Selenium Biofortification in Radish Enhances Nutritional Quality via Accumulation of Methyl-Selenocysteine and Promotion of Transcripts and Metabolites Related to Glucosinolates, Phenolics, and Amino Acids [PDF]
Two selenium (Se) fertilization methods were tested for their effects on levels of anticarcinogenic selenocompounds in radish (Raphanus sativus), as well as other nutraceuticals.
Annarita Trentin +7 more
core +3 more sources
To investigate the mechanism of melatonin (MT)-mediated glutathione (GSH) in promoting glucoraphanin (GRA) and sulforaphane (SF) synthesis, the gene expression pattern and protein content of hairy broccoli roots under MT treatment were analyzed by a ...
Jinyu Bao +9 more
doaj +1 more source
Protective Activity of Broccoli Sprout Juice in a Human Intestinal Cell Model of Gut Inflammation [PDF]
Benefits to health from a high consumption of fruits and vegetables are well established and have been attributed to bioactive secondary metabolites present in edible plants.
Baima, Simona +14 more
core +3 more sources
Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance [PDF]
Obesity is a low-grade sustained inflammatory state that causes oxidative stress in different metabolic tissues, which leads to insulin resistance and nonalcoholic fatty liver disease (NAFLD). Particularly, obesity-induced metabolic endotoxemia plays an important role in the pathogenesis of insulin resistance and inflammation.
Liang Xu, Naoto Nagata, Tsuguhito Ota
openaire +2 more sources
Glucoraphanin is a plant secondary metabolite that is involved in plant defense and imparts health-promoting properties to cruciferous vegetables. In this study, three genes involved in glucoraphanin metabolism, branched-chain aminotransferase 4 (BCAT4),
Ling Yin +4 more
doaj +1 more source
Bioactive Glucosinolate-Rich Extract Promotes Growth in Broccoli Seedlings by Modulating Energy Allocation. [PDF]
ABSTRACT Bioactive extracts derived from plants are emerging as the most innovative and promising alternative to traditional stimulants/chemicals in the agricultural market, given their high availability and rich content of bioactive compounds. Previously, the group synthesized and characterized a Brassicacea extract rich in secondary metabolites such ...
Albaladejo-Marico L +2 more
europepmc +2 more sources
Transcriptional changes in prostate of men on active surveillance after a 12-mo glucoraphanin-rich broccoli intervention—results from the Effect of Sulforaphane on prostate CAncer PrEvention (ESCAPE) randomized controlled trial [PDF]
Background Epidemiological evidence suggests that consumption of cruciferous vegetables is associated with reduced risk of prostate cancer progression, largely attributed to the biological activity of glucosinolate degradation products, such as ...
Al Kadhi, Omar +18 more
core +1 more source
Novel Gram-Scale Production of Enantiopure R-Sulforaphane from Tuscan Black Kale Seeds
Dietary R-sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. Furthermore, sulforaphane is currently being used in clinical trials to assess its effects against different tumour processes. This study reports an efficient preparation of
Gina Rosalinda De Nicola +3 more
doaj +1 more source
Glucosinolates (GSLs), crucial secondary metabolites in cruciferous vegetables, hydrolyze upon consumption or mechanical damage, forming bioactive compounds with anti-cancer properties, such as glucoraphanin (GRA).
Meijia Yan +8 more
doaj +1 more source
044 Selection for Floret Glucoraphanin Concentration Among Inbred Broccoli [PDF]
Broccoli (Brassica oleracea L. Italica Group) is a rich source of the aliphatic glucosinolate glucoraphanin. The glucoraphanin breakdown product, sulforaphane, has been shown to induce Phase II detoxication enzymes (e.g., Quinone Reductase) and has attracted attention as a potential chemoprotector against cancer. The objectives of this research were to
Mark W. Farnham +2 more
openaire +1 more source

