Results 61 to 70 of about 54,955 (220)

Enforced Expression of GATA-3 Severely Reduces Human Thymic Cellularity [PDF]

The Journal of Immunology, 2001
Abstract Following bone marrow transplantation, patients often suffer from immune incompetence by reduced or late T cell development. Moreover, adult bone marrow stem cells have a lower capacity to generate T cells compared with fetal liver- and umbilical cord blood-derived progenitors.
T, Taghon, M, De Smedt, F, Stolz, M, Cnockaert, J, Plum, G, Leclercq   +5 more
openaire   +2 more sources

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. [PDF]

, 2017
Human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced PSCs (iPSCs), represent potentially unlimited cell sources for clinical applications. Previous studies have suggested that hPSCs may benefit from immune privilege and
Allard, Patrick, Chang, Kai-Wei, Chen, Hsin-Fu, Chou, Wen-Hsi, Ghelfi, Elisa, Ho, Hong-Nerng, Huang, Mei-Chi, Jan, Pey-Shynan, Lin, Shau-Ping, Lu, Chen-Yu, Wu, Chia-Eng, Wu, Fang-Chun, Yu, Chen-Wei   +12 more
core   +1 more source

GATA-3 transcriptional imprinting in Th2 lymphocytes: A mathematical model [PDF]

Proceedings of the National Academy of Sciences, 2002
Immunological memory involves the fast recall of cytokine expression by T helper (Th) lymphocytes. Two distinct profiles of cytokine expression, Th1 and Th2, can be induced by antigen and polarizing signals during activation of naive Th cells and can subsequently be reexpressed on stimulation by antigen alone.
Thomas, Höfer, Holger, Nathansen, Max, Löhning, Andreas, Radbruch, Reinhart, Heinrich   +4 more
openaire   +2 more sources

Metabolic Regulation of Dimethylsulfoniopropionate Cleavage and Dimethyl Sulfide Production in Halomonas sp. D47

Advanced Science, EarlyView.
Dimethylsulfoniopropionate (DMSP) is a major marine organosulfur compound central to climate‐relevant dimethyl sulfide (DMS) production. In Halomonas sp. D47, DMSP catabolism is revealed to be coordinated by two transcriptional regulators, AcuR and AcuZ, which control gene expression by sensing DMSP and its metabolites.
Li‐Yuan Zheng, Wen‐Xin Jiang, Xiao‐Meng Sun, Li Liu, Zhao‐Jie Teng, Hou‐Qi Wang, Wen‐Jing Zhu, Chang Ge, Qi‐Long Qin, Ning‐Hua Liu, Hai‐Yan Cao, Hui‐Hui Fu, Chun‐Yang Li, Jonathan D. Todd, Xiu‐Lan Chen, Yu‐Zhong Zhang, Peng Wang   +16 more
wiley   +1 more source

The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4. [PDF]

PLoS ONE, 2013
The cytoplamic junctional proteins cingulin and paracingulin have been implicated in the regulation of gene expression in different cultured cell models.
Laurent Guillemot, Domenica Spadaro, Sandra Citi   +2 more
doaj   +1 more source

GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo. [PDF]

, 1997
We previously demonstrated that the zinc finger transcription factors GATA-2 and GATA-3 are expressed in trophoblast giant cells and that they regulate transcription from the mouse placental lactogen I gene promoter in a transfected trophoblast cell line.
Engel, J.D. (Douglas), Groskopf, J.C. (John), Grosveld, F.G. (Frank), Linzer, D.I.H. (Daniel), Ma, G.T. (Grace), Orkin, S.H. (Stuart), Roth, M.E. (Matthew), Tsai, F.Y. (Fong-Ying)   +7 more
core   +1 more source

Molecular Genetics of T Cell Development [PDF]

, 2005
T cell development is guided by a complex set of transcription factors that act recursively, in different combinations, at each of the developmental choice points from T-lineage specification to peripheral T cell specialization. This review describes the
Aifantis I, Allen JD, Alvarez JD, Anderson MK, Barndt R, Cooper CL, Durum SK, Fisher RC, Gadina M, Hsiang YH, Hsiang YH, Ishiguro A, Ivanov V, Izon DJ, Kishi H, Kohu K, Mao C, McCracken S, McKercher SR, Mullen AC, Nerlov C, Ohteki T, Rosenbauer F, Rothenberg EV, Schilham MW, Sikes ML, Spain LM, Zhang D-H   +27 more
core   +1 more source

Staging an Experience of Cultural Heritage Preservation: Consumers' Willingness to Pay for Heirloom Rice in the Philippines

Agribusiness, EarlyView.
ABSTRACT The Cordillera Administrative Region in the Philippines is home to terraced rice embedded in centuries of cultural heritage. However, weak market incentives threaten sustained production, jeopardizing indigenous communities' cultural heritage and the in situ biodiversity of rice genetic resources.
Kofi Britwum, Matty Demont
wiley   +1 more source

GATA-3 is involved in the development of serotonergic neurons in the caudal raphe nuclei [PDF]

, 1999
The GATA-3 transcription factor shows a specific and restricted expression pattern in the developing and adult mouse brain. In the present study we investigated the role of GATA-3 in the caudal raphe system, which is known to operate as a modulator of ...
Doorninck, J.H. (Hikke) van, Goedknegt, E. (Erika), Grosveld, F.G. (Frank), Karis, A. (Alar), Rutteman, M. (Mandy), Wees, J. (Jacqueline) van der, Zeeuw, C.I. (Chris) de   +6 more
core