Results 1 to 10 of about 7,371,567 (249)
Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer. [PDF]
, 2013 The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the induction of pluripotency in terminally differentiated somatic cells.
Agaimy, Abbas +14 more
core +19 more sources
Gene Amplification in Tumor Cells: Developed De Novo or Adopted from Stem Cells
Cells, 2022 Gene amplifications have been known for several decades as physiological processes in amphibian and flies, e.g., during eggshell development in Drosophila and as part of pathological processes in humans, specifically in tumors and drug-resistant cells ...
Ulrike Fischer, Eckart Meese
doaj +1 more source
Microbiology Spectrum, 2022 Enhanced levels of resistance to antibiotics arising from amplification of an antibiotic resistance gene that impact therapeutic options are increasingly observed. Amplification can also disclose novel phenotypes leading to treatment failure.
Christopher J. Harmer +4 more
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Chromothripsis drives the evolution of gene amplification in cancer
Nature, 2020 Focal chromosomal amplification contributes to the initiation of cancer by mediating overexpression of oncogenes1–3, and to the development of cancer therapy resistance by increasing the expression of genes whose action diminishes the efficacy of anti ...
Ofer Shoshani +14 more
semanticscholar +1 more source
Induction of Gene Amplification Contribute to Sulfonamide Resistance in Proteus mirabilis [PDF]
مجلة التربية والعلم, 2007 Thirty Isolates of Proteus mirabilis from different clinical sources (Urine, Bum, Ear, and Wounds) were recovered. All isolates were subjected to the series of confirming tests to insure that these isolates are Proteus mirabilis, which identified ...
Zeerak Abdulrahman
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Definitions, 2020 Gene amplification is an increase in the number of copies of a gene sequence. Cancer cells sometimes produce multiple copies of genes in response to signals from other cells or their environment. The term also can refer to polymerase chain reaction (PCR),
semanticscholar +1 more source
Clinical and imaging features of a pedigree with spinocerebellar ataxia type 6
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 doi：10.3969/j.issn.1672⁃6731.2021.06 ...
YANG Yun⁃peng +2 more
doaj +1 more source
Viral load could be an important determinant for fomites based transmission of viral infections
Journal of Family Medicine and Primary Care, 2021 Background and Objective: Fomites are common sources of transmission of certain infections. Infectious pathogens, such as viruses known to cause respiratory tract infections, are common examples of being transmitted by fomites.
Dhirendra P Singh +6 more
doaj +1 more source
Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment
eLife, 2020 Evolutionary innovations allow populations to colonize new ecological niches. We previously reported that aerobic growth on citrate (Cit+) evolved in an Escherichia coli population during adaptation to a minimal glucose medium containing citrate (DM25 ...
Zachary D Blount +11 more
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Microorganisms, 2023 Locus-specific gene amplification and genome-wide endoreplication generate the elevated copy number of ribosomal DNA (rDNA, 9000 C) and non-rDNA (90 C) chromosomes in the developing macronucleus of Tetrahymena thermophila.
Xiangzhou Meng +2 more
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