Results 71 to 80 of about 25,840 (267)

Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)

ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang, Chunlan Deng, Xiaogang Guo, Hui Yan   +3 more
wiley   +1 more source

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

The FEBS Journal, EarlyView.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher, Pavel Dobeš, Jan Komárek, Lukáš Faltinek, Marek Korsák, Petra Sýkorová, Josef Houser, Michaela Wimmerová   +7 more
wiley   +1 more source

Transcriptional Regulation of T-Cell Lipid Metabolism: Implications for Plasma Membrane Lipid Rafts and T-Cell Function

Frontiers in Immunology, 2017
It is well established that cholesterol and glycosphingolipids are enriched in the plasma membrane (PM) and form signaling platforms called lipid rafts, essential for T-cell activation and function.
George A. Robinson, Kirsty E. Waddington, Kirsty E. Waddington, Ines Pineda-Torra, Elizabeth C. Jury   +4 more
doaj   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

WRKY27‐RAP2.7 Regulatory Module Promotes Cold Tolerance via Modulation of Lignin Biosynthesis and Redox Homeostasis by Regulating Cinnamyl Alcohol Dehydrogenase 7 and Glutathione S‐Transferase F6

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cold stress adversely affects plant growth and development, significantly limiting fruit yield and quality in citrus. Ichang papeda (Citrus ichangensis), a cold‐tolerant citrus species, serves as a valuable genetic resource for studying cold adaptation, yet the key genes and their modes of action underlying the cold stress response remain ...
Jing Qu, Peng Xiao, Yilei Wang, Tian Fang, Haowei Chen, Chunlong Li, Ji‐Hong Liu   +6 more
wiley   +1 more source

The Enigmatic Role of GBA2 in Controlling Locomotor Function

Frontiers in Molecular Neuroscience, 2017
The non-lysosomal glucosylceramidase GBA2 catalyzes the hydrolysis of glucosylceramide to glucose and ceramide. Loss of GBA2 function results in accumulation of glucosylceramide.
Marina A. Woeste, Dagmar Wachten, Dagmar Wachten   +2 more
doaj   +1 more source

β-glycosphingolipids ameliorated non-alcoholic steatohepatitis in the Psammomys obesus model

Journal of Inflammation Research, 2014
Liver steatosis is a common characteristic of obesity and type 2 diabetes, and fatty liver disease is increasingly recognized as a major health burden. Accumulating evidence suggests that β-glycosphingolipids play an important role in insulin sensitivity
E. Zigmond, Oshrat E Tayer-Shifman, G. Lalazar, A. Ben Ya’acov, S. Weksler-Zangen, D. Shasha, M. Sklair-Levy, L. Zolotarov, Z. Shalev, R. Kalman, E. Ziv, I. Raz, Y. Ilan   +12 more
semanticscholar   +1 more source

glycosphingolipid

, 2014
Citation: 'glycosphingolipid' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02662 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Glycosphingolipids of human thyroid

Lipids, 1974
AbstractGlycosphingolipids were isolated from total lipids of female and male human thyroids by alkaline hydrolysis, silicic acid, diethylaminoethyl‐celluose and thin layer chromatography and analyzed by gas liquid chromatography. On the basis of their mobility in two dimensions on thin layer chromatography, IR analysis, and of sugar molar ratio, four ...
Karli, J.N., Levis, G.M.
openaire   +3 more sources

Nephropathy in Fabry disease: possibilities for the radical improvement of prognosis for orphan diseases

Терапевтический архив, 2013
The paper discusses the specific features of the diagnosis and treatment of kidney involvement in patients with Fabry disease.
V V Fomin, A A Pulin, N A Mukhin
doaj