Antiallergic Activity of Ginsenoside Rh2
Biological & Pharmaceutical Bulletin, 2003 The antiallergic activities of ginsenosides, which were isolated from acid-treated ginseng (Panax ginseng, Araliaceae), and their metabolites by human intestinal bacteria were measured. Ginsenoside Rh2, which is a main metabolite, had the most potent inhibitory activity on beta-hexosaminidase release from RBL-2H3 cells and in the passive cutaneous ...
Eun-Kyung, Park +4 more
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AMP-activated protein kinase determines apoptotic sensitivity of cancer cells to ginsenoside-Rh2
Journal of Ginseng Research, 2014 Ginseng saponins exert various important pharmacological effects with regard to the control of many diseases, including cancer. In this study, the anticancer effect of ginsenosides on human cancer cells was investigated and compared.
Min-Jung Kim +6 more
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Photoluminescent And Self-Assembled Hyaluronic Acid-Zinc Oxide-Ginsenoside Rh2 Nanoparticles And Their Potential Caspase-9 Apoptotic Mechanism Towards Cancer Cell Lines [PDF]
, 2019 Background: Zinc oxide nanoparticles (ZnO NPs) are used in modern cancer therapy based on their specific target, efficacy, low toxicity and biocompatibility.
Castro-Aceituno, Veronica +8 more
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Journal of Ginseng Research, 2017 Ginsenoside Rh2 (G-Rh2) is a ginseng saponin that is widely investigated because of its remarkable antitumor activity. However, the molecular mechanism by which (20S) G-Rh2 triggers its functions and how target animals avoid its cytotoxic action remains largely unknown.Phage display was used to screen the human targets of (20S) G-Rh2.
Lin, Yingjia +4 more
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Panax ginseng has no effect on indices of glucose regulation following acute or chronic ingestion in healthy volunteers [PDF]
, 2009 In the absence of effective pharmacotherapy for diabetes there has been an increase in the use of, and research into, alternative treatment strategies. These include exercise, dietary interventions and the use of supplements including extracts of ginseng.
Andrew B. Scholey +8 more
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How Does Ginsenoside Rh2 Mitigate Adipogenesis in Cultured Cells and Obese Mice?
Molecules, 2020 Ginsenoside Rh2, an intermediate metabolite of ginseng, but not naturally occurring, has recently drawn attention because of its anticancer effect. However, it is not clear if and how Rh2 inhibits preadipocytes differentiation.
Longyun Zhang +2 more
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MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy [PDF]
, 2015 In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while ...
Feng, Y +4 more
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A stereo-selective growth inhibition profile of ginsenoside Rh2 on human colon cancer cells
CyTA - Journal of Food, 2019 We compared the stereo-selective growth inhibition effects of purified enantiomeric pairs of ginsenoside Rh2 (20(S)-ginsenoside Rh2 and 20(R)-ginsenoside Rh2) on human colon cancer cells in vitro with non-invasive real-time cellular analysis. When 50 μM,
Yunju Jeong +3 more
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Selected ginsenosides of the prptopanaxdiol series are novel positive allosteric modulators of P2X7 receptors [PDF]
, 2015 Background and Purpose The P2X7 receptor is an ATP-gated ion channel predominantly expressed in immune cells and plays a key role in inflammatory processes.
Adinolfi +48 more
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Ginsenoside Rh2 Reduces Ischemic Brain Injury in Rats
Biological and Pharmaceutical Bulletin, 2004 Ginseng was incubated under mildly acidic conditions and its inhibitory effect on a rat ischemia-reperfusion model was investigated. When ginseng was treated with 0.1% hydrochloric acid at 60 degrees C, its protopanaxadiol saponins were transformed to diasteromeric ginsenoside Rg3 and Delta20-ginsenoside Rg3.
Eun-Kyung, Park +4 more
openaire +3 more sources