Results 11 to 20 of about 6,575 (136)
Endothelial glycocalyx conditions influence nanoparticle uptake for passive targeting
International Journal of Nanomedicine, 2016 Ming J Cheng,1 Rajiv Kumar,2 Srinivas Sridhar,1–3 Thomas J Webster,1,4 Eno E Ebong1 1Department of Chemical Engineering, 2Department of Physics, Northeastern University, 3Department of Radiation Oncology, Harvard Medical School, Boston, MA, USA ...
Cheng MJ +4 more
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The role of endothelial glycocalyx in sepsis [PDF]
Bali Journal of Anesthesiology, 2019 The surface of endothelial cells is filled with various membrane-bound molecules that form the glycocalyx. The endothelial glycocalyx is a surface layer mainly consisted of glycosaminoglycans that include heparan sulfate, chondroitin sulfate, and ...
I Nyoman Budi Hartawan, Made Wiryana
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The glycocalyx affects the mechanotransductive perception of the topographical microenvironment [PDF]
Journal of Nanobiotechnology, 2022 The cell/microenvironment interface is the starting point of integrin-mediated mechanotransduction, but many details of mechanotransductive signal integration remain elusive due to the complexity of the involved (extra)cellular structures, such as the ...
Matteo Chighizola +13 more
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Absence of the Epithelial Glycocalyx As Potential Tumor Marker for the Early Detection of Colorectal Cancer. [PDF]
PLoS ONE, 2016 Detection of cancer at an early stage is pivotal for successful treatment and long term survival, yet early diagnosis requires sensitive and specific markers that can be easily detected by screening procedures.
Katrin Ramaker +7 more
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Near wall hemodynamics: Modelling the glycocalyx and the endothelial surface [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Spencer, TJ +6 more
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Fluid shear stress-dependent modulation of the basal endothelial glycocalyx.
PLoS ONEThe vascular endothelial glycocalyx is a major regulator of endothelium function, serving as a vital mechanotransducer and barrier. Shear stress due to blood flow exerted on the apical endothelial cell (EC) and glycocalyx have been the primary focus of ...
Zoe Vittum, Solomon A Mensah
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Studying the Endothelial Glycocalyx in vitro: What Is Missing? [PDF]
, 2021 All human cells are coated by a surface layer of proteoglycans, glycosaminoglycans (GAGs) and plasma proteins, called the glycocalyx. The glycocalyx transmits shear stress to the cytoskeleton of endothelial cells, maintains a selective permeability ...
Emily S Wood (16285316) +29 more
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Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx [PDF]
, 2008 A healthy vascular endothelium is coated by the endothelial glycocalyx. Its main constituents are transmembrane syndecans and bound heparan sulphates. This structure maintains the physiological endothelial permeability barrier and prevents leukocyte and ...
Rehm, Markus +6 more
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Mediators of Inflammation, 2023 This review aims at summarizing state-of-the-art knowledge on glycocalyx and SARS-CoV-2. The endothelial glycocalyx is a dynamic grid overlying the surface of the endothelial cell (EC) lumen and consists of membrane-bound proteoglycans and glycoproteins.
Bingxuan Lv +4 more
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Resuscitation fluids as drugs: targeting the endothelial glycocalyx
Chinese Medical Journal, 2022 . Fluid resuscitation is an essential intervention in critically ill patients, and its ultimate goal is to restore tissue perfusion. Critical illnesses are often accompanied by glycocalyx degradation caused by inflammatory reactions, hypoperfusion, shock,
Guangjian Wang +5 more
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