Results 51 to 60 of about 19,474 (199)

Amadori albumin in diabetic nephropathy

open access: yesIndian Journal of Endocrinology and Metabolism, 2015
Nonenzymatic glycation of macromolecules in diabetes mellitus (DM) is accelerated due to persistent hyperglycemia. Reducing sugar such as glucose reacts non enzymatically with free €- amino groups of proteins through series of reactions forming Schiff ...
Km. Neelofar, Jamal Ahmad
doaj   +1 more source

The Burden of Impaired Serum Albumin Antioxidant Properties and Glyco-Oxidation in Coronary Heart Disease Patients with and without Type 2 Diabetes Mellitus

open access: yesAntioxidants, 2022
Human serum albumin (HSA) has an important antioxidant activity due to the presence of the reduced cysteine at position 34, which represents the most abundant free thiol in the plasma.
Francesco Piarulli   +7 more
doaj   +1 more source

Naloxone inhibits human serum albumin Glycation

open access: yesArchives of Advances in Biosciences, 2014
    Advanced glycation end-products (AGEs) are formed by non-enzymatic reaction between reducing sugar and protein. AGEs play important roles in pathogenesis of diabetic, aging complications, endothelial dysfunction and neurological diseases such as the Alzheimer’s disease.
Ahmadzadeh, Alireza   +3 more
openaire   +1 more source

Postmortem diagnosis of diabetes mellitus and its complications. [PDF]

open access: yes, 2015
Diabetes mellitus has become a major cause of death worldwide and diabetic ketoacidosis is the most common cause of death in children and adolescents with type 1 diabetes.
Palmiere, C.
core   +3 more sources

Advanced glycation endproducts in the pathogenesis of chronic kidney disease [PDF]

open access: yes, 2018
Advanced glycation endproducts (AGEs) are stable post-translational modifications of proteins formed by the spontaneous reaction with glucose and related metabolites. Important AGEs quantitatively are methylglyoxal (MG)-derived hydroimidazolone MG-H1, Nε-
Rabbani, Naila, Thornalley, Paul J.
core   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen   +2 more
wiley   +1 more source

Development of validated HPLC-UV method for simultaneous determination of Metformin, Amlodipine, Glibenclamide and Atorvastatin in human plasma and application to protein binding studies

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2017
A simple, sensitive, fast, and economical HPLC method was developed and validated for simultaneous estimation of two fixed dose combinations frequently prescribed in diabetes (Metformin plus Glibenclamide) and hypertension with dyslipidemia (Amlodipine ...
Pawan K. Porwal, Gokul S. Talele
doaj   +1 more source

Deciphering metal-induced oxidative damages on glycated albumin structure and function [PDF]

open access: yes, 2014
Background: Metal ions such as copper or zinc are involved in the development of neurodegenerative pathologies and metabolic diseases such as diabetes mellitus.
Baraka Vidot, J   +5 more
core   +1 more source

Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.
Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger   +15 more
wiley   +1 more source

Fibroblast viability and phenotypic changes within glycated stiffened three-dimensional collagen matrices [PDF]

open access: yes, 2015
Background: There is growing interest in the development of cell culture assays that enable the rigidity of the extracellular matrix to be increased. A promising approach is based on three-dimensional collagen type I matrices that are stiffened by cross ...
Alcaraz Casademunt, Jordi   +12 more
core   +1 more source

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