Results 61 to 70 of about 10,037 (210)

Structural Enzymology of Cellvibrio japonicus Agd31B Protein Reveals α-Transglucosylase Activity in Glycoside Hydrolase Family 31 [PDF]

, 2012
The metabolism of the storage polysaccharides glycogen and starch is of vital importance to organisms from all domains of life. In bacteria, utilization of these -glucans requires the concerted action of a variety of enzymes, including glycoside ...
Adams, Atsushi Izumi, Ball, Barends, Becker, Berezina, Boos, Burlingham, Cantarel, Cowtan, Davies, Davies, DeBoy, Dippel, Elbein, Emsley, Ernst, Gasteiger, Gibson, Gideon J. Davies, Glyn R. Hemsworth, Harry Brumer, Hazlewood, Hendlich, Humphry, Janecek, Johan Larsbrink, Jones, Jung, Kato, Kim, Kim, Kim, Larsbrink, Lee, Lee, Leemhuis, Leslie, Liebl, Lovering, Meissner, Mukai, Okuyama, Palmer, Perrakis, Przylas, Ren, Roach, Rossi, Roujeinikova, Roujeinikova, Schwartz, Seo, Sim, Sim, Sinnott, Stam, Stick, Sundqvist, Suzuki, Takaha, Takaha, Tan, Terada, Vagin, Vonrhein, Wang, Wilson, Winn, Withers, Yamamoto, Zhou   +71 more
core   +1 more source

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source

Spiro-epoxyglycosides as Activity-Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase [PDF]

, 2018
N-Glycans direct protein function, stability, folding and targeting, and influence immunogenicity. While most glycosidases that process N-glycans cleave a single sugar residue at a time, enzymes from glycoside hydrolase family 99 are endo-acting enzymes ...
Akasaka-Manya, Corey, Cravatt, Crich, Cuskin, Despras, Feizi, Foddy, Fujimoto, Garman, Gebler, Hakki, Havukainen, Helenius, Herscovics, Heuckendorff, Iwamoto, Jiang, Kaczmarek, Kallemeijn, Koshland, Ladmiral, Legler, Lombard, Lubas, Lubas, Martín-Lomas, Molinari, Moore, Motawia, Nakajima, Pan, Pedersen, Petricevic, Sasak, Sato, Sohn, Spiro, Thompson, van der Vorm, Van der Vorm, Vogel, Völker, Willems, Witte, Zhang, Zhao   +46 more
core   +3 more sources

The role of the gut microbiome in the regulation of high‐altitude adaptation

iMeta, EarlyView.
This study is the first to elucidate mechanisms of high‐altitude adaptation from the perspective of the rumen ecosystem by using indigenous yaks and Holstein cows that have lived at high altitude since birth as comparative models. Through a systematic comparison of their rumen ecology using multi‐omics approaches—including rumen metagenomics ...
Xinyu Zhang, Senlin Zhu, Michael Kreuzer, Shoukun Ji, Wei Wang, Yanliang Bi, Shengli Li   +6 more
wiley   +1 more source

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut [PDF]

, 2016
The human gastrointestinal tract harbours myriad bacterial species, collectively termed the microbiota, that strongly influence human health. Symbiotic members of our microbiota play a pivotal role in the digestion of complex carbohydrates that are ...
Brumer, Harry, Coyle, Travis, Davies, Gideon J., Goddard-Borger, Ethan D., Hemsworth, Glyn R., Larsbrink, Johan, Sobala, Łukasz F., Spadiut, Oliver, Stepper, Judith, Stubbs, Keith A., Thompson, Andrew J.   +10 more
core   +3 more sources

A DUF3455 domain‐containing protein promotes Ustilaginoidea virens infection and functions as a plant immune elicitor

New Plant Protection, EarlyView.
The fungal effector UvDUF1 from Ustilaginoidea virens not only promotes infection but also acts as a plant immunity elicitor, inducing broad‐spectrum disease resistance in rice and Nicotiana benthamiana. These results reveal its potential as a novel target for sustainable crop protection strategies.
Shuchen Wang, Wen Zhang, Wenyue Zheng, Qian Zhang, Mina Yu, Junjie Yu, Huijuan Cao, Xiayan Pan, Zhongqiang Qi, Yan Du, Rongsheng Zhang, Yunpeng Wang, Yongfeng Liu, Tianqiao Song   +13 more
wiley   +1 more source

Antagonistic functions of CTL1 and SUH1 mediate cell wall assembly in Arabidopsis

Plant Direct
Plant genomes contain numerous genes encoding chitinase‐like (CTL) proteins, which have a similar protein structure to chitinase belonging to the glycoside hydrolase (GH) family but lack the chitinolytic activity to cleave the β‐1,4‐glycosidic bond in ...
Nguyen Thi Thuy, Hyun‐Jung Kim, Suk‐Whan Hong   +2 more
doaj   +1 more source

Lytic polysaccharide monooxygenases and other oxidative enzymes are abundantly secreted by Aspergillus nidulans grown on different starches [PDF]

, 2016
Additional file 5: Tables S3–S5. Table S3. Top 20 detected proteins in the secretome of Aspergillus nidulans during growth on wheat starch at day 3, 4 and 5. Table S4.
Birte Svensson, Gustav Vaaje-Kolstad, Laura Nekiunaite, Magnus Ø. Arntzen, Maher Abou Hachem   +4 more
core   +7 more sources

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Docking studies on glycoside hydrolase Family 47 endoplasmic reticulum α-(1→2)-mannosidase I to elucidate the pathway to the substrate transition state [PDF]

, 2012
α-(1→2)-Mannosidase I from the endoplasmic reticulum (ERManI), a Family 47 glycoside hydrolase, is a key enzyme in the N-glycan synthesis pathway. Catalytic-domain crystal structures of yeast and human ERMan1s have been determined, the former with a ...
Mulakala, Chandrika, Nerinckx, Wim, Reilly, Peter, Reilly, Peter   +3 more
core   +2 more sources