Zebrafish as a Model for Fetal Alcohol Spectrum Disorders
Frontiers in Pharmacology, 2021 In this review, we will discuss zebrafish as a model for studying mechanisms of human fetal alcohol spectrum disorders (FASDs). We will overview the studies on FASDs so far and will discuss with specific focus on the mechanisms by which alcohol alters ...
Amena Alsakran +2 more
doaj +1 more source
Metabolites, 2022 Many previous studies have reported the various proteins specifically secreted as inducers in the dorsal or ventral regions in vertebrate gastrula. However, little is known about the effect on cell fate of small molecules below 1000 Da.
Yukako Suzuki +7 more
doaj +1 more source
Phosphorylation-dependent ubiquitination of paraxial protocadherin (PAPC) controls gastrulation cell movements. [PDF]
PLoS ONE, 2015 Paraxial protocadherin (PAPC) has been shown to be involved in gastrulation cell movements during early embryogenesis. It is first expressed in the dorsal marginal zone at the early gastrula stage and subsequently restricted to the paraxial mesoderm in ...
Masatake Kai +2 more
doaj +1 more source
Efecto de la salinidad en la embriogénesis del erizo de mar Arbacia stellata (Blainville, 1825)
La Técnica: Revista de las Agrociencias, 2021 El erizo de mar Arbacia stellata puede habitar en ecosistemas estuarinos, pero se desconoce la salinidad crítica en las etapas iniciales de vida para su cultivo.
Edgar Alexander Zapata Vìvenes +3 more
doaj +1 more source
Skeletogenic Expression of Integrin Alpha, Talin and Npnt Genes and Npnt Role in Sea Urchin Skeletogenesis. [PDF]
J Exp Zool B Mol Dev EvolThree integrin alpha genes and the cytoskeletal adaptor talin are enriched in sea urchin skeletogenic cells during early skeletogenesis. The extracellular matrix protein nephronectin (Npnt) is expressed in the skeletogenic cells throughout skeletogenesis and supports normal skeletal growth, highlighting a potential role for cell–matrix interactions in ...
Chen S +3 more
europepmc +2 more sources
Pre-gastrula expression of zebrafish extraembryonic genes [PDF]
BMC Developmental Biology, 2010 Abstract Background Many species form extraembryonic tissues during embryogenesis, such as the placenta of humans and other viviparous mammals. Extraembryonic tissues have various roles in protecting, nourishing and patterning embryos.
Hong, Sung-Kook +7 more
openaire +2 more sources
Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer
eLife, 2020 Deciphering the mechanisms of axis formation in amphioxus is a key step to understanding the evolution of chordate body plan. The current view is that Nodal signaling is the only factor promoting the dorsal axis specification in the amphioxus, whereas ...
Iryna Kozmikova, Zbynek Kozmik
doaj +1 more source
Differential responses to Wnt and PCP disruption predict expression and developmental function of conserved and novel genes in a cnidarian. [PDF]
PLoS Genetics, 2014 We have used Digital Gene Expression analysis to identify, without bilaterian bias, regulators of cnidarian embryonic patterning. Transcriptome comparison between un-manipulated Clytia early gastrula embryos and ones in which the key polarity regulator ...
Pascal Lapébie +7 more
doaj +1 more source
Foxd4l1.1 Negatively Regulates Chordin Transcription in Neuroectoderm of Xenopus Gastrula
Cells, 2021 Inhibition of the bone morphogenetic proteins (BMPs) is the primary step toward neuroectoderm formation in vertebrates. In this process, the Spemann organizer of the dorsal mesoderm plays a decisive role by secreting several extracellular BMP inhibitors ...
Vijay Kumar +5 more
doaj +1 more source
Sequencing and analysis of the gastrula transcriptome of the brittle star
EvoDevo, 2012 Background The gastrula stage represents the point in development at which the three primary germ layers diverge. At this point the gene regulatory networks that specify the germ layers are established and the genes that define the differentiated states ...
Vaughn Roy +4 more
doaj +1 more source