Optimization of Heterologous Glucoraphanin Production In Planta [PDF]
ACS Synthetic Biology, 2022 Glucoraphanin is a plant specialized metabolite found in cruciferous vegetables that has long been a target for production in a heterologous host because it can subsequently be hydrolyzed to form the chemopreventive compound sulforaphane before and during consumption.
Collin R. Barnum +4 more
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Analysis of Different Parts of Broccoli (<i>Brassica oleracea</i> var. <i>italica</i>) Leaves and Retention of Functional Compounds Under Different Cooking Methods. [PDF]
Food Sci NutrThis research examines the potential of broccoli leaves, which are often overlooked as a vegetable by‐product, as a functional food ingredient. The study involved phytochemical profiling and an analysis of antioxidant activity across various leaf parts and cooking methods.
Kim MG, Park JH, Joo N.
europepmc +2 more sources
Beneficial Effect of H2S-Releasing Molecules in an In Vitro Model of Sarcopenia: Relevance of Glucoraphanin [PDF]
International Journal of Molecular Sciences, 2022 Sarcopenia is a gradual and generalized skeletal muscle (SKM) syndrome, characterized by the impairment of muscle components and functionality. Hydrogen sulfide (H2S), endogenously formed within the body from the activity of cystathionine-γ-lyase (CSE), cystathionine- β-synthase (CBS), and mercaptopyruvate sulfurtransferase, is involved in SKM function.
Laura Micheli +10 more
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Oral Glucoraphanin and Curcumin Supplements Modulate Key Cytoprotective Enzymes in the Skin of Healthy Human Subjects: A Randomized Trial. [PDF]
MetabolitesChien AL +9 more
europepmc +3 more sources
Effects of nanocarbon solution treatment on the nutrients and glucosinolate metabolism in broccoli
Food Chemistry: X, 2022 The effects of a nanocarbon solution on the nutrients, glucosinolate metabolism and glucoraphanin pathway in broccoli were investigated. Significant positive linear relationships were observed between the nanocarbon solution and total protein yield ...
Zhansheng Li +5 more
doaj +1 more source
Asian Pacific Journal of Cancer Prevention, 2013 Glucoraphanin is the main glucosinolate found in broccoli and other cruciferous vegetables (Brassicaceae). The objective of the study was to evaluate whether glucoraphanin and its breakdown product sulforaphane, are potent modulators of various phase I and phase II enzymes involved in carcinogen-metabolising enzyme systems in vitro.
Ahmad Faizal Abdull Razis +1 more
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Purification of a Sinapine-Glucoraphanin Salt from Broccoli Seeds
American Journal of Plant Sciences, 2010 A sinapine (sinapoylcholine)-glucoraphanin salt has been isolated from broccoli seeds and characterized by NMR and mass spectrometry. This salt extraction method can be used to purify glucoraphanin free from contamination by glucoiberin.
Mark A. Berhow +4 more
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Bioactive Glucosinolate-Rich Extract Promotes Growth in Broccoli Seedlings by Modulating Energy Allocation. [PDF]
Physiol PlantABSTRACT Bioactive extracts derived from plants are emerging as the most innovative and promising alternative to traditional stimulants/chemicals in the agricultural market, given their high availability and rich content of bioactive compounds. Previously, the group synthesized and characterized a Brassicacea extract rich in secondary metabolites such ...
Albaladejo-Marico L +2 more
europepmc +2 more sources
Bioactivated Glucoraphanin Improves Cell Survival, Upregulating Phospho-AKT, and Modulates Genes Involved in DNA Repair in an In Vitro Alzheimer's Disease Model: A Network-Transcriptomic Analysis. [PDF]
NutrientsMinuti A +4 more
europepmc +2 more sources
Applied Sciences, 2023 Broccoli (Brassica oleracea L. var. italica) is a globally popular vegetable because of its nutrient richness, especially its glucosinolates (GSLs). The content of GSLs in different organs of broccoli varies greatly.
Xiuling Tian +7 more
doaj +1 more source