Results 21 to 30 of about 261,824 (309)

Comprehensive information-based differential gene regulatory networks analysis (CIdrgn): Application to gastric cancer and chemotherapy-responsive gene network identification.

open access: yesPLoS ONE, 2023
Biological condition-responsive gene network analysis has attracted considerable research attention because of its ability to identify pathways or gene modules involved in the underlying mechanisms of diseases.
Heewon Park, Seiya Imoto, Satoru Miyano
doaj   +2 more sources

Mutational robustness of gene regulatory networks.

open access: yesPLoS ONE, 2012
Mutational robustness of gene regulatory networks refers to their ability to generate constant biological output upon mutations that change network structure.
Aalt D J van Dijk   +2 more
doaj   +1 more source

Conserved non-coding regulatory signatures in Arabidopsis co-expressed gene modules. [PDF]

open access: yesPLoS ONE, 2012
Complex traits and other polygenic processes require coordinated gene expression. Co-expression networks model mRNA co-expression: the product of gene regulatory networks.
Jacob B Spangler   +4 more
doaj   +1 more source

Introduction to gene regulatory networks [PDF]

open access: yesProceedings of the Genetic and Evolutionary Computation Conference Companion, 2015
Gene regulatory networks are a central mechanism in the regulation of gene expression in all living organisms? cells. Their functioning is nowadays very well understood: they are based on the production of proteins enhanced or inhibited by other proteins inside and outside the cells. This produces a complex dynamics with which, with the exact same DNA,
Sylvain Cussat-Blanc, Wolfgang Banzhaf
openaire   +1 more source

Gene regulatory networks for development [PDF]

open access: yesProceedings of the National Academy of Sciences, 2005
The genomic program for development operates primarily by the regulated expression of genes encoding transcription factors and components of cell signaling pathways. This program is executed by cis-regulatory DNAs (e.g., enhancers and silencers) that control gene expression.
Levine, Michael, Davidson, Eric H.
openaire   +3 more sources

Supervised inference of gene-regulatory networks

open access: yesBMC Bioinformatics, 2008
Background Inference of protein interaction networks from various sources of data has become an important topic of both systems and computational biology.
Vohradsky Jiri, To Cuong C
doaj   +1 more source

Constructing gene regulatory networks using epigenetic data

open access: yesnpj Systems Biology and Applications, 2021
The biological processes that drive cellular function can be represented by a complex network of interactions between regulators (transcription factors) and their targets (genes).
Abhijeet Rajendra Sonawane   +3 more
doaj   +1 more source

Model Checking Gene Regulatory Networks [PDF]

open access: yes, 2015
19 pages, 20 references, 4 ...
Mirco Giacobbe   +5 more
openaire   +3 more sources

Evolution of evolvability in gene regulatory networks. [PDF]

open access: yesPLoS Computational Biology, 2008
Gene regulatory networks are perhaps the most important organizational level in the cell where signals from the cell state and the outside environment are integrated in terms of activation and inhibition of genes.
Anton Crombach, Paulien Hogeweg
doaj   +1 more source

Inferring disease progression and gene regulatory networks from clinical transcriptomic data using PROB_R

open access: yesSTAR Protocols, 2022
Summary: Due to a lack of explicit temporal information, it can be challenging to infer gene regulatory networks from clinical transcriptomic data.
Zhaorui Dong, Xiaoqiang Sun
doaj   +1 more source

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