Results 51 to 60 of about 493,799 (275)

Spin Gating of Mesoscopic Devices

open access: yes, 2015
Inefficient screening of electric fields in nanoconductors makes electric manipulation of electronic transport in nanodevices possible. Accordingly, electrostatic (charge) gating is routinely used to affect and control the Coulomb electrostatics and ...
Jonson, M., Shekhter, R. I.
core   +1 more source

CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]

open access: yes, 2014
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
core   +2 more sources

The Role of Working Memory Gating in Task Switching: A Procedural Version of the Reference-Back Paradigm

open access: yesFrontiers in Psychology, 2017
Models of working memory (WM) suggest that the contents of WM are separated from perceptual input by a gate, that enables shielding information against interference when closed, and allows for rapid updating when open.
Yoav Kessler
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Feto-Maternal Crosstalk in the Development of the Circadian Clock System

open access: yesFrontiers in Neuroscience, 2021
The circadian (24 h) clock system adapts physiology and behavior to daily recurring changes in the environment. Compared to the extensive knowledge assembled over the last decades on the circadian system in adults, its regulation and function during ...
Mariana Astiz, Henrik Oster
doaj   +1 more source

Ambipolar transport in bulk crystals of a topological insulator by gating with ionic liquid

open access: yes, 2012
We report that the ionic-liquid gating of bulk single crystals of a topological insulator can control the type of the surface carriers and even results in ambipolar transport. This was made possible by the use of a highly bulk-insulating BiSbTeSe2 system
J. Ye   +6 more
core   +1 more source

Flexibility of the N-Terminal mVDAC1 Segment Controls the Channel’s Gating Behavior [PDF]

open access: yes, 2012
Since the solution of the molecular structures of members of the voltage dependent anion channels (VDACs), the N-terminal α-helix has been the main focus of attention, since its strategic location, in combination with its putative conformational ...
Anastasia Salisowski   +8 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Molecular and Evolution In Silico Studies Unlock the h4-HPPD C-Terminal Tail Gating Mechanism

open access: yesBiomedicines
The enzyme 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) is involved in the catabolism of the amino acid tyrosine in organisms such as bacteria, plants, and animals.
Alfonso Trezza   +4 more
doaj   +1 more source

Aquaporins: More Than Functional Monomers in a Tetrameric Arrangement

open access: yesCells, 2018
Aquaporins (AQPs) function as tetrameric structures in which each monomer has its own permeable pathway. The combination of structural biology, molecular dynamics simulations, and experimental approaches has contributed to improve our knowledge of how ...
Marcelo Ozu   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy