Ginkgetin Alleviates Doxorubicin-Induced Heart Failure by Regulating Mitochondrial Dysfunction Through the AMPK/Sirt1/NF-κB Signaling Pathway [PDF]
Balkan Medical JournalBackground: Heart failure (HF) represents the terminal stage of many cardiovascular diseases. Doxorubicin (DOX) can induce HF through oxidative stress (OS), inflammation, and apoptosis.
Yanfu Wang +5 more
doaj +2 more sources
ROS-responsive, brain- and M1 microglia-targeting modified ginkgetin-loaded smart liposomes ameliorate cerebral ischemia by HIF-1α-mediated negative regulation of microglia pyroptosis [PDF]
Materials Today BioIschemic stroke triggers a cascade of mitochondrial dysfunction, oxidative stress, neuroinflammation, and pyroptosis, ultimately leading to neuronal injury and neurological deficits. Therapeutic efficacy is often limited by inadequate blood–brain barrier
Xueyuan Li +19 more
doaj +2 more sources
Ginkgetin reverses cisplatin resistance in cervical cancer by regulating the Nrf2/HO-1 signaling pathway to induce ferroptosis [PDF]
Scientific ReportsThis study investigates whether Ginkgetin(GK) reverses cisplatin(DDP) resistance in cervical cancer cells by modulating the Nrf2/HO-1 signaling axis to induce ferroptosis, and preliminarily elucidates its underlying mechanisms.
Fei Wang +3 more
doaj +2 more sources
Antifungal Activities of The Extracts From Some Tropical and Temperate Woods [PDF]
Jurnal Manajemen Hutan Tropika, 2011 Empat flavonoids (Sciadopitysin) (1), Ginkgetin (2), Ishorhamnetin (3), dan Quercetin (4), dua Texanes (Taxinine) (5) dan Taxol (6), dan Phenylisoserine methyl ester (7) dapat diisolasi dari Taxus cuspadata var. nana.
Tata Darma +4 more
doaj +4 more sources
Rapid Screening and Structural Characterization of Antioxidants from the Extract of Selaginella doederleinii Hieron with DPPH-UPLC-Q-TOF/MS Method [PDF]
International Journal of Analytical Chemistry, 2015 2,2-Diphenyl-1-picrylhydrazyl-ultra-high performance liquid chromatography-Q-time-of-flight mass spectrometry (DPPH-UPLC-Q-TOF/MS), as a rapid and efficient means, now was used for the first time to screen antioxidants from Selaginella doederleinii.
Gang Wang +3 more
doaj +4 more sources
A Highly Adaptable Hydrogen Bond Re-Orientation (HyBRO) Strategy for Multiscale Vasculature Fabrication. [PDF]
Adv MaterA novel hydrogen bond re‐orientation (HyBRO) strategy enables three‐dimensional (3D) printing of vascular microchannel networks with high accuracy. By switching sacrificial material interactions with nonsolvents, HyBRO prevents swelling and deformation, enabling accurate hierarchical channels spanning a tenfold size range.
Liao Z +5 more
europepmc +2 more sources
Mechanism of action of the antiherpesvirus biflavone ginkgetin [PDF]
Antimicrobial Agents and Chemotherapy, 1992 Screening of plant extracts found that a biflavone from Cephalotaxus drupacea, which was found to be ginkgetin, is active against herpes simplex virus type 1 (HSV-1). This compound caused dose-dependent inhibition of virus replication with a 50% cytotoxic activity at 12.8 micrograms/ml and 50% anti-HSV-1 activity at 0.91 micrograms/ml, the therapeutic ...
K, Hayashi, T, Hayashi, N, Morita
openaire +2 more sources
Ginkgo biloba derivative ginkgetin inhibits breast cancer growth by regulating the miRNA-122-5p/GALNT10 axis [PDF]
Chinese Medical JournalAqu Alu +10 more
doaj +2 more sources
Ginkgetin aglycone exerts anti-osteoporotic effect via regulation of NOX4/Akt/PI3K pathway [PDF]
, 2021 Purpose: To investigate the protective effect of Ginkgetin aglycone (GA) on ovariectomy-induced osteoporosis in rats, as well as the mechanism of action involved.
Dai, Min +3 more
core +2 more sources
Novel Antibiofilm Inhibitor Ginkgetin as an Antibacterial Synergist against Escherichia coli
International Journal of Molecular Sciences, 2022 As an opportunistic pathogen, Escherichia coli (E. coli) forms biofilm that increases the virulence of bacteria and antibiotic resistance, posing a serious threat to human and animal health. Recently, ginkgetin (Gin) has been discovered to have antiinflammatory, antioxidant, and antitumor properties.
Yubin Bai +6 more
openaire +2 more sources