Results 31 to 40 of about 264,589 (263)
Cell Death and Disease, 2021 We determined the antitumor mechanism of apatinib in glioma using a patient-derived orthotopic xenograft (PDOX) glioma mouse model and glioblastoma (GBM) cell lines.
Hui Yao +6 more
doaj +1 more source
Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice [PDF]
, 2015 Mice exposed to standard (SE) or enriched environment (EE) were transplanted with murine or human glioma cells and differences in tumour development were evaluated.
BENIGNI, GIORGIA +13 more
core +1 more source
Establishment of human iPSC-based models for the study and targeting of glioma initiating cells
Nature Communications, 2016 Glioma can originate from the transformation of neural progenitor cells into glioma initiating cells. Here, the authors demonstrate the use of induced pluripotent stem cells as a suitable model for generating neural progenitor cells, which can be ...
Ignacio Sancho-Martinez +22 more
doaj +1 more source
Tumor Microenvironment in Glioma Invasion
Brain Sciences, 2022 A major malignant trait of gliomas is their remarkable infiltration capacity. When glioma develops, the tumor cells have already reached the distant part. Therefore, complete removal of the glioma is impossible.
Sho Tamai +6 more
doaj +1 more source
Essential gene pathways for glioblastoma stem cells: clinical implications for prevention of tumor recurrence. [PDF]
, 2011 Glioblastoma (World Health Organization/WHO grade IV) is the most common and most aggressive adult glial tumor. Patients with glioblastoma, despite being treated with gross total resection and post-operative radiation/chemotherapy, will almost always ...
Choe, Jinny +6 more
core +1 more source
Microglia-derived microvesicles affect microglia phenotype in glioma [PDF]
, 2019 Extracellular-released vesicles (EVs), such as microvesicles (MV) and exosomes (Exo) provide a new type of inter-cellular communication, directly transferring a ready to use box of information, consisting of proteins, lipids and nucleic acids.
Alfonso Grimaldi +14 more
core +5 more sources
Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide. [PDF]
, 2016 Malignant gliomas have poor prognosis and urgently require new therapies. Activating Transcription Factor 5 (ATF5) is highly expressed in gliomas, and interference with its expression/function precipitates targeted glioma cell apoptosis in vitro and in ...
Angelastro, James +11 more
core +2 more sources
Co-culture models for investigating cellular crosstalk in the glioma microenvironment
Cancer Pathogenesis and TherapyGlioma is the most prevalent primary malignant tumor in the central nervous system (CNS). It represents a diverse group of brain malignancies characterized by the presence of various cancer cell types as well as an array of noncancerous cells, which ...
Xiaodong Niu, Yan Zhang, Yuan Wang
doaj +1 more source
Folia Neuropathologica, 2019 We aimed to explore the role of capillary morphogenetic protein 2 (CMG2) in glioma cell invasion and the possible molecular mechanism. Glioma cells U87 and U251 stably overexpressing CMG2 were constructed by lentiviral transfection.
Yifan Xu +5 more
doaj +1 more source
Laser-induced generation of singlet oxygen and its role in the cerebrovascular physiology [PDF]
, 2017 For over 55 years, laser technology has expanded from laboratory research to widespread fields, for example telecommunication and data storage amongst others.
Bragina, O. A. +7 more
core +2 more sources