Results 131 to 140 of about 6,124,437 (230)

Associations between cognitive reserve, glymphatic function and cognitive function in mild cognitive impairment

Frontiers in Aging Neuroscience
ObjectiveTo evaluate the association between cognitive reserve (CR) and glymphatic function in mild cognitive impairment (MCI), and to examine whether the relationship between CR and cognition is mediated by glymphatic function.Methods113 MCI individuals
Liang Zhou, Liang Zhou, Minjia Ma, Wenxia Yang, Jingxian Shi, Sibin Liu, Sibin Liu, Wenze Wu, Wenze Wu, Jing Zhang   +9 more
doaj   +1 more source

Water and wisdom: Hydration as a defence against dementia

Experimental Physiology, EarlyView.
David C. Byfield, Damian M. Bailey
wiley   +1 more source

Glymphatic system: a self-purification circulation in brain

Frontiers in Cellular Neuroscience
The glymphatic system theory introduces a new perspective on fluid flow and homeostasis in the brain. Here, cerebrospinal fluid and interstitial fluid (CSF-ISF) moves from the perivascular spaces (PVS) of arteries to those of veins for drainage ...
Siying Chen, Siying Chen, Huijing Wang, Lini Zhang, Yingying Xi, Yiying Lu, Kailin Yu, Yujie Zhu, Izmailova Regina, Yong Bi, Fang Tong, Fang Tong   +11 more
doaj   +1 more source

Ventricular and Choroid Plexus Morphological Alterations and Their Associations With Peripheral Biomarkers in Behavioral Variant Frontotemporal Dementia

Brain and Behavior, Volume 16, Issue 11, November 2026.
ABSTRACT Background Frontotemporal dementia (FTD) is a neurodegenerative disorder and a major cause of early‐onset dementia. Alterations in ventricular and choroid plexus volumes have been reported in several neurodegenerative diseases. The morphological alterations of the ventricular system and choroid plexus in behavioral variant frontotemporal ...
Ailing Yue, Qianqian He, Hua Lu, Yufei Chen, Jiahui Hou, Yuxuan Xu, Liyong Wu, Min Chu   +7 more
wiley   +1 more source

Exosomes in Traumatic Brain Injury: From Secondary Injury Mechanisms to Cell‐Free Neurorepair

Brain and Behavior, Volume 16, Issue 11, November 2026.
A bibliometric map of exosome research in traumatic brain injury. Analysis of 609 publications from the Web of Science Core Collection and Scopus (2012‐2025; search completed October 24, 2025) maps the evolution of research emphasis from secondary injury and neuroinflammation toward stem‐cell‐derived exosomes, engineered vesicles, drug delivery and ...
Guiling Gu, Hailiang Tang, Haixia Fan
wiley   +1 more source

Reply to: The Physical Foundation of CSF‐IVIM

Magnetic Resonance in Medicine, Volume 97, Issue 1, Page 6-7, January 2027.
Yoshitaka Bito, Tomohiro Otani, Shigeki Yamada, Yoshiyuki Watanabe, Shigeo Wada   +4 more
wiley   +1 more source

Reduced Coupling Between Blood‐Oxygen‐Level‐Dependent Signal and Cerebrospinal Fluid Flow in Obsessive‐Compulsive Disorder

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Patients with OCD exhibited weaker BOLD–CSF coupling and negative derivative BOLD–CSF coupling strength than HC, both globally and regionally within the goal‐directed and habitual systems. OCD patients also showed a longer time lag of global BOLD–CSF coupling.
Jinqi Liu, Ziyun Xu, Wanting Liu, Carol A. Seger, Ziwen Peng, Gangqiang Hou   +5 more
wiley   +1 more source

Pan‐Adrenergic Inhibition Alleviates Post‐Hemorrhagic Hydrocephalus by Attenuating Neutrophil Extracellular Traps‐Mediated Glymphatic Dysfunction

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Intraventricular hemorrhage induces an adrenergic response that activates PI3K/AKT/mTOR signaling and promotes neutrophil extracellular trap (NET) formation, impairing glymphatic clearance and aggravating post‐hemorrhagic hydrocephalus (PHH). Pan‐adrenergic inhibition after hemorrhage reduced PI3K/AKT/mTOR activation and NET formation, preserved AQP4 ...
Yijian Yang, Yanjie Zhou, Qian Ouyang, Hanati Nuerlanbieke, Yexin Yuan, Junqiang Wang, Kaiyue Wang, Peng Long, Yifeng Chen, Zhikun Liu, Jun Huang, Zhiping Zhang, Zhangjie Su, Xia Wang, Gelei Xiao   +14 more
wiley   +1 more source

From Mechanical Perturbation to Pathological Locking: Temporal–Mechanical Evolution of the Postsynaptic Density After Traumatic Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
The postsynaptic density (PSD) may convert traumatic mechanical loading into persistent synaptic dysfunction. This review proposes a temporal–mechanical model in which PSD injury progresses from hyperacute mechanical deconstruction (Phase I) through an acute‐to‐subacute metabolic–mechanical crisis (Phase II) to chronic low‐dynamic pathological locking (
Yibin Jia, Zixuan Cao, Hanjiang Xue, Zhebin Feng, Zhiguo Ma, Zhicheng Tian, Xin Li, Peng Luo   +7 more
wiley   +1 more source

Association of Perivascular Space Volume in Basal Ganglia Subfields With Cognitive Impairment in Cerebral Small Vessel Disease

Human Brain Mapping, Volume 47, Issue 16, November 2026.
Schematic overview of the study design and main findings. This cross‐sectional single‐center study demonstrates that enlarged PVS volume in the basal ganglia (BG) subfields, particularly the caudate and putamen, is associated with worse cognitive function in CSVD.
Lulu Ai, Zhiwei Li, Chaojuan Huang, Xia Zhou, Qiaoqiao Xu, Xiaoqun Zhu, Zhongwu Sun   +6 more
wiley   +1 more source