Study of Serum Betatrophin Level as a Biochemical Marker in Patients with Type-2 Diabetes Mellitus [PDF]
International Journal of Medical Arts, 2022 Background: Type 2diabetes mellitus [T2DM] is a global health problem with high morbidity and mortality. Betatrophin is a novel circulating protein produced by the adipose tissue and the liver.
Mona Elghaba +3 more
doaj +1 more source
Prevention of Protein Glycation by Natural Compounds [PDF]
, 2015 Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz +1 more
core +2 more sources
Oxidative stress, protein glycation and nutrition – interactions relevant to health and disease throughout the lifecycle [PDF]
, 2014 Protein glycation has been studied for over a century now and plays an important role in disease pathogenesis throughout the lifecycle. Strongly related to diabetic complications, glycation of Hb has become the gold standard method for diabetes diagnosis
American Diabetes +17 more
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DJ-1 as a deglycating enzyme: A unique function to explain a multifaceted protein? [PDF]
, 2017 The recently reported deglycating activity of DJ-1 reconciles several features previously described for the protein. The deglycating activity reported for DJ-1 may explain its different subcellular localizations, indeed the protein has been found in the ...
Bisaglia, Marco, DE LAZZARI, Federica
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Annals of Hepatology, 2023 Introduction and Objectives: Non-oncotic albumin functions such as transport, antioxidant and immunomodulatory capacities may be associated with the beneficial effects of albumin therapy in liver disease patients. For acute-on-chronic liver failure (ACLF)
Raquel Horrillo +9 more
doaj +1 more source
Influence of biological variations and sample handling on measured microalbuminuria in diabetic patients [PDF]
, 1992 Five immunochemical assays for determining low concentrations of albumin were investigated. These were a radioimmunoassay (RIA); turbidimetric immunoassays (TIA) both according to end-point measuring principle on a Cobas Fara and Hitachi 717 analysers ...
Cowell +19 more
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Garlic Extract: Inhibition of Biochemical and Biophysical Changes in Glycated HSA
Applied Sciences, 2021 Glycation of various biomolecules contributes to structural changes and formation of several high molecular weight fluorescent and non-fluorescent, advanced glycation end products (AGEs).
Mohd W. A. Khan +8 more
doaj +1 more source
Different behaviour of the N-terminal and C-terminal fragment of proatrial natriuretic factor in plasma of healthy subjects as well as of patients with cirrhosis [PDF]
, 1990 N-terminal (atrial natriuretic factor (ANF) 1-98) and C-terminal (ANF 99-126) fragments of proatrial natriuretic factor (NTA and CTA, respectively) were determined in plasma of healthy subjects adopting different postures and in patients with cirrhosis ...
Arendt, Rainer M. +5 more
core +1 more source
Pharmacologic approaches against advanced glycation end products (ages) in diabetic cardiovascular disease [PDF]
, 2015 Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients.
Avtaar Singh, Sanjeet Singh +6 more
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The effects of glycation on the binding of human serum albumin to warfarin and l-tryptophan [PDF]
Journal of Pharmaceutical and Biomedical Analysis, 2010 Diabetes leads to elevated levels of glucose in blood which, in turn, can lead to the non-enzymatic glycation of serum proteins such as human serum albumin (HSA). It has been suggested that this increase in glycation can alter the ability of HSA to bind to drugs and other small solutes. This study used high-performance affinity chromatography (HPAC) to
Joseph, K.S., Hage, David S.
openaire +2 more sources