Results 51 to 60 of about 3,001 (186)

Data for: Oriented efficient biosynthesis of rare ginsenoside Rh2 from PPD by compiling UGT-Yjic mutant with sucrose synthase [PDF]

, 2019
Ginsenoside Rh2 (3β-O-Glc-protopanaxadiol), a trace but an important pharmacological component of ginseng, has exhibited excellent medicinal potential. Many studies have found that the synthesis of Rh2 by UDP-glucosyltransferase (UGT) is an alternative ...
He, B (via Mendeley Data)
core   +3 more sources

Ginsenoside Rh2 Reduces Ischemic Brain Injury in Rats

Biological and Pharmaceutical Bulletin, 2004
Ginseng was incubated under mildly acidic conditions and its inhibitory effect on a rat ischemia-reperfusion model was investigated. When ginseng was treated with 0.1% hydrochloric acid at 60 degrees C, its protopanaxadiol saponins were transformed to diasteromeric ginsenoside Rg3 and Delta20-ginsenoside Rg3.
Park, Eun-Kyung, Choo, Min-Kyung, Oh, Jin Kyung, Ryu, Jong Hoon, Kim, Dong-Hyun   +4 more
openaire   +3 more sources

The Octyl Ester of Ginsenoside Rh2 Induces Lysosomal Membrane Permeabilization via Bax Translocation [PDF]

, 2016
Ginsenoside Rh2 is a potential pharmacologically active metabolite of ginseng. Previously, we have reported that an octyl ester derivative of ginsenoside Rh2 (Rh2-O), has been confirmed to possess higher bioavailability and anticancer effect than Rh2 in ...
Fang Chen, Yong Sun, Han Peng, Jiang-Ning Hu, Bing Zhang, Zeng-Xing Xiong, Ze-Yuan Deng   +6 more
core   +1 more source

Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells

Frontiers in Pharmacology, 2019
20(S)-ginsenoside Rh2 (Rh2), a well-known protopanaxadiol-type ginsenoside from Panax ginseng has especially gained attention for its anticancer activities on various types of human cancer cells.
Ji Zhang, Weibo Li, Qiaoyun Yuan, Jing Zhou, Jianmei Zhang, Yufeng Cao, Guangbo Fu, Weicheng Hu   +7 more
doaj   +1 more source

Immuno-Enhancing Effect of Ginsenoside Rh2 Liposomes on Foot-and-Mouth Disease Vaccine [PDF]

, 2023
The adjuvant is essential for vaccines because it can enhance or directly induce a strong immune response associated with vaccine antigens. Ginsenoside Rh2 (Rh2) had immunomodulatory effects but was limited by poor solubility and hemolysis. In this study,
Xinzhu Wang (1575541), Fuzheng Ren (3103824), Xuanyu Wang (3879340), Hui Liu (33624), Liusiqi Tang (17467556), Saiya Miao (17467550), Qiufang Jing (17467553), Wenyun Zheng (149784)   +7 more
core   +1 more source

Enhanced anti-glioma activity of annonaceous acetogenins based on a novel liposomal co-delivery system with ginsenoside Rh2. [PDF]

Drug Deliv
Annonaceous acetogenins (ACGs) have potent anti-tumor activity, and the problems of their low solubility, hemolysis, and in vivo delivery have been solved by encapsulation into nanoparticles.
Ao H, Song H, Li J, Wang X.
europepmc   +4 more sources

Assessment of a New Ginsenoside Rh2 Nanoniosomal Formulation for Enhanced Antitumor Efficacy on Prostate Cancer: An in vitro Study

Drug Design, Development and Therapy, 2020
Hadi Zare-Zardini,1– 3 Ashraf Alemi,4 Asghar Taheri-Kafrani,5 Seyed Ahmad Hosseini,6 Hossein Soltaninejad,7,8 Amir Ali Hamidieh,9 Mojtaba Haghi Karamallah,10 Majid Farrokhifar,11 Mohammad Farrokhifar12 1Hematology and Oncology Research Center ...
Zare-Zardini H, Alemi A, Taheri-Kafrani A, Hosseini SA, Soltaninejad H, Hamidieh AA, Haghi Karamallah M, Farrokhifar M, Farrokhifar M   +8 more
doaj  

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source

Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells

World Journal of Gastroenterology, 2013
To investigate the effects of ginsenoside Rh2 on the human pancreatic cancer cell line Bxpc-3.The human pancreatic cancer cell line Bxpc-3 was cultured in vitro and treated with or without ginsenoside Rh2. Growth rates for Bxpc-3 cells were assessed by methyl thiazolyl tetrazolium (MTT) and colony formation assays.
Xi-Ping, Tang, Guo-Du, Tang, Chun-Yun, Fang, Zhi-Hai, Liang, Lu-Yi, Zhang   +4 more
openaire   +2 more sources

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source