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Notch coordinates self-organization of germ layers and axial polarity in cnidarian gastruloids
Narayanaswamy S +4 more
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Gastrula organiser and embryonic patterning in the mouse
Seminars in Cell and Developmental Biology, 2004Embryonic patterning of the mouse during gastrulation and early organogenesis engenders the specification of anterior versus posterior structures and body laterality by the interaction of signalling and modulating activities. A group of cells in the mouse gastrula, characterised by the expression of a repertoire of "organiser" genes, acts as a source ...
Lorraine, Robb, Patrick P L, Tam
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Cell migration in the Xenopus gastrula
WIREs Developmental Biology, 2018Xenopus gastrulation movements are in large part based on the rearrangement of cells by differential cell‐on‐cell migration within multilayered tissues. Different patterns of migration‐based cell intercalation drive endoderm and mesoderm internalization and their positioning along their prospective body axes.
Yunyun, Huang, Rudolf, Winklbauer
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Glycoprotein secretion by isolated rana pipiens gastrula chordamesoderm
Cell Differentiation, 1980Abstract It has been confirmed that involuted chordamesoderm, when placed in the blastocoele cavity of early Rana pipiens gastrulae, induces the formation of anterior neural structures. Isolates of chordamesoderm grown in vitro release macromolecules which incorporate [ 3 H]leucine, [ 14 C]glucosamine and [ 14 C]acetate but not [ 3 H]uridine or Na ...
D D, Kaska, E L, Triplett
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Directional mesoderm cell migration in the Xenopus gastrula
Developmental Biology, 1991The movement of the dorsal mesoderm across the blastocoel roof of the Xenopus gastrula is examined. We show that different parts of the mesoderm which can be distinguished by their morphogenetic behavior in the embryo are all able to migrate independently on the inner surface of the blastocoel roof.
R, Winklbauer, M, Nagel
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Mesoderm migration in the Xenopus gastrula.
The International Journal of Developmental Biology, 1996During Xenopus gastrulation, the mesoderm involutes at the blastopore lip and moves on the inner surface of the BCR toward the animal pole of the embryo. Active cell migration is involved in this mesoderm translocation. In vitro, mesoderm cells migrate non-persistently and intermittently by extending and retracting multiple lamellipodia, which pull the
R, Winklbauer +3 more
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Glycosaminoglycan synthesis in the chick gastrula
Developmental Biology, 1976Explanted definitive primitive streak to four somite chick embryos were labeled with [H3]glucosamine or S35O4 and the glycosaminoglycans were isolated and characterized. On the basis of susceptibility to Streptomyces hyaluronidase, which specifically degrades hyaluronic acid, hyaluronic acid is the major glycosaminoglycan produced by these embryos (at ...
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Building the mouse gastrula: signals, asymmetry and lineages
Current Opinion in Genetics & Development, 2006The mouse embryo is built by assembling the progenitors of various tissue types into a body plan. Early postimplantation development involves the establishment of anatomical asymmetries and regionalized gene expression in the conceptus, the specification of tissue lineages, and the coordination of cell movement for correct positioning of the lineage ...
Patrick P L, Tam +2 more
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Cell–cell contact landscapes in Xenopus gastrula tissues
Proceedings of the National Academy of Sciences, 2021Significance Distinct cell contacts like adherens junctions or desmosomes are well studied. Understanding the seemingly amorphous structures of cell–cell adhesion in many tissues still poses a challenge. Here, we explore the landscape of adhesive contacts in Xenopus gastrula
Debanjan Barua +2 more
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Journal of Experimental Zoology, 1989
AbstractExperiments were performed to examine adhesion of Rana pipiens gastrula cells and arrested hybrid gastrula cells to fibronectin‐Sepharose beads (FN‐beads). Blastula cells from both normal and hybrid embryos show poor adhesion to FN‐beads. Beginning at the early gastrula stage, however, normal cells show a progressively increasing tendency to ...
K E, Johnson, M H, Silver
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AbstractExperiments were performed to examine adhesion of Rana pipiens gastrula cells and arrested hybrid gastrula cells to fibronectin‐Sepharose beads (FN‐beads). Blastula cells from both normal and hybrid embryos show poor adhesion to FN‐beads. Beginning at the early gastrula stage, however, normal cells show a progressively increasing tendency to ...
K E, Johnson, M H, Silver
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