Results 51 to 60 of about 2,941 (150)
, 2017 Background: Ginsenoside Rh2 (G-Rh2) is a ginseng saponin that is widely investigated because of its remarkable antitumor activity. However, the molecular mechanism by which (20S) G-Rh2 triggers its functions and how target animals avoid its cytotoxic ...
Yingjia Lin +4 more
core +1 more source
Vacuolization as a Novel Approach to Cancer Therapy
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak +9 more
wiley +1 more source
Study on Antidepressant Activity of Pseudo-Ginsenoside HQ on Depression-Like Behavior in Mice
Molecules, 2019 Suppressive effects of ginsenoside Rh2 (Rh2), (24R)-pseudo-ginsenoside HQ (R-PHQ), and (24S)-pseudo-ginsenoside HQ (S-PHQ) against lipopolysaccharide (LPS)-induced depression-like behavior were evaluated using the forced swimming test (FST) and tail ...
Li-xue Chen +9 more
doaj +1 more source
Diversity of Ginsenoside Profiles Produced by Various Processing Technologies
Molecules, 2020 Ginseng is a traditional medicinal herb commonly consumed world-wide owing to its unique family of saponins called ginsenosides. The absorption and bioavailability of ginsenosides mainly depend on an individual’s gastrointestinal bioconversion abilities.
Xiang Min Piao +9 more
doaj +1 more source
Cancer Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background Bladder cancer (BCa) is the most common and representative type of adult urinary tract urothelial cancer, characterized by high incidence and mortality rates. It has become a major disease threatening public health, highlighting the urgent need for the development of comprehensive treatment strategies, including traditional Chinese ...
Di Liu, Qing‐Yu Zhang
wiley +1 more source
Food Frontiers, Volume 7, Issue 3, May 2026.This review aims to provide a comprehensive understanding of the therapeutic potential of bioactive anticancer phytoconstituents in Panax ginseng, including their clinical aspects and SAR, thereby fostering the development of newer anticancer compounds for cancer management.
Akrit Verma +2 more
wiley +1 more source
Journal of Pharmacopuncture, 2008 Objectives : The aim of this experiment is to provide an differentiation of ginseng, red ginseng, cultivated wild ginseng(CWG), and red wild ginseng(RWG) through component analysis using HPLC(High Performance Liquid Chromatography, hereafter HPLC ...
Jang Ho, Lee +2 more
doaj +1 more source
Targeting Autophagy in Ovarian Cancer: The Emerging Role of Ginsenosides
Cancer Medicine, Volume 15, Issue 3, March 2026.ABSTRACT Background Ovarian cancer, the third most prevalent gynecological malignancy, is frequently diagnosed at an advanced stage owing to its asymptomatic early progression. Despite the application of conventional therapies, clinical management remains limited by adverse effects and the development of drug resistance.
Yuxin Guo +4 more
wiley +1 more source
, 2019 Ginsenoside Rh2 (3β-O-Glc-protopanaxadiol), a trace but an important pharmacological component of ginseng, has exhibited excellent medicinal potential. Many studies have found that the synthesis of Rh2 by UDP-glucosyltransferase (UGT) is an alternative ...
He, B (via Mendeley Data)
core +2 more sources
Bioactive Materials, 2022 Osteosarcoma is a refractory bone disease in young people that needs the updating and development of effective treatment. Although nanotechnology is widely applied in cancer therapy, poor targeting and inadequate efficiency hinder its development.
Liwen Fu +4 more
doaj +1 more source