Results 71 to 80 of about 10,115 (192)
Developmental Dynamics, EarlyView.Abstract Homology in vertebrate body plans is traditionally ascribed to the high‐level conservation of regulatory components within the genetic programs governing them, particularly during the “phylotypic stage.” However, advancements in embryology and molecular phylogeny have unveiled the dynamic nature of gene repertoires responsible for early ...
Shigehiro Kuraku
wiley +1 more source
Spinal dysraphism illustrated; Embroyology revisited
Indian Journal of Radiology and Imaging, 2017 Spinal cord development occurs through three consecutive periods of gastrulation, primary nerulation and secondary neurulation. Aberration in these stages causes abnormalities of the spine and spinal cord, collectively referred as spinal dysraphism. They
Ullas V Acharya +4 more
doaj +1 more source
Genetic Deletion of miR-430 Disrupts Maternal-Zygotic Transition and Embryonic Body Plan
Frontiers in Genetics, 2020 MiR-430 is considered an important regulator during embryonic development, but genetic loss-of-function study is still lacking. Here we demonstrated that genetic deletion of the miR-430 cluster resulted in developmental defects in cell movement, germ ...
Yun Liu +9 more
doaj +1 more source
Developmental Dynamics, EarlyView.Abstract Background The avian node is the equivalent of the amphibian Spemann's organizer, as indicated by its ability to induce a secondary axis, cellular contribution, and gene expression, whereas the node of the mouse, which displays limited inductive capacities, was suggested to be a part of spatially distributed signaling.
Braah Harmoush +2 more
wiley +1 more source
eLife, 2020 During mammalian gastrulation, germ layers arise and are shaped into the body plan while extraembryonic layers sustain the embryo. Human embryonic stem cells, cultured with BMP4 on extracellular matrix micro-discs, reproducibly differentiate into ...
Kyaw Thu Minn +7 more
doaj +1 more source
Unde venisti PGRMC? Grand-Scale Biology from Early Eukaryotes and Eumetazoan Animal Origins
Frontiers in Bioscience-Landmark, 2022 The title usage of Unde venisti ‘from where have you come’ is from a now dead language (Latin) that foundationally influenced modern English (not the major influence, but an essential formative one).
Michael A. Cahill
doaj +1 more source
Scientific Reports, 2018 Marijuana is one of the most commonly used illicit recreational drugs and is widely used for medicinal purposes. The psychoactive ingredient in marijuana is ∆9-tetrahydrocannabinol (∆9-THC), whereas the major non-psychoactive ingredient is cannabidiol ...
K. T. Ahmed +3 more
semanticscholar +1 more source
Molecular anatomy of emerging Xenopus left–right organizer at successive developmental stages
Developmental Dynamics, EarlyView.Abstract Background Vertebrate left–right symmetry breaking is preceded by formation of left–right organizer. In Amphibian, this structure is formed by gastrocoel roof plate, which emerges from superficial suprablastoporal cells. GRP is subdivided into medial area, which generates leftward flow by rotating monocilia and lateral Nodal1 expressing areas,
Natalia Petri +3 more
wiley +1 more source
CTCF looping is established during gastrulation in medaka embryos
bioRxiv, 2018 Genome architecture plays a critical role in gene regulation, but how the structures seen in mature cells emerge during embryonic development remains poorly understood.
Ryohei Nakamura +14 more
semanticscholar +1 more source
Developmental Dynamics, EarlyView.Abstract Breaking radial symmetry for anterior–posterior axis formation is one of the key developmental steps of vertebrate gastrulation and is established through a succession of transient domains defined by morphology or gene expression. Three such domains were interpreted recently in the rabbit to be part of a “three‐anchor‐point model” for axis ...
Ruben Plöger +2 more
wiley +1 more source