 2023
Introduction: CRISPR/Cas9 is a gene-editing technology which could specifically cleave dsDNA and induce target gene mutation. CRISPR/Cas9 has been widely used in gene functional studies in many fields, such as medicine, biology, and agriculture due to ...
Hui Qiao, Hui Qiao, Sufei Jiang, Sufei Jiang, Hongtuo Fu, Hongtuo Fu, Yiwei Xiong, Wenyi Zhang, Lei Xu, Dan Cheng, Jisheng Wang   +10 more
doaj   +1 more source

Pou5f1/Oct4 promotes cell survival via direct activation of mych expression during zebrafish gastrulation. [PDF]

PLoS ONE, 2014
Myc proteins control cell proliferation, cell cycle progression, and apoptosis, and play important roles in cancer as well in establishment of pluripotency. Here we investigated the control of myc gene expression by the Pou5f1/Oct4 pluripotency factor in
Kay Kotkamp, Esther Kur, Björn Wendik, Bożena K Polok, Shifra Ben-Dor, Daria Onichtchouk, Wolfgang Driever   +6 more
doaj   +1 more source

Early development of the central and peripheral nervous systems is coordinated by Wnt and BMP signals. [PDF]

PLoS ONE, 2008
The formation of functional neural circuits that process sensory information requires coordinated development of the central and peripheral nervous systems derived from neural plate and neural plate border cells, respectively.
Cédric Patthey, Lena Gunhaga, Thomas Edlund   +2 more
doaj   +1 more source