Results 141 to 150 of about 2,697,950 (180)

Vascular endothelial growth factor-A gene electrotransfer promotes angiogenesis in a porcine model of cardiac ischemia. [PDF]

Gene Ther, 2016
Bulysheva AA, Hargrave B, Burcus N, Lundberg CG, Murray L, Heller R.   +5 more
europepmc   +1 more source

Comparative Oncology of Companion Animals. [PDF]

Vet Sci
Faustino-Rocha AI, Oliveira PA, Gil da Costa RM.   +2 more
europepmc   +1 more source

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Gene Electrotransfer

2021
Richard Heller
exaly   +2 more sources

Controlled Systemic Release of Interleukin-12 After Gene Electrotransfer to Muscle for Cancer Gene Therapy Alone or in Combination With Ionizing Radiation in Murine Sarcomas

Journal of Gene Medicine, 2009
Background: The present study aimed to evaluate the antitumor effectiveness of systemic interleukin (IL)-12 gene therapy in murine sarcoma models, and to evaluate its interaction with the irradiation of tumors and metastases.
Urska Kamensek, Maja Cemazar, Darja Pavlin   +2 more
exaly   +2 more sources

The Role of Electrophoresis in Gene Electrotransfer

Journal of Membrane Biology, 2010
Gene electrotransfer is an established method for gene delivery which uses high-voltage pulses to increase the permeability of a cell membrane and enables transfer of genes. Poor plasmid mobility in tissues is one of the major barriers for the successful use of gene electrotransfer in gene therapy.
Mojca Pavlin
exaly   +3 more sources

Duration and Level of Transgene Expression After Gene Electrotransfer to Skin in Mice

Gene Therapy, 2010
In development of novel vaccines, attention is drawn to DNA vaccinations. They are heat stable and can be easily produced. Gene electrotransfer is a simple and nonviral means of transferring DNA to cells and tissues and is attracting increasing interest.
Julie Gehl, J Eriksen
exaly   +2 more sources

Gene Electrotransfer of IL-2 and IL-12 Plasmids Effectively Eradicated Murine B16.F10 Melanoma [PDF]

Bioelectrochemistry, 2021
Gene therapy has become an important approach for treating cancer, and electroporation represents a technology for introducing therapeutic genes into a cell. An example of cancer gene therapy relying on gene electrotransfer is the use of immunomodulatory
Masa Omerzel, Maria Mastrodonato, Maja Cemazar   +2 more
exaly   +2 more sources

The Role of Electrically Stimulated Endocytosis in Gene Electrotransfer

Bioelectrochemistry, 2012
Gene electrotransfer is an established method for transfer of genes into cells, however, the mechanism of transfer of DNA across the cell membrane is still not known. Some studies suggest that DNA is translocated through membrane pores while others propose that DNA enters the cell via electro-endocytosis, but no direct observation was performed.
Mojca Pavlin, Maša Kandušer, Gorazd Pucihar   +2 more
exaly   +3 more sources