Glycated and Non-Glycated Human Alpha-1 Antitrypsin in Hyperglycemic Wound Healing: In Vivo and In Vitro Models [PDF]
BiologyImpaired wound healing is a major cause of morbidity among patients with diabetes. Human α1-antitrypsin (hAAT) promotes the resolution of injured tissues.
Idan Farber +12 more
doaj +2 more sources
Simultaneous electrochemical detection of glycated and human serum albumin for diabetes management
Biosensors and BioelectronicsDeveloping highly selective and sensitive biosensors for diabetes management blood glucose monitoring is essential to reduce the health risks associated with diabetes. Assessing the glycation (GA) of human serum albumin (HSA) serves as an indicator for medium-term glycemic control, making it suitable for assessing the efficacy of blood glucose ...
Monalisha Ghosh Dastidar +2 more
exaly +3 more sources
Biophysical Characterisation of Amadori Modified Human Serum Albumin: A Prognostic Biomarker for Diabetic Complications [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Glycation of biological macromolecules particularly protein leads to the generation of early and Advanced Glycation End (AGE) products. The interest in early glycation of protein is driven due to the fact of Amadori modified proteins having
Binish Arif +4 more
doaj +1 more source
Association between serum neutrophil extracellular traps and carotid intima-media thickness in type 2 diabetes: a cross-sectional study [PDF]
Frontiers in EndocrinologyBackgroundAtherosclerosis is a chronic low-grade inflammatory vascular disease and serves as the core pathological basis for cardiovascular complications in patients with type 2 diabetes mellitus (T2DM).
Xinyan Jin +4 more
doaj +2 more sources
Tuning Human Serum Albumin (HSA) Hydrogels through Albumin Glycation
Macromolecular Bioscience, 2023 AbstractThe changes of technological properties of albumin‐based hydrogels induced by increasing degrees of post‐translational modification of the protein are reported. Maillard‐type modification of amino acids arginine and lysine of albumin is achieved through glyoxal as an α‐dicarbonyl compound.
Jonas Volmer +4 more
openaire +4 more sources
Biosensors, 2021 An immobilization-free electrochemical sensor coupled with a graphene oxide (GO)-based aptasensor was developed for glycated human serum albumin (GHSA) detection.
Wassa Waiwinya +5 more
doaj +1 more source
Proteolytic Sensitivity, In Vitro Glycation Efficiency of Diabetic and Non-diabetic Human Serum Albumin [PDF]
Avicenna Journal of Medical Biochemistry, 2022 Background: Glycation of human serum albumin (HSA) leads to disturbances in its stability, activity, and other properties which, in turn, affect the functional properties of HSA.
Hadiya Husain, Riaz Ahmad
doaj +1 more source
Frontiers in Physiology, 2021 The role of inflammation in airway epithelial cells and its regulation are important in several respiratory diseases. When disease is present, the barrier between the pulmonary circulation and the airway epithelium is damaged, allowing serum proteins to ...
Moira L. Aitken +8 more
doaj +1 more source
Comprehensive overview of human serum albumin glycation in diabetes mellitus
World Journal of Diabetes, 2021 The presence of excess glucose in blood is regarded as a sweet hurt for patients with diabetes. Human serum albumin (HSA) is the most abundant protein in human plasma, which undergoes severe non-enzymatic glycation with glucose in patients with diabetes; this modifies the structure and function of HSA.
Qiu, Hong-Yan +6 more
openaire +2 more sources
Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction [PDF]
, 2017 Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has ...
Andreozzi F +6 more
core +3 more sources