Results 131 to 140 of about 2,519,482 (174)

Recellularized human dermis for testing gene electrotransfer ex vivo. [PDF]

open access: yesBiomed Mater, 2016
Bulysheva AA   +5 more
europepmc   +1 more source

Electrotransfer as a Non Viral Method of Gene Delivery

open access: yesCurrent Gene Therapy, 2007
Over the last few decades, various vectors have been developed in the field of gene therapy. There still exist a number of important unresolved problems associated with the use of viral as well as non viral vectors. These techniques can suffer from secondary toxicity or low gene transfer efficiency.
Favard, Cyril   +2 more
openaire   +4 more sources
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The role of electrically stimulated endocytosis in gene electrotransfer

Bioelectrochemistry, 2012
Gene electrotransfer is an established method for transfer of genes into cells, however, the mechanism of transfer of DNA across the cell membrane is still not known. Some studies suggest that DNA is translocated through membrane pores while others propose that DNA enters the cell via electro-endocytosis, but no direct observation was performed.
Mojca Pavlin   +2 more
exaly   +3 more sources

Drug and Gene Electrotransfer in Cancer Therapy

open access: yes, 2015
Drug and gene delivery by electroporation is gaining increasing momentum, in particular delivery of chemotherapeutic agents (electrochemotherapy) is now routinely used in many cancer centers, and gene therapy is in clinical trials. Gene therapy using electrotransfer offers the possibility to create a localized area hosting the transgene, with ...
Julie Gehl, Gehl, Julie
openaire   +3 more sources

In vivo gene expression: DNA electrotransfer.

open access: yesCurrent opinion in molecular therapeutics, 2003
The use of electric pulses to deliver therapeutic molecules to tissues and organs in vivo is a rapidly growing field of research. Electrotransfer can be used to deliver a wide range of potentially therapeutic agents, including drugs, proteins, oligonucleotides, RNA and DNA.
Trezise, A. E.   +3 more
openaire   +4 more sources

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