Results 61 to 70 of about 136,869 (147)

Estratégia do Programa de Cabo Verde (2010-2014) [PDF]

open access: yes, 2010
O Programa das Pequenas Subvenções do Fundo Mundial do Ambiente às ONGs (GEF SGP) é um programa a nível mundial implementado pelo PNUD e executado administrativamente pelos Escritórios das Nações Unidas para Execução de Projectos, a UNOPS.
PNUD, GEF
core  

The Small GTPase RHO1 Regulates ROS Homeostasis and Differentially Responds to Pathogens Infection via Interaction With Aquaporin TIP1;1 in Nicotiana

open access: yesMolecular Plant Pathology, Volume 27, Issue 9, September 2026.
The RHO1‐TIP1;1 interaction affects the compartmentalization of reactive oxygen species (ROS) in cytoplasm and vacuoles, promotes the accumulation of ROS in cytoplasm, leading to different responses of plant cells to pathogens with different lifestyles.
Bowen Yuan   +10 more
wiley   +1 more source

Functional characterization of GEF-H1 in liver tumorigenesis. [PDF]

open access: yes, 2012
Tsang, Chi Keung."November 2011."Thesis (M.Phil.)--Chinese University of Hong Kong, 2012.Includes bibliographical references (leaves 103-116).Abstracts in English and Chinese.Abstract --- p.I摘要 --- p.IIIAcknowledgement --- p.IVTable of content --- p ...

core  

Characterization of LPS-induced expression of GEF-H1.

open access: yes, 2014
Human pulmonary EC were on 2.8(200 ng/ml). A - Time-dependent expression of GEF-H1 was determined by western blot analysis. Equal protein loading was confirmed by membrane re-probing with β-actin antibody.
Anna A. Birukova (333901)   +6 more
core   +1 more source

The Mechanobiology of Adipocyte Hypertrophy: Cytoskeletal Remodelling as a Driver of Insulin Resistance in Obesity

open access: yesCell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Adipocyte hypertrophy poses an important mechanical challenge—adipocytes can increase in volume up to a thousand‐fold while still maintaining their structural integrity. Although lipid metabolism is well studied, little is known about the cytoskeletal adaptations that are required to accommodate this expansion and the resulting pathological ...
Dhakshmi Sasankan, Renu Mohan
wiley   +1 more source

Enhanced tumor cell killing by ultrasound after microtubule depolymerization

open access: yesBioengineering & Translational Medicine, 2021
Recent studies show that tumor cells are vulnerable to mechanical stresses and undergo calcium‐dependent apoptosis (mechanoptosis) with mechanical perturbation by low‐frequency ultrasound alone.
Aditi Singh   +6 more
doaj   +1 more source

Fostering Women's Political Leadership Through Government Accountability: Evidence From OECD Countries

open access: yesPublic Administration and Development, Volume 46, Issue 3, Page 410-426, August 2026.
ABSTRACT Women remain significantly underrepresented in political leadership worldwide. This study examines how different combinations of government accountability mechanisms enhance women's political representation (WPR) as a pathway to leadership in 30 OECD countries.
Samira Nazar, Seyed Ashkan Zarghami
wiley   +1 more source

A role for RASSF1A in tunneling nanotube formation between cells through GEFH1/Rab11 pathway control

open access: yesCell Communication and Signaling, 2018
Background By allowing intercellular communication between cells, tunneling nanotubes (TNTs) could play critical role in cancer progression. If TNT formation is known to require cytoskeleton remodeling, key mechanism controlling their formation remains ...
Fatéméh Dubois   +12 more
doaj   +1 more source

Nucleic Acid Therapeutics for “Undruggable” Cancer Targets: Mechanisms, Challenges, and Prospects

open access: yesAdvanced Science, Volume 13, Issue 36, 29 June 2026.
Nucleic acid therapeutics bypass the structural limitations of conventional drugs by targeting mRNA rather than proteins. This review examines how antisense oligonucleotides, siRNAs, miRNAs, aptamers, and mRNA vaccines intervene against historically undruggable oncoproteins including Ras, MYC, and p53, highlighting mechanistic advances, delivery ...
Feng Xu   +6 more
wiley   +1 more source

The Role and Regulation of the Exchange Factor GEF-H1 in Tubular Cells [PDF]

open access: yes, 2014
The Rho family small GTPases are key regulators of the cytoskeleton, through which they impact and control many vital cellular functions, including growth, vesicle trafficking, intercellular junctions, transepithelial transport, migration, and gene ...
Waheed, Faiza
core   +1 more source

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