Results 41 to 50 of about 222,752 (301)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Gifted student in the reality of the polish school

Lubelski Rocznik Pedagogiczny, 2019
The potential of gifted people is a significant resource for every community. That is why it is important that all of the participants of educational process are aware of the categories “abilities” and “gifted student” and their value.
Agnieszka Bochniarz, Anna Grabowiec
doaj   +1 more source

Gifted Students' Purpose in Life [PDF]

Universal Journal of Educational Research, 2018
The aim of the present study is to determine gifted students’ purpose in life via interview in Turkey. Looking at the world population, it is seen that the proportion of gifted children is 2.5-3%. This rate does not change according to the countries of the world. Detection of gifted students is difficult and specific.
Mertol, Hüseyin, Çelik, Nur Demirbaş
openaire   +2 more sources

"Student voice: : perceptions of the Gifted Kids Programme alumni 2000-2007 : a thesis presented in partial fulfillment of the requirements for the degree of Master in Education at Massey University [PDF]

, 2009
Whilst there is some international research available regarding withdrawal programmes and out-of-school options for gifted students, there is little information internationally or nationally surrounding a withdrawal model that students can attend over an
Clark, Deborah
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

A Nation Deceived: How Schools Hold Back America's Brightest Students, Volume II [PDF]

, 2004
Provides a comprehensive review of research on the academic acceleration of gifted ...
Miraca U. M. Gross, Nicholas Colangelo, Susan G. Assouline   +2 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

THE IMPACT OF THE CARBON BORDER ADJUSTMENT MECHANISM (CBAM) ON EXPORT ACTIVITIES INTO THE EU MARKET

Tạp chí Khoa học
This study clarifies the impact of the carbon border adjustment mechanism (CBAM) on the export activities of enterprises that produce six main affected industrial products: iron and steel, cement, fertilizer, aluminium, electricity, and hydrogen ...
Nguyen Thi Lan Anh, Pham Quang Vu, Do Hong Quan, Tran Thanh Tuong, Nguyen Thanh Vinh, Cao Ngoc Diep   +2 more
doaj   +1 more source

Nurturing talent through curriculum integration [PDF]

, 2007
In this paper I discuss the benefits of curriculum integration for gifted and talented students in the regular classroom setting. Although this approach to curriculum delivery enhances learning for all learners, the focus of this article is the gifted ...
Brough, Chris Jane
core   +1 more source