Results 51 to 60 of about 19,474 (199)
Amadori albumin in diabetic nephropathy
Nonenzymatic glycation of macromolecules in diabetes mellitus (DM) is accelerated due to persistent hyperglycemia. Reducing sugar such as glucose reacts non enzymatically with free €- amino groups of proteins through series of reactions forming Schiff ...
Km. Neelofar, Jamal Ahmad
doaj +1 more source
Human serum albumin (HSA) has an important antioxidant activity due to the presence of the reduced cysteine at position 34, which represents the most abundant free thiol in the plasma.
Francesco Piarulli +7 more
doaj +1 more source
Naloxone inhibits human serum albumin Glycation
Advanced glycation end-products (AGEs) are formed by non-enzymatic reaction between reducing sugar and protein. AGEs play important roles in pathogenesis of diabetic, aging complications, endothelial dysfunction and neurological diseases such as the Alzheimer’s disease.
Ahmadzadeh, Alireza +3 more
openaire +1 more source
Postmortem diagnosis of diabetes mellitus and its complications. [PDF]
Diabetes mellitus has become a major cause of death worldwide and diabetic ketoacidosis is the most common cause of death in children and adolescents with type 1 diabetes.
Palmiere, C.
core +3 more sources
Advanced glycation endproducts in the pathogenesis of chronic kidney disease [PDF]
Advanced glycation endproducts (AGEs) are stable post-translational modifications of proteins formed by the spontaneous reaction with glucose and related metabolites. Important AGEs quantitatively are methylglyoxal (MG)-derived hydroimidazolone MG-H1, Nε-
Rabbani, Naila, Thornalley, Paul J.
core +1 more source
Streptozotocin induced hyperglycemia in the axolotl
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen +2 more
wiley +1 more source
A simple, sensitive, fast, and economical HPLC method was developed and validated for simultaneous estimation of two fixed dose combinations frequently prescribed in diabetes (Metformin plus Glibenclamide) and hypertension with dyslipidemia (Amlodipine ...
Pawan K. Porwal, Gokul S. Talele
doaj +1 more source
Deciphering metal-induced oxidative damages on glycated albumin structure and function [PDF]
Background: Metal ions such as copper or zinc are involved in the development of neurodegenerative pathologies and metabolic diseases such as diabetes mellitus.
Baraka Vidot, J +5 more
core +1 more source
Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger +15 more
wiley +1 more source
Fibroblast viability and phenotypic changes within glycated stiffened three-dimensional collagen matrices [PDF]
Background: There is growing interest in the development of cell culture assays that enable the rigidity of the extracellular matrix to be increased. A promising approach is based on three-dimensional collagen type I matrices that are stiffened by cross ...
Alcaraz Casademunt, Jordi +12 more
core +1 more source

