Results 81 to 90 of about 18,813,060 (218)

Fighting viral infections and virus-driven tumors with cytotoxic CD4+ T cells [PDF]

, 2017
CD4+ T cells have been and are still largely regarded as the orchestrators of immune responses, being able to differentiate into distinct T helper cell populations based on differentiation signals, transcription factor expression, cytokine secretion, and
Adhikary, Adhikary, Adhikary, Ahn, Anderson, Annunziato, Appay, Appay, Aslan, Balfour, Battaglia, Baumjohann, Bickham, Bosselut, Britt, Brown, Brown, Brown, Brown, Brown, Bui, Cao, Cao, Cao, Carpenter, Casazza, Chen, Cheroutre, Chiu, Coler, de Souza, Deligeoroglou, Demachi-Okamura, Depil, Devarajan, Di Mitri, Dillon, Draenert, Duftner, Dumitriu, Endo, Enssle, Eshima, Facchinetti, Farrar, Faè, Fishman, Fleischer, Fontenot, Freeman, Fu, Fu, Gamadia, Gao, Garcia-Chagollan, Gasser, Geginat, Gelband, Goonetilleke, Grabowska, Grakoui, Grant, Grant, Groh, Ha, Haigh, Haque, Heaton, Hegde, Heller, Heusinkveld, Hildemann, Hislop, Hohler, Homma, Houser, Hua, Huz, Icheva, James, Jameson, Jeitziner, Johnson, Jones, Jones, Jonjic, Kadish, Kannanganat, Kaufmann, Kayagaki, Kenter, Kenter, Khanolkar, King, King, Kobayashi, Koel, Krensky, Kroesen, Kruger, Kuroda, Lazdina, Li, Libri, Lin, Loewendorf, Long, Long, Long, Long, Luckheeram, Lunemann, MacArthur, Mackay, Magnani, Malnati, Man, Manzke, Marshall, Martorelli, Mattapallil, McKinstry, McMichael, Merlo, Merlo, Metkar, Miamen, Moormann, Morales, Mosmann, Mucida, Munz, Munz, Murphy, Musey, Namekawa, Nemes, Nikiforow, Nixon, Norris, Oestreich, Omiya, O’Shea, Pachnio, Pachnio, Paludan, Pender, Peng, Penna, Piriou, Plata, Porakishvili, Qui, Quigley, Ratto-Kim, Reis, Rentenaar, Rerks-Ngarm, Ressing, Rosenberg, Sacha, Sakaguchi, Sallusto, Sandbulte, Savic, Scherrenburg, Schueller, Schulze zur Wiesch, Schulze Zur Wiesch, Schwartz, Seresini, Seresini, Soghoian, Soghoian, Spaete, Stacey, Steele, Streeck, Stuller, Su, Sun, Tagawa, Takeuchi, Tenzer, Terahara, Tewari, Thursz, Todryk, Tong, Toussirot, Trautmann, Trautmann, Trifari, Tscharke, Turnbull, Ulsenheimer, Vacchio, van de Berg, van den Hende, van Leeuwen, Vasin, Veldhoen, Ventura, Verma, Veronese, Voo, Voo, Vossen, Walker, Walton, Wang, Wang, Welters, Welters, WHO, Wilkinson, Wilson, Wilson, Wintermeyer, Workman, Xie, Xue, Yan, Yewdell, Zaunders, Zaunders, Zheng, Zhou, Zuo, zur Hausen   +229 more
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To Evaluate GATA 3 Positivity in Gallbladder Adenocarcinoma

, 2022
: GATA 3 immunostainis an important immune histo chemical stain used in surgical pathology for the detection of breast and urothelial carcinomas. In the recently published literature, GATA3 immunostain positivity has been reported in gallbladder adenocarcinoma.
Ayma Batool, Aafia Qasim, Zafar, Asma, Chughtai, Akhtar Sohail, Saira Javeed, Ujyara Maryam   +5 more
openaire   +1 more source

Comparison of GATA-3, mammaglobin, GCDFP-15 expression in breast carcinoma in serous effusions: A cell-block micro-array study

Pleura and Peritoneum, 2017
Background GATA-3 is a potential marker for detection of metastatic breast carcinoma, reportedly more sensitive than mammaglobin (MAM) and GCDFP-15.
Mohamed El Hag, Amani Hag, Jennifer P. Ha, C. Michael   +3 more
semanticscholar   +1 more source

Optimizing the GATA-3 position weight matrix to improve the identification of novel binding sites [PDF]

, 2012
BACKGROUND: The identifying of binding sites for transcription factors is a key component of gene regulatory network analysis. This is often done using position-weight matrices (PWMs).
Ilya Ioshikhes, Soumyadeep Nandi
core   +2 more sources

Transcriptional regulation of the human ALDH1A1 promoter by the oncogenic homeoprotein TLX1/HOX11 [PDF]

, 2009
The homeoprotein TLX1, which is essential to spleen organogenesis and oncogenic when aberrantly expressed in immature T cells, functions as a bifunctional transcriptional regulator, being capable of activation or repression depending on cell type and/or ...
Rice, K.L., Heidari, M., Taplin, R., Kees, U.R., Greene, W.K.   +4 more
core   +4 more sources

GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo. [PDF]

, 1997
We previously demonstrated that the zinc finger transcription factors GATA-2 and GATA-3 are expressed in trophoblast giant cells and that they regulate transcription from the mouse placental lactogen I gene promoter in a transfected trophoblast cell line.
Engel, J.D. (Douglas), Groskopf, J.C. (John), Grosveld, F.G. (Frank), Linzer, D.I.H. (Daniel), Ma, G.T. (Grace), Orkin, S.H. (Stuart), Roth, M.E. (Matthew), Tsai, F.Y. (Fong-Ying)   +7 more
core   +1 more source

ScRNA-Seq Analyses Define the Role of GATA3 in iNKT Cell Effector Lineage Differentiation

Cells
While the transcription factor GATA-3 is well-established for its crucial role in T cell development, its specific influence on invariant natural killer T (iNKT) cells remains relatively unexplored.
Tzong-Shyuan Tai, Huang-Yu Yang, Wan-Chu Chuang, Yu-Wen Huang, I-Cheng Ho, Ching-Chung Tsai, Ya-Ting Chuang   +6 more
doaj   +1 more source

GATA-3 is required for early T lineage progenitor development [PDF]

The Journal of Cell Biology, 2009
Most T lymphocytes appear to arise from very rare early T lineage progenitors (ETPs) in the thymus, but the transcriptional programs that specify ETP generation are not completely known. The transcription factor GATA-3 is required for the development of T lymphocytes at multiple late differentiation steps as well as for the development of thymic ...
Hosoya, Tomonori, Kuroha, Takashi, Moriguchi, Takashi, Cummings, Dustin, Maillard, Ivan, Lim, Kim-Chew, Engel, James Douglas   +6 more
openaire   +2 more sources

Dysregulation of junctional adhesion molecule-A via p63/GATA-3 in head and neck squamous cell carcinoma

OncoTarget, 2016
Junctional adhesion molecule-A (JAM-A), which belongs to the IgG superfamily, is a tight junction molecule associated with epithelial and endothelial barrier function.
Takuya Kakuki, M. Kurose, K. Takano, A. Kondoh, Kazufumi Obata, Kazuaki Nomura, Ryo Miyata, Yakuto Kaneko, Takumi Konno, Syunta Takahashi, Tsubasa Hatakeyama, Takayuki Kohno, T. Himi, T. Kojima   +13 more
semanticscholar   +1 more source

Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells [PDF]

, 2016
Innate lymphoid cells (ILCs) patrol environmental interfaces to defend against infection and protect barrier integrity. Using a genetic tuning model, we demonstrate that the signal-dependent transcription factor (TF) STAT5 is critical for accumulation of
Villarino, Alejandro V^, Sciumè, Giuseppe^, Davis, Fred P, Iwata, Shigeru, Zitti, Beatrice, Robinson, Gertraud W, Hennighausen, Lothar, Kanno, Yuka, O'Shea, John J, ^Co-Firs, T.   +9 more
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