Results 31 to 40 of about 54,955 (220)

A gene regulatory network armature for T lymphocyte specification [PDF]

, 2008
Choice of a T lymphoid fate by hematopoietic progenitor cells depends on sustained Notch–Delta signaling combined with tightly regulated activities of multiple transcription factors. To dissect the regulatory network connections that mediate this process,
Bolouri, Hamid, David-Fung, Elizabeth-Sharon, Georgescu, Constantin, Longabaugh, William J. R., Rothenberg, Ellen V., Scripture-Adams, Dierdre D., Yui, Mary A., Zarnegar, Mark A.   +7 more
core   +2 more sources

Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3 [PDF]

, 2007
GATA-3 is essential for T cell development from the earliest stages. However, abundant GATA-3 can drive T lineage precursors to a non–T cell fate, depending on Notch signaling and developmental stage.
B Heavey, C Nishiyama, C-N Ting, CB Franco, CC Chen, CV Laiosa, CV Laiosa, D Allman, D Chen, E Crivellato, E Ishiko, Ellen V Rothenberg, ES David-Fung, EV Rothenberg, FM Burnet, FY Tsai, G Balciunaite, G Hernández-Hoyos, H Igarashi, H Iwasaki, H Iwasaki, H-R Rodewald, HQ Shen, I Visan, J Zhu, J Zhu, JA Grass, JC Walsh, JC Zúñiga-Pflücker, K Shortman, K Tomita, M Babina, M Mohtashami, M Murphy, M Zhou, Mary A Yui, MC Nawijn, MK Anderson, N Takemoto, RW Hendriks, S Ezoe, S Höflinger, S Nishimura, SI Samson, SY Pai, T Taghon, T Taghon, T Yamagata, TM Schmitt, TN Taghon, Tom Taghon, WS Wise, Y Arinobu   +52 more
core   +2 more sources

GATA-3 Stimulates Proliferation of Endometriotic Cells

Ginekologia Polska, 2019
This study aimed to investigate whether there was a correlation between the expression of GATA binding protein 3 (GATA-3) and the proliferation of endometrium cells from women with endometriosis.Endometrial tissue was collected from 20 women with endometriosis (experimental group) and 10 women without endometriosis (control group).
Peng, Chen, Fang, Ren, Dan-Bo, Wang
openaire   +3 more sources

GATA-3 EXPRESSION IN PERIPHERAL BLOOD LYMPHOCYTES OF PATIENTS WITH BRONCHIAL ASTHMA

Медицинская иммунология, 2014
The aim of the study is to establish the features of expression of GATA-3 in peripheral lymphocytes from bronchial asthma patients (BA). Material and methods.
V. N. Mineev, L. N. Sorokina, M. A. Nyoma, V. I. Trofimov   +3 more
doaj   +1 more source

Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3. [PDF]

PLoS ONE, 2015
Mast cell (MC) degranulation is the foundation of the acute phase of allergic rhinitis (AR). Previously, downregulation of GATA binding protein 3 (GATA-3) was shown to suppress MC activation in an AR mouse model.
Yu-Qin Deng, Ya-Qi Yang, Shui-Bin Wang, Fen Li, Meng-Zhi Liu, Qing-Quan Hua, Ze-Zhang Tao   +6 more
doaj   +1 more source

Clinical significance of T-bet, GATA-3, and Bcl-6 transcription factor expression in bladder carcinoma [PDF]

, 2016
International audienceBackground: The aim of this study was to investigate the clinical significance of three immune cell-related transcription factors, T-bet, GATA-3 and Bcl-6 in bladder cancer in Tunisian patients.Methods: Expression of T-bet, GATA-3 ...
Bahria-Sediki, Islem Ben, Bettaieb, Ali, Chebil, Mohamed, Cherif, Mohamed, El Gaaied, Amel Ben Ammar, Paul, Catherine, Yousfi, Nadhir, Zermani, Rachida   +7 more
core   +3 more sources

Transcription factor GATA‐3 is essential for lens development [PDF]

Developmental Dynamics, 2009
AbstractDuring vertebrate lens development, the anterior, ectoderm‐derived lens vesicle cells differentiate into a monolayer of epithelial cells that retain proliferative potential. Subsequently, they exit the cell cycle and give rise to posterior lens fiber cells that form the lens body.
Maeda, Atsuko, Moriguchi, Takashi, Hamada, Michito, Kusakabe, Manabu, Fujioka, Yuki, Nakano, Takako, Yoh, Keigyou, Lim, Kim-Chew, Engel, James Douglas, Takahashi, Satoru   +9 more
openaire   +3 more sources

Th2/1 Hybrid Cells Occurring in Murine and Human Strongyloidiasis Share Effector Functions of Th1 Cells [PDF]

, 2017
Infections by the soil-transmitted threadworm Strongyloides stercoralis affect 50-100 million people worldwide, predominantly in tropic and sub-tropic regions. Here we assessed the T helper cell phenotypes in threadworm-infected patients and experimental
Afkarian, Allen, Anthony, Anuradha, Bisoffi, Blankenhaus, Breloer, Buonfrate, Cai, Chang, Chiuso-Minicucci, Dawkins, Erbe, Eschbach, Figueiredo, Finkelman, Finkelman, Guo, Guo, Harris, Hegazy, Helmstetter, Ioan-Facsinay, Jenner, Kim, Lohning, Montes, Nouir, Ouyang, Pai, Panzer, Patel, Peine, Pesce, Puthiyakunnon, Quinnell, Rausch, Robinson, Ruano, Ruano, Siddiqui, Snapper, Steinfelder, Strandmark, Szabo, Turner, Turner, Urban, Vadlamudi, Vidarsson, Weatherhead, Yoshimoto, Zheng, Zhu, Zhu   +54 more
core   +3 more sources

Expression of GATA‐3 During Lymphocyte Differentiation and Mouse Embryogenesis [PDF]

Journal of Immunology Research, 1992
The GATA family of C4 zinc‐finger transcription factors has been implicated in tissuespecific gene regulation in birds and mammals. One of the members of this family, GATA‐3, is reportedly expressed specifically in the T‐cell lineage, where it interacts with GATA motifs in the TCR‐αα, TCR‐β/, and TCR‐δ enhancers, thereby controlling the T‐cell ...
Oosterwegel, M.A., Timmerman, J., Leiden, J., Clevers, J.C.   +3 more
openaire   +3 more sources

Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma

Scientific Reports, 2017
Interferon regulatory factor 3 (IRF-3) is widely known for its prompt response against viral infection by activating the interferon system. We previously reported that E2F1, Sp1 and Sp3 regulated transcriptional activity of IRF-3.
Lu-Lu Wang, Zheng-Sen Chen, Wen-Di Zhou, Jin Shu, Xiao-Hua Wang, Rui Jin, Li-Li Zhuang, Mir Alireza Hoda, Hao Zhang, Guo-Ping Zhou   +9 more
doaj   +1 more source