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GIP’s effect on bone metabolism is reduced by the selective GIP receptor antagonist GIP(3–30)NH2
Bone, 2020Infusion of the incretin hormone glucose-dependent insulinotropic polypeptide (GIP) suppresses the bone resorption marker carboxy-terminal type 1 collagen crosslinks (CTX). Using separate and combined infusions of the selective GIP receptor (GIPR) antagonist, GIP(3-30)NH2, and GIP, we investigated how GIPR inhibition affects bone turnover markers.
Lærke S. Gasbjerg +8 more
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GIP or not GIP? That is the question
Trends in Pharmacological Sciences, 2003Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that is released during a meal and facilitates the disposal of both glucose and fat. Because of the insulinotropic action of GIP, this hormone has been considered as a potential therapy of type 2 diabetes, where insulin secretion is inadequate.
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Physiology of GIP - A Lesson from GIP Receptor Knockout Mice
Hormone and Metabolic Research, 2004A much greater insulin response is observed after oral glucose load than after intravenous injection of glucose. The hormonal factor(s) implicated as transmitters of signals from the gut to pancreatic beta-cells was referred to incretin; gastric inhibitory polypeptide or glucose-dependent insulinotropic polypeptide (GIP) is identified as one of the ...
Y, Yamada, Y, Seino
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GPCR interacting proteins (GIP)
Pharmacology & Therapeutics, 2004G protein-coupled receptors (GPCR) interact not only with heterotrimeric G proteins but also with accessory proteins called GPCR interacting proteins (GIP). These proteins have important functions. They are implicated in GPCR targeting to specific cellular compartments, in their assembling into large functional complexes called "receptosomes," in their
Joël, Bockaert +3 more
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Obesity Surgery, 2010
Bariatric surgery is the most effective modality of achieving weight loss as well as the most effective treatment for type 2 diabetes mellitus (T2DM). Glucose-dependent insulinotropic polypeptide (GIP) is an incretin and is implicated in the pathogenesis of obesity and T2DM. Its role in weight loss and resolution of T2DM after bariatric surgery is very
Raghavendra S, Rao, Subhash, Kini
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Bariatric surgery is the most effective modality of achieving weight loss as well as the most effective treatment for type 2 diabetes mellitus (T2DM). Glucose-dependent insulinotropic polypeptide (GIP) is an incretin and is implicated in the pathogenesis of obesity and T2DM. Its role in weight loss and resolution of T2DM after bariatric surgery is very
Raghavendra S, Rao, Subhash, Kini
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[Gastric inhibitory polypeptide (GIP) and GIP receptor (GIPR)].
Nihon rinsho. Japanese journal of clinical medicine, 1996Gastric inhibitory polypeptide, originally isolated from porcine intestine, is a gastrointestinal hormone belonging to the vasoactive intestinal peptide (VIP)/glucagon/secretin family. GIP consists of 42 amino acid residues which is derived by proteolytic processing of a GIP precursor.
K, Yasuda, Y, Seino
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1998
Die Entwicklung der Bindemittel ist eine vielseitige und an menschlichem Entdecker- und Erfindergeist umfangreiche Geschichte, die von vielen Generationen von Ingenieuren, Baumeistern und Arbeitern gestaltet wurde. Sie ist eng verbunden mit der Verwendung verschiedener Zuschlage wie Sand und/oder Kies unterschiedlicher Zusatze wie Milch ...
Jochen Stark, Bernd Wicht
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Die Entwicklung der Bindemittel ist eine vielseitige und an menschlichem Entdecker- und Erfindergeist umfangreiche Geschichte, die von vielen Generationen von Ingenieuren, Baumeistern und Arbeitern gestaltet wurde. Sie ist eng verbunden mit der Verwendung verschiedener Zuschlage wie Sand und/oder Kies unterschiedlicher Zusatze wie Milch ...
Jochen Stark, Bernd Wicht
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1987
Der Iselin-Verband dient der Ruhigstellung eines Fingers. Wegen seines aufwendigen Aufbaus ist er besonders zur Ruhigstellung von isolierten Frakturen der Mittelhandknochen geeignet. Die exakte anatomische Stellung der Mittelhandfraktur, besonders die Rotation, kann mit diesem Verband kontrolliert werden.
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Der Iselin-Verband dient der Ruhigstellung eines Fingers. Wegen seines aufwendigen Aufbaus ist er besonders zur Ruhigstellung von isolierten Frakturen der Mittelhandknochen geeignet. Die exakte anatomische Stellung der Mittelhandfraktur, besonders die Rotation, kann mit diesem Verband kontrolliert werden.
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