Results 91 to 100 of about 18,813,060 (218)
Медицинская иммунология, 2014 . The review article summarizes current information about transcriptional factors Fохр3, GATA- 3, РАХ-5 and their cooperative interactions. Predomination of one of these factors leads to production of corresponding cytokines and appropriate changes in T ...
V. N. Mineev +4 more
doaj +1 more source
The GATA-3 gene is expressed during human kidney embryogenesis
Kidney International, 1995 GATA-3 is a transcription factor involved in the differentiation of T lymphocytes and additionally expressed in several chicken and mouse embryonic tissues. Using in situ hybridization, we found that the human GATA-3 gene is selectively expressed in the developing kidney. GATA-3 mRNA is first detected in the Wolffian duct from the time of its emergence
Labastie, Marie-Claude +3 more
openaire +2 more sources
PU.1 Regulates TCR Expression by Modulating GATA-3 Activity [PDF]
The Journal of Immunology, 2009 Abstract The Ets transcription factor PU.1 is a master regulator for the development of multiple lineages during hematopoiesis. The expression pattern of PU.1 is dynamically regulated during early T lineage development in the thymus. We previously revealed that PU.1 delineates heterogeneity of effector Th2 populations.
Hua-Chen, Chang +5 more
openaire +2 more sources
miRNA‑135a regulates Hut78 cell proliferation via the GATA‑3/TOX signaling pathway.
Molecular Medicine Reports, 2019 The present study investigated the role of microRNA‑135a (miR‑135a) in cutaneous T‑cell lymphoma (CTCL) proliferation. Compared with the normal T lymphocyte control cell line, the mRNA and protein levels of GATA binding protein 3 (GATA‑3) were markedly ...
Hong Wei +5 more
semanticscholar +1 more source
MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation. [PDF]
, 2017 MicroRNAs (miRNAs) exert powerful effects on immunity through coordinate regulation of multiple target genes in a wide variety of cells. Type 2 innate lymphoid cells (ILC2s) are tissue sentinel mediators of allergic inflammation.
Ansel, K Mark +7 more
core +2 more sources
The influence of artesunate on T-bet /GATA-3 equilibrium of peripheral blood in oral lichen planus
口腔疾病防治, 2016 Objective To explore influence of artesunate on T-bet /GATA-3 equilibrium of peripheral blood in oral lichen planus.Methods 18 OLP patients were selected,and peripheral blood mononuclear cells (PBMCs) were isolated by density gradient centrifugation. The
LIU Li-fang +3 more
doaj +1 more source
Effector/memory CD4 T cells making either Th1 or Th2 cytokines commonly co-express T-bet and GATA-3
PLoS ONE, 2017 Naïve CD4 T (NCD4T) cells post-activation undergo programming for inducible production of cytokines leading to generation of memory cells with various functions.
Arundhoti Das +6 more
semanticscholar +1 more source
Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality [PDF]
, 2016 Innate lymphoid cells (ILCs) play key roles in host defense, barrier integrity, and homeostasis and mirror adaptive CD4(+) T helper (Th) cell subtypes in both usage of effector molecules and transcription factors.
Brooks, Stephen R. +9 more
core +1 more source
HiJAKing innate lymphoid cells? [PDF]
, 2017 The family of innate lymphoid cells (ILCs) consists of a heterogeneous group of cytokine-producing cells that have features in common with adaptive T helper (Th) cells.
Gadina, Massimo +2 more
core +1 more source
Xiehe Yixue ZazhiObjectiveTo investigate the expression and clinical significance of GATA-3 and H3K27me3 in Tibetan patients with bladder urothelial carcinoma (BUC).MethodsBUC and normal bladder tissues were collected retrospectively from January 2016 to December 2021 in
NIMA Zhuoma +8 more
doaj +1 more source