Results 121 to 130 of about 36,633 (265)

Dihydromyricetin Regulates PANoptosis to Protect Salmonella Typhimurium‐Infected Weaned Piglets

Food Frontiers, Volume 7, Issue 2, March 2026.
After DHM pretreatment, piglets were subjected to Salmonella infection. Serum and ileocecal samples from the piglets were collected for TUNEL assay, Western blotting analysis, and metabolomics analysis. The results collectively indicated that DHM could protect piglets from Salmonella infection.
Tingting Xiao, Xinyi Tian, YiKun Li, Jie Zhang, Hongcan Huang, Yu‐Xuan Lyu, Baichuan Deng   +6 more
wiley   +1 more source

Structural Insights into Escherichia coli Shiga Toxin (Stx) Glycosphingolipid Receptors of Porcine Renal Epithelial Cells and Inhibition of Stx-Mediated Cellular Injury Using Neoglycolipid-Spiked Glycovesicles

Microorganisms, 2019
Shiga toxin (Stx) producing Escherichia coli (STEC) cause the edema disease in pigs by releasing the swine-pathogenic Stx2e subtype as the key virulence factor.
Johanna Detzner, Caroline Gloerfeld, Gottfried Pohlentz, Nadine Legros, Hans-Ulrich Humpf, Alexander Mellmann, Helge Karch, Johannes Müthing   +7 more
doaj   +1 more source

Upcycling Agricultural By‐Product: Therapeutic Potential of Oriental Melon Stem (Cucumis melo var. makuwa) in Treating Obesity and Fatty Liver via Enhanced Thermogenesis

Food Frontiers, Volume 7, Issue 2, March 2026.
This study proposes the upcycling of oriental melon (Cucumis melo var. makuwa) stems, typically discarded as agricultural waste, into a bioactive extract with functional potential. CMSE ameliorates high‐fat‐diet‐induced obesity and fatty liver, contributing to the restoration of metabolic health by enhancing the expression of thermogenesis‐related ...
Myeong‐Jin Kim, Ji Yun Van, Su‐Yeon Park, Ji Young Hwang, Yerin Seong, Yeo Jin Park, Seokmin Lee, Bo‐mi Ryu, Joo Yun Jun, Won‐Kyo Jung, Bonggi Lee   +10 more
wiley   +1 more source

Biosynthesis and metabolic degradation of sphingolipids not containing sialic acid

Journal of Lipid Research, 1972
Interest in sphingolipid metabolism has increased rapidly during the past decade, and many of the steps involved in the biosynthesis and metabolic degradation of sphingolipids are now known. In this review these studies are critically exmined.
Pierre Morell, Peter Braun
doaj   +1 more source

Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease [PDF]

, 2016
Niemann-Pick type C disease is an autosomal recessive storage disorder, characterized by abnormal sequestration of unesterified cholesterol within the late endolysosomal compartment of cells and accumulation of gangliosides and other sphingolipids ...
Cardinale, A, Cutarelli, A, D'Arcangelo, G, Frank, C, Grossi, D, Merlo, D, Racaniello, M, Rufini, S, Tancredi, V, Zaratti, A   +9 more
core   +4 more sources

Iminosugar-Based Inhibitors of Glucosylceramide Synthase Increase Brain Glycosphingolipids and Survival in a Mouse Model of Sandhoff Disease

PLoS ONE, 2011
The neuropathic glycosphingolipidoses are a subgroup of lysosomal storage disorders for which there are no effective therapies. A potential approach is substrate reduction therapy using inhibitors of glucosylceramide synthase (GCS) to decrease the ...
K. Ashe, D. Bangari, Lingyun Li, M. Cabrera-Salazar, S. Bercury, J. Nietupski, Christopher G. F. Cooper, J. Aerts, Edward R. Lee, D. Copeland, Seng H. Cheng, R. Scheule, J. Marshall   +12 more
semanticscholar   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, Volume 12, Issue 1, Page 96-122, Spring 2026.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source

The Faculty Notebook, April 2018

, 2018
The Faculty Notebook is published periodically by the Office of the Provost at Gettysburg College to bring to the attention of the campus community accomplishments and activities of academic interest.
Provost\u27s Office,
core   +1 more source

Contribution of Host Genetics and Maternal Inflammatory Bowel Disease to Fecal Calprotectin and Microbiota Composition During Early Life

JCC Plus, Volume 1, Issue 2, March 2026.
ABSTRACT Background and Aims Parental diagnosis is one of the strongest predictors of developing inflammatory bowel disease (IBD) in offspring. However, the contribution of genetic heritability versus exposure to the perinatal environment remains poorly understood.
Paola Nicoletti, Won Jun Lee, Adam Cantor, Leonid Tarassishin, Samreen Zafer, Jianzhong Hu, Mellissa Picker, Alexa Rendon, Anketse Debebe, Isabella Nguyen, Joanne Stone, Manasi Agrawal, Jean‐Frederic Colombel, Joana Torres, Jose C. Clemente, Inga Peter   +15 more
wiley   +1 more source

Quantification and a Molecular Dynamics Study of Viral Membrane Lipids through Plasmon Coupling Microscopy [PDF]

, 2015
Phosphatidylserine (PS) and monosialotetrahexosylganglioside (G_M1) are examples of two host-derived lipids in the membrane of enveloped virus particles that are known to contribute to virus attachment, uptake, and ultimately dissemination.
Feizpour, Amin, Reinhard, Björn
core   +1 more source