Results 91 to 100 of about 54,955 (220)
GATA-3 Expression in Trophoblastic Tissues [PDF]
American Journal of Surgical Pathology, 2015 Immunohistochemical expression of GATA-3 is seen predominantly in non-neoplastic bladder and breast epithelium and their respective carcinomas; however, data on expression in normal and lesional trophoblastic tissues are limited. Immunohistochemical staining for GATA-3 was assessed in a range of normal/lesional trophoblastic tissues and tumors in the ...
Natalie, Banet +12 more
openaire +2 more sources
Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells [PDF]
, 2016 Innate lymphoid cells (ILCs) patrol environmental interfaces to defend against infection and protect barrier integrity. Using a genetic tuning model, we demonstrate that the signal-dependent transcription factor (TF) STAT5 is critical for accumulation of
Villarino, Alejandro V^ +9 more
core +1 more source
Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality [PDF]
, 2016 Innate lymphoid cells (ILCs) play key roles in host defense, barrier integrity, and homeostasis and mirror adaptive CD4(+) T helper (Th) cell subtypes in both usage of effector molecules and transcription factors.
Brooks, Stephen R. +9 more
core +1 more source
Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury
Med Research, EarlyView.ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang +13 more
wiley +1 more source
Xiehe Yixue ZazhiObjectiveTo investigate the expression and clinical significance of GATA-3 and H3K27me3 in Tibetan patients with bladder urothelial carcinoma (BUC).MethodsBUC and normal bladder tissues were collected retrospectively from January 2016 to December 2021 in
NIMA Zhuoma +8 more
doaj +1 more source
Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells. [PDF]
PLoS ONE, 2012 BACKGROUND: Compound A (CpdA) is a dissociating non-steroidal glucocorticoid receptor (GR) ligand which has anti-inflammatory properties exerted by down-modulating proinflammatory gene expression.
Ana C Liberman +11 more
doaj +1 more source
Ashcroft v. Iqbal: The Question of a Heightened Standard of Pleading in Qualified Immunity Cases [PDF]
, 2009 Background We have previously shown that Lactobacillus reuteri supplementation from pregnancy week 36 and to the infant through the first year of life decreased the prevalence of IgE-associated eczema at 2 years.
Abrahamsson, Thomas +3 more
core +3 more sources
Medicinal Research Reviews, EarlyView.ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
HiJAKing innate lymphoid cells? [PDF]
, 2017 The family of innate lymphoid cells (ILCs) consists of a heterogeneous group of cytokine-producing cells that have features in common with adaptive T helper (Th) cells.
Gadina, Massimo +2 more
core +1 more source
People and Nature, EarlyView.Abstract Ecosystem services are rapidly degrading under anthropogenic pressure. Therefore, it is increasingly important to understand how ecosystem services flow, particularly at local scales, where people directly rely on nature for their livelihoods and well‐being. Many ecosystem services are underpinned by ecological (e.g.
Anna Stanworth +8 more
wiley +1 more source