Results 31 to 40 of about 8,013,600 (393)
Zhongliu Fangzhi Yanjiu, 2018 Objective To detect the amplification of HER2 gene by fluorescence in situ hybridization(FISH), and explore the correlation between HER2 gene amplification and clinicopathological characteristics. Methods We collected 325 cases of breast cancer with HER2(
ZHANG Mingshuai +5 more
doaj +1 more source
Clinical and imaging features of a pedigree with spinocerebellar ataxia type 6
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 doi：10.3969/j.issn.1672⁃6731.2021.06 ...
YANG Yun⁃peng +2 more
doaj +1 more source
circRNA meets gene amplification [PDF]
Non-coding RNA Investigation, 2018 Lung cancer remains the most common cause of cancer related death among both males and females globally accounting for 1.69 million deaths in 2015 (1). Of the different types of lung cancer, lung adenocarcinoma (LAC) is the most common (2). Given the prevalence and lethality of lung cancer the need to elucidate the mechanisms of this disease and to ...
Hisashi Tanaka +2 more
openaire +2 more sources
NELFE-Dependent MYC Signature Identifies a Unique Cancer Subtype in Hepatocellular Carcinoma. [PDF]
, 2019 The MYC oncogene is dysregulated in approximately 30% of liver cancer. In an effort to exploit MYC as a therapeutic target, including in hepatocellular carcinoma (HCC), strategies have been developed on the basis of MYC amplification or gene ...
Bodzin, Adam S. +9 more
core +3 more sources
Cellular Oncology, 2006 Deregulation of cell cycle control is a hallmark of cancer. The primary cyclins (A, B1, D1, D3 and E) are crucial for cell cycle progression. Secondary cyclins (C and H) have putative indirect effects on cell cycle propulsion and are not previously ...
A. Husdal, G. Bukholm, I. R. K. Bukholm
doaj +1 more source
Frontiers in Pharmacology, 2019 This study investigates the protein expression of C-MYC, BCL-2, and BCL-6 in diffuse large B-cell lymphoma (DLBCL) and their relationship with genetic abnormalities.
YunXiang Zhang +7 more
doaj +1 more source
Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8a1 and human ch13q34 [PDF]
, 2007 Serial analysis of gene expression from aggressive mammary tumors derived from transplantable p53 null mouse mammary outgrowth lines revealed significant up-regulation of Tfdp1 (transcription factor Dp1), Lamp1 (lysosomal membrane glycoprotein 1) and ...
Abba, Martín Carlos +8 more
core +1 more source
Archives of Medical Science, 2019 Introduction Identifying target oncogenic alterations in lung cancer represents a major development in disease management. We examined the association of fibroblast growth factor receptor 1 (FGFR1) gene amplification with pathological characteristics and
Jian-Long Miao +3 more
doaj +1 more source
High MYC mRNA expression is more clinically relevant than MYC DNA amplification in triple-negative breast cancer [PDF]
, 2019 DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC).
Dasgupta, Subhamoy +6 more
core +2 more sources
Viral load could be an important determinant for fomites based transmission of viral infections
Journal of Family Medicine and Primary Care, 2021 Background and Objective: Fomites are common sources of transmission of certain infections. Infectious pathogens, such as viruses known to cause respiratory tract infections, are common examples of being transmitted by fomites.
Dhirendra P Singh +6 more
doaj +1 more source