Results 231 to 240 of about 88,369 (330)

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

Pediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie, Qian Zhou, Jianxiang Liao, Yuejie Zheng, Wenjian Wang, Kunling Shen   +5 more
wiley   +1 more source

Imaging hallmarks of mucopolysaccharidosis in a young Ethiopian boy: A case report. [PDF]

Radiol Case Rep
Gebresilassie MY, Mehammed AH, Damtie MY, Midekso HD, Bezabih NA, Abera MT, Worku AB.   +6 more
europepmc   +1 more source

In Silico Structural Analysis of Human β‐Glucuronidase for Antibody–Drug Conjugates Optimization

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Human β‐glucuronidase (HGUSB), a key lysosomal glycosyl hydrolase for the degradation pathway of glycosaminoglycans (GAGs), plays a crucial role in cell proliferation and inflammation, making it a promising target for novel therapeutic strategies including antibody‐drug conjugates (ADCs) with β‐glucuronic linkers.
Giorgia Canini, Simona Saporiti, Crescenzo Coppa, Mara Rossi, Fabio Centola, Alessandro Arcovito   +5 more
wiley   +1 more source

Is there a role of radiotherapy for steroid-resistant thyroid eye disease? [PDF]

Radiat Oncol J
Noh JM.
europepmc   +1 more source

Injectable Biomimetic Composite Hydrogel Scaffold With Tissue‐Engineered Cartilage Matrix for Articular Cartilage Regeneration

Rare Metals, EarlyView.
ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu, Jun‐Jie Jiang, Hang Yao, Xian‐Feng Shang, Ming‐Di Zheng, Xu Hu, Shuo Xu, Jun‐Li Shi, Yan Han, Chi‐Run Wang, Qi Tao, Huai‐Guo Xue, Dong‐An Wang, Yu‐Chi Zhao   +13 more
wiley   +1 more source

Sulfated Hyaluronan in Dermatology: What's New? Overview of Evidence in Specific Dermatological Diseases. [PDF]

Pharmaceutics
Pellacani G, Michelini S, Trovato F, Rallo A, Gemma G, Chello C, Pavan M, Guarise C, Passi AG.   +8 more
europepmc   +1 more source

Histochemical Study of Glycosaminoglycan in Wilms Tumors of Rats and Rabbits and Fetal Kidneys of Rats

, 1982
Masaaki Okada, Yoshikazu Suzuki, Tanetaka Chiba, Mitsuko Sobue, Jun Takeuchi   +4 more
openalex   +2 more sources

Scale‐Specific Viscoelastic Characterization of Hydrogels: Integrated AFM and Finite Element Modeling

Small, EarlyView.
An integrated multiscale approach reveals distinct viscoelastic responses of hydrogels across length scales. Combining AFM‐based nanoindentation, finite element modeling, and a novel analytical framework, this study enables accurate, scale‐specific mechanical characterization to guide the design of advanced biomaterials. Abstract Viscoelastic hydrogels
Nicole Fertala, Klemens Uhlmann, Evgeny Grigoryev, Prannoy Seth, Jens Friedrichs, Julian Thiele, Carsten Werner, Daniel Balzani   +7 more
wiley   +1 more source

Glycosaminoglycans as Polyelectrolytes: Charge, Interactions, and Applications. [PDF]

Chembiochem
Szekeres GP, Moon E, Elter JK, Roper B, Kizhakkedathu JNN, Ballauff M, Haag R, Pagel K.   +7 more
europepmc   +1 more source

Competitive Inhibition of Heparinase by Persulfonated Glycosaminoglycans: A Tool to Detect Heparin Contamination

, 2011
Udayanath Aich, Zachary Shriver, Kannan Tharakaraman, Rahul Raman, Ram Sasisekharan   +4 more
openalex   +2 more sources