Results 11 to 20 of about 25,840 (267)

Lipidomics of Glycosphingolipids [PDF]

open access: yesMetabolites, 2012
Glycosphingolipids (GSLs) contain one or more sugars that are attached to a sphingolipid moiety, usually to a ceramide, but in rare cases also to a sphingoid base.
Hany Farwanah, Thomas Kolter
doaj   +4 more sources

Glycosphingolipids in human parasites

open access: yesFEBS Open Bio, 2023
Glycosphingolipids (GSLs) are comprised of glycans (oligosaccharides) linked to a lipid containing a sphingosine moiety. They are major membrane components in cells of most animals, and importantly, they also occur in parasitic protozoans and worms that ...
Richard D. Cummings
doaj   +3 more sources

Glycosphingolipids from cultured astroblasts

open access: yesJournal of Lipid Research, 1977
The glycolipids of two clonal lines astroblasts, NN clone and C6 clone, were studied. Glucosylceramide and lactosylceramide were present at very low levels in both clones, but the most common myelin glycolipids galactosylceramide and sulfatide, were not ...
J Robert, G Rebel, P Mandel
doaj   +3 more sources

Characterization of moose intestinal glycosphingolipids [PDF]

open access: yesGlycoconjugate Journal, 2015
As a part of a systematic investigation of the species-specific expression of glycosphingolipids, acid and non-acid glycosphingolipids were isolated from three small intestines and one large intestine of the moose (Alces alces).
Miralda Madar Johansson   +6 more
semanticscholar   +3 more sources

Chemoenzymatically Synthesized O-Acetylated GD3 Gangliosides to Examine Viral Receptor Specificities in a Cellular Context. [PDF]

open access: yesAngew Chem Int Ed Engl
7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhang Z   +5 more
europepmc   +3 more sources

Review and Proposal of Alternative Technologies for Comprehensive and Reliable Newborn Screening Using Paper Borne Urine Samples for Lysosomal Storage Disorders: Glycosphingolipid Disorders

open access: yesJournal of Inborn Errors of Metabolism and Screening, 2021
Few current methods are efficient to detect a high number of lysosomal storage disorders (LSDs) in newborn screening. Therefore, we propose a stepwise procedure that starts with the use of paper borne urine samples (Berry-Woolf specimen) for the ...
José Ramón Alonso-Fernández   +1 more
doaj   +1 more source

Metabolism of Glycosphingolipids and Their Role in the Pathophysiology of Lysosomal Storage Disorders

open access: yesInternational Journal of Molecular Sciences, 2020
Glycosphingolipids (GSLs) are a specialized class of membrane lipids composed of a ceramide backbone and a carbohydrate-rich head group. GSLs populate lipid rafts of the cell membrane of eukaryotic cells, and serve important cellular functions including ...
Alex E. Ryckman   +2 more
semanticscholar   +1 more source

Lyso-glycosphingolipids: presence and consequences

open access: yesEssays in Biochemistry, 2020
Lyso-glycosphingolipids are generated in excess in glycosphingolipid storage disorders. In the course of these pathologies glycosylated sphingolipid species accumulate within lysosomes due to flaws in the respective lipid degrading machinery. Deacylation
M. van Eijk   +3 more
semanticscholar   +1 more source

Targeting glycosphingolipids for cancer immunotherapy

open access: yesFEBS Letters, 2020
Aberrant expression of glycosphingolipids (GSLs) is a unique feature of cancer and stromal cells in tumor microenvironments. Although the impact of GSLs on tumor progression remains largely unclear, anticancer immunotherapies directed against GSLs are ...
John Yu   +4 more
semanticscholar   +1 more source

Characterization of glycosphingolipids by direct inlet chemical ionization mass spectrometry

open access: yesJournal of Lipid Research, 1980
Permethylated derivatives of cerebrosides and ceramide di-, tri-, tetra-, and penta-hexosides were analyzed by the direct inlet ammonia chemical ionization (CI) mass spectrometry. In the CI mass spectra, the fragment ions produced by the loss of methanol
T Ariga   +4 more
doaj   +1 more source

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