Evaluation of PLCζ and PAWP Expression in Globozoospermic Individuals
Objective: Globozoospermia is a rare type of teratozoospermia with incidence of 0.1% among infertile individuals. Phospholipase C zeta (PLCζ) and postacrosomal sheath WW domain binding protein (PAWP) are the main candidates in sperm taking ...
Majid Kamali-Dolat Abadi +3 more
doaj
A Comparison of chromatin structure and PLCζ in sperms of subfertile oligoasthenoteratozoospermic and fertile men [PDF]
زمینه و هدف: مهم ترین علل عدم فعال شدن تخمک پس از تکنیک های کمک باروری، عدم رهایش فاکتورهای اسپرمی فعال کننده تخمک و آسیب به DNA اسپرم است. PLCζ یکی از فاکتورهای اسپرمی است که در فعال شدن تخمک نقش دارد.
Ghaedi, Kamran. +4 more
core
Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization.
Squamous cell carcinoma-related oncogene (SCCRO, also known as DCUN1D1) is a component of the E3 for neddylation. As such, DCUN1D1 regulates the neddylation of cullin family members.
Guochang Huang +12 more
doaj +1 more source
Assessment of Sperm DNA Fragmentation in Patients with Partial
Background: Infertility is estimated to affect up to 15% of couples of reproductive age. Globozoospermia is a rare (incidence < 0.1%) but severe disorder in male infertility.
Fereshteh Rasouli +3 more
doaj
The evolving role of genetic tests in reproductive medicine [PDF]
Infertility is considered a major public health issue, and approximately 1 out of 6 people worldwide suffer from infertility during their reproductive lifespans.
Cariati, Federica +2 more
core +1 more source
Overexpression of the protein kinase CK2 increases the survival and resistance to chemotherapy of acute myeloid leukemia cells [PDF]
Background: The critical role of protein kinase CK2 in the regulation of cellular apoptosis suggests its may be involvement in tumor cell resistance to both conventional and unconventional therapies.
PAVAN, LAURA
core +1 more source
Loss of the Na(+)/H(+) exchanger NHE8 causes male infertility in mice by disrupting acrosome formation [PDF]
Mammalian sperm feature a specialized secretory organelle on the anterior part of the sperm nucleus, the acrosome, which is essential for male fertility. It is formed by a fusion of Golgi-derived vesicles.
Jentsch, T.J. +2 more
core +1 more source
Analysis of 232 total fertilization failure cycles during intracytoplasmic sperm injection [PDF]
Background: The intracytoplasmic sperm injection procedure ending with total fertilization failure is very distressfull event for both the clinician and the patient.Objective: The aim of this study was to identify independent factors which could be used ...
Esma Sarikaya +4 more
doaj
Teratozoospermia with cephalic defects is one of the most severe types of sperm defects known to date. While several monogenic factors are linked to cephalic abnormalities, such as globozoospermia and macrozoospermia, the genetic cause of vacuolated ...
Liu Liu +6 more
doaj +1 more source
Comparison of sperm PAWP and chromatin status between normozospermic and ab-normozoospermic men [PDF]
Background and aims: Sperm postacrosomal WW binding protein (PAWP) was expressed during spermiogenesis and recently introduced as one of sperm factors involved in oocyte activation. Therefore, the aim of this study was to compare sperm PAWP and chromatin
Azadi, Leila. +2 more
core

