Results 61 to 70 of about 8,445 (200)
Glyoxalase II promotes "in vitro" S-glutathionylation.
, 2014 S-glutathionylation involves the reversible formation of a mix disulphide-bridge between specific cysteine and a molecule of glutathione, the major non-protein antioxidant compound in the cell.
M. +7 more
core +1 more source
Antioxidants, 2023 Pathogenic helminths have evolved mechanisms to preserve reproductive function while surviving long-term in the host via robust protective responses.
Jeong-Geun Kim +4 more
doaj +1 more source
New Phytologist, EarlyView.Conservation of post‐translational modifications (PTMs) in histones across six plant species.
Sau‐Shan Cheng +3 more
wiley +1 more source
Antioxidants, 2020 Dicarbonyl stress is a dysfunctional state consisting in the abnormal accumulation of reactive α-oxaldehydes leading to increased protein modification.
Cinzia Antognelli +4 more
doaj +1 more source
Sirtuin Oxidative Post-translational Modifications
Frontiers in Physiology, 2021 Increased sirtuin deacylase activity is correlated with increased lifespan and healthspan in eukaryotes. Conversely, decreased sirtuin deacylase activity is correlated with increased susceptibility to aging-related diseases.
Kelsey S. Kalous +2 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Glutathionylation of beta-actin via a cysteinyl sulfenic acid intermediary
, 2007 BACKGROUND: Cysteinyl residues in actin are glutathionylated, ie. form a mixed disulfide with glutathione, even in the absence of exogenous oxidative stress.
Lundberg, M,, Johansson, M
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray +16 more
wiley +1 more source
The busulfan metabolite EdAG irreversibly glutathionylates glutaredoxins [PDF]
Archives of Biochemistry and Biophysics, 2015 The DNA alkylating agent busulfan is used to 'precondition' patients with leukemia, lymphomas and other hematological disorders prior to hematopoietic stem cell transplants. Busulfan is metabolized via conjugation with glutathione (GSH) followed by intramolecular rearrangement to the GSH analog γ-glutamyl-dehydroalanyl -glycine (EdAG).
Michele, Scian, William M, Atkins
openaire +2 more sources
Reversible and Irreversible Protein Glutathionylation: Biological and Clinical Aspects
, 2011 INTRODUCTION: Depending in part on the glutathione:glutathione disulfide ratio, reversible protein glutathionylation to a mixed disulfide may occur.
Patrick S Callery +5 more
core +1 more source