Results 31 to 40 of about 18,813,060 (218)
GATA-3 Expression in all Grades and Different Variants of Primary and Metastatic Urothelial Carcinoma. [PDF]
Naik M +8 more
europepmc +2 more sources
GATA-3-dependent Gene Transcription is Impaired upon HDAC Inhibition. [PDF]
Abstract Purpose: Many peripheral and cutaneous T-cell lymphoma (CTCL) subtypes are poorly responsive to conventional chemotherapeutic agents and associated with dismal outcomes. The zinc finger transcription factor GATA-3 and the transcriptional program it instigates are oncogenic and highly ...
Geng X +9 more
europepmc +3 more sources
GATA-3 Expression in Trophoblastic Tissues [PDF]
Immunohistochemical expression of GATA-3 is seen predominantly in non-neoplastic bladder and breast epithelium and their respective carcinomas; however, data on expression in normal and lesional trophoblastic tissues are limited. Immunohistochemical staining for GATA-3 was assessed in a range of normal/lesional trophoblastic tissues and tumors in the ...
Natalie, Banet +12 more
openaire +3 more sources
GATA-3 locks the door to the B-cell option [PDF]
In this issue of Blood, García-Ojeda et al demonstrate a key mechanism that drives T and B lymphocytes to divergent fates from early in their development.
Rothenberg, Ellen V.
openaire +6 more sources
Mammary like gland adenoma with GATA-3 expression - a benign vulval tumor with mammary differentiation often misdiagnosed as adenocarcinoma [PDF]
Papillary hidradenoma/ mammary-like gland adenoma (MLGA) is a benign glandular tumor of the vulva. It presents as a mass lesion which often undergoes secondary ulceration and bleeding resembling a malignant tumor.
Deval Parekh +3 more
doaj +1 more source
Background GATA binding protein 3 (GATA-3) is one of the six transcription factor family members and is important for glandular development in the breast. Its expression becomes important in breast cancer.
Leymune Parlak, Olcay Kandemir
doaj +1 more source
Gata-3 and mammary cell fate [PDF]
Genomic regulatory networks specify how cellular gene expression responds to external temporal and spatial stimuli, ensuring that correct cell fate decisions are made and the appropriate cell phenotypes are adopted. In mammary epithelial cells, the hierarchy of stem and progenitor cells and the genetically specified program of transcriptional activity ...
Naylor, Matthew J +1 more
openaire +2 more sources
GATA-3 Function in Innate and Adaptive Immunity [PDF]
The zinc-finger transcription factor GATA-3 has received much attention as a master regulator of T helper 2 (Th2) cell differentiation, during which it controls interleukin-4 (IL-4), IL-5, and IL-13 expression. More recently, GATA-3 was shown to contribute to type 2 immunity through regulation of group 2 innate lymphoid cell (ILC2) development and ...
Tindemans, Irma +3 more
openaire +3 more sources
Can GATA3 Immunocytochemistry be Utilized as a Reliable Diagnostic Marker for Metastatic Breast Carcinoma in Cytological Materials? A Comparative Study with Mammaglobin and GCDFP-15 Expression [PDF]
Objective: Cytomorphologic differentiation of metastatic breast carcinoma from non breast metastases in cytological materials can be difficult. Current breast immunocytochemical markers have low sensitivities.
Nesreen H. HAFEZ, HebatAllah M. SHAABAN
doaj +1 more source
Objectives The aim of this study was to evaluate the expression of GCDFP15 and GATA‐binding protein 3 (GATA‐3) in extramammary Paget's disease (EMPD) skin and serum samples and to assess their availability as tumor markers for the diagnosis and ...
Soichiro Kado +7 more
doaj +1 more source

