Results 61 to 70 of about 3,771 (207)

American ginseng modulates pancreatic beta cell activities [PDF]

, 2007
The mechanism of the beneficial effects of Panax quinquefolius (Xiyangshen, American ginseng) on diabetes is yet to be elucidated. Recent studies show that Panax quinquefolius increases insulin production and reduces the death of pancreatic beta cells ...
Zonggui Wu, John Luo, Luguang Luo
core   +1 more source

Advances in Ginsenosides [PDF]

, 2022
This book collected recent innovative research and review articles on analytical techniques, production protocols, biotechnological tools, and new insights into bioactivities of ginsenosides including the effects on epithelial-mesenchymal transition ...

core   +1 more source

Targeting CHEK1: Ginsenosides-Rh2 and Cu2O@G-Rh2 nanoparticles in thyroid cancer

Cell Biology and Toxicology
Thyroid cancer (THCA) is an increasingly common malignant tumor of the endocrine system, with its incidence rising steadily in recent years. For patients who experience recurrence or metastasis, treatment options are relatively limited, and the prognosis is poor. Therefore, exploring new therapeutic strategies has become particularly urgent. This study
Wang, Lidong, Wu, Xin, Wang, XinLu, Dong, Meng, Zhang, Hao, Zhao, Pengfei   +5 more
openaire   +2 more sources

Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7 [PDF]

, 2019
P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens such as Mycobacterium tuberculosis and Toxoplasma gondii.
Angulo, Jesus, Bidula, Stefan M, Cromer, Brett A, Stokes, Leanne, Walpole, Samuel   +4 more
core   +3 more sources

EGFR signaling-dependent inhibition of glioblastoma growth by ginsenoside Rh2

Tumor Biology, 2014
Glioblastoma is the most common and most aggressive malignant primary brain tumor in humans, accounting for 52 % of all functional tissue brain tumor cases and 20 % of all intracranial tumors. The typical treatment involves a combination of chemotherapy, radiation, and surgery, whereas it still achieves fairly poor patient survival. Ginsenoside Rh2 has
Shaoyi, Li, Yun, Gao, Weining, Ma, Wenchang, Guo, Gang, Zhou, Tianci, Cheng, Yunhui, Liu   +6 more
openaire   +2 more sources

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source

Assessment of a New Ginsenoside Rh2 Nanoniosomal Formulation for Enhanced Antitumor Efficacy on Prostate Cancer: An in vitro Study

Drug Design, Development and Therapy, 2020
Hadi Zare-Zardini,1– 3 Ashraf Alemi,4 Asghar Taheri-Kafrani,5 Seyed Ahmad Hosseini,6 Hossein Soltaninejad,7,8 Amir Ali Hamidieh,9 Mojtaba Haghi Karamallah,10 Majid Farrokhifar,11 Mohammad Farrokhifar12 1Hematology and Oncology Research Center ...
Zare-Zardini H, Alemi A, Taheri-Kafrani A, Hosseini SA, Soltaninejad H, Hamidieh AA, Haghi Karamallah M, Farrokhifar M, Farrokhifar M   +8 more
doaj  

Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]

, 2015
Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu, Oga, Enoche Florence, Sekine, Shuichi, Shitara, Yoshihisa   +3 more
core   +1 more source

Identification of Potential Ebola Virus Nucleoprotein (EBOV NP) Inhibitor Derivate from Various Traditional Medicinal Plants in Indonesia: in silico study [PDF]

, 2021
Ebola virus disease is caused by Ebolavirus infection. Within infection, Ebola nucleoprotein (EBOV NP) is essential part for virus proliferation. Recent report showed that the outbreak was happened in Congo on February 2021.
Antonius, Yulanda, Ongko, Jeremi, Putra, Sulistyo Emantoko Dwi, Sukweenadhi, Johan   +3 more
core   +2 more sources

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source