Results 101 to 110 of about 2,311 (205)

Evaluation of PLCζ and PAWP Expression in Globozoospermic Individuals

open access: yesCell Journal, 2016
Objective: Globozoospermia is a rare type of teratozoospermia with incidence of 0.1% among infertile individuals. Phospholipase C zeta (PLCζ) and postacrosomal sheath WW domain binding protein (PAWP) are the main candidates in sperm taking ...
Majid Kamali-Dolat Abadi   +3 more
doaj  

A Comparison of chromatin structure and PLCζ in sperms of subfertile oligoasthenoteratozoospermic and fertile men [PDF]

open access: yes, 2016
زمینه و هدف: مهم ترین علل عدم فعال شدن تخمک پس از تکنیک های کمک باروری، عدم رهایش فاکتورهای اسپرمی فعال کننده تخمک و آسیب به DNA اسپرم است. PLCζ یکی از فاکتورهای اسپرمی است که در فعال شدن تخمک نقش دارد.
Ghaedi, Kamran.   +4 more
core  

Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization.

open access: yesPLoS ONE, 2019
Squamous cell carcinoma-related oncogene (SCCRO, also known as DCUN1D1) is a component of the E3 for neddylation. As such, DCUN1D1 regulates the neddylation of cullin family members.
Guochang Huang   +12 more
doaj   +1 more source

Assessment of Sperm DNA Fragmentation in Patients with Partial

open access: yesمجله دانشکده پزشکی اصفهان, 2015
Background: Infertility is estimated to affect up to 15% of couples of reproductive age. Globozoospermia is a rare (incidence < 0.1%) but severe disorder in male infertility.
Fereshteh Rasouli   +3 more
doaj  

The evolving role of genetic tests in reproductive medicine [PDF]

open access: yes, 2019
Infertility is considered a major public health issue, and approximately 1 out of 6 people worldwide suffer from infertility during their reproductive lifespans.
Cariati, Federica   +2 more
core   +1 more source

Overexpression of the protein kinase CK2 increases the survival and resistance to chemotherapy of acute myeloid leukemia cells [PDF]

open access: yes, 2013
Background: The critical role of protein kinase CK2 in the regulation of cellular apoptosis suggests its may be involvement in tumor cell resistance to both conventional and unconventional therapies.
PAVAN, LAURA
core   +1 more source

Loss of the Na(+)/H(+) exchanger NHE8 causes male infertility in mice by disrupting acrosome formation [PDF]

open access: yes, 2017
Mammalian sperm feature a specialized secretory organelle on the anterior part of the sperm nucleus, the acrosome, which is essential for male fertility. It is formed by a fusion of Golgi-derived vesicles.
Jentsch, T.J.   +2 more
core   +1 more source

Analysis of 232 total fertilization failure cycles during intracytoplasmic sperm injection [PDF]

open access: yesIranian Journal of Reproductive Medicine, 2011
Background: The intracytoplasmic sperm injection procedure ending with total fertilization failure is very distressfull event for both the clinician and the patient.Objective: The aim of this study was to identify independent factors which could be used ...
Esma Sarikaya   +4 more
doaj  

The identification of AMZ2 as a candidate causative gene in a severe teratozoospermia patient characterized by vacuolated spermatozoa

open access: yesAsian Journal of Andrology
Teratozoospermia with cephalic defects is one of the most severe types of sperm defects known to date. While several monogenic factors are linked to cephalic abnormalities, such as globozoospermia and macrozoospermia, the genetic cause of vacuolated ...
Liu Liu   +6 more
doaj   +1 more source

Comparison of sperm PAWP and chromatin status between normozospermic and ab-normozoospermic men [PDF]

open access: yes, 2018
Background and aims: Sperm postacrosomal WW binding protein (PAWP) was expressed during spermiogenesis and recently introduced as one of sperm factors involved in oocyte activation. Therefore, the aim of this study was to compare sperm PAWP and chromatin
Azadi, Leila.   +2 more
core  

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