Results 31 to 40 of about 6,124,437 (230)

Glymphatic system function in patients with newly diagnosed focal epilepsy [PDF]

Brain and Behavior, 2022
Abstract Introduction The aim of this study was to analyze the glymphatic system function and its relationship with clinical characteristics, global diffusion tensor imaging (DTI) parameters, and global structural connectivity in treatment‐naïve patients with newly diagnosed focal epilepsy.
Dong Ah Lee, Bong Soo Park, Junghae Ko, Si hyung Park, Jin‐Han Park, Il Hwan Kim, Yoo Jin Lee, Kang Min Park   +7 more
openaire   +2 more sources

A clinical primer for the glymphatic system

, 2021
The complex and dynamic system of fluid flow through the perivascular and interstitial spaces of the CNS has new-found implications for neurological diseases.
Eltanahy, Ahmed, Perry, Avital, Elder, Benjamin D., Rabinstein, Alejandro A., Graffeo, Christopher S., Lundgaard, Iben, Carlstrom, Lucas P., Morris, Jonathan M., Meyer, Fredric B., Burns, Terry C., Burns, Terry C.,, Morris, Jonathan M.,, Perry, Avital,, Lundgaard, Iben,, Carlstrom, Lucas P.,, Meyer, Fredric B.,, Elder, Benjamin D.,, Rabinstein, Alejandro A.,, Eltanahy, Ahmed,, Graffeo, Christopher S.,, Lund University., Avital Perry, Alejandro A Rabinstein, Benjamin D Elder, Jonathan M Morris, Fredric B Meyer, Ahmed Eltanahy, Iben Lundgaard, Christopher S Graffeo, Lucas P Carlstrom, Terry C Burns   +30 more
core   +1 more source

SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline

, 2022
Repository for original code used in research article    "SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline"
Marko Rosenholm (13814824)
core   +1 more source

Glymphatic Function as a Prognostic Biomarker in Prolonged Disorders of Consciousness. [PDF]

CNS Neurosci Ther
ABSTRACTObjectiveThe glymphatic system is a major waste clearance system in the central nervous system. We aim to investigate the glymphatic function and its prognostic values in patients with prolonged disorders of consciousness (pDoC).MethodsWe conducted a prospective and explorative cohort study including 40 patients with pDoC and 20 healthy ...
Wu DW, Song CG, Chen R, Zhao JJ, Zhang YC, Wang X, Sun ZQ, Kang XG, Gao Q, Jiang W.   +9 more
europepmc   +3 more sources

Cisterna Magna Injection in Rats to Study Glymphatic Function [PDF]

, 2019
The recently discovered glymphatic system, which supports brain-wide clearance of metabolic waste, has become the subject of intense research within the past few years. Its nomenclature arose due to its functionally analogous nature to the lymphatic system in combination with glial cells that are part of its anatomical boundaries.
Ramos, Marta, Burdon Bechet, Nicholas, Battistella, Roberta, Pavan, Chiara, Xavier, Anna L.R., Nedergaard, Maiken, Lundgaard, Iben   +6 more
openaire   +3 more sources

Attenuation of cerebral edema facilitates recovery of glymphatic system function after status epilepticus

JCI Insight, 2021
Status epilepticus (SE) is a neurological emergency usually accompanied by acute cerebral edema and long-term cognitive impairment, and is characterized by neurodegeneration and aberrant hyperphosphorylated tau protein (p-tau) aggregation.
Kewei Liu, Juan Zhu, Yuan Chang, Zhenzhou Lin, Zhu Shi, Xing Li, Xing Chen, Chuman Lin, Suyue Pan, Kaibin Huang   +9 more
doaj   +1 more source

Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function [PDF]

, 2018
Prolonged intake of excessive amounts of ethanol is known to have adverse effects on the central nervous system (CNS). Here we investigated the effects of acute and chronic ethanol exposure and withdrawal from chronic ethanol exposure on glymphatic ...
Hanna Sophia Vinitsky, Wang, Wei, Nanhong Lou, Reeves, Benjamin Cameron, Benjamin Cameron Reeves, Eberhardt, Allison, Iben Lundgaard, Rashad Hussain, Sisi Peng, Hussain, Rashad, Lundgaard, Iben, Maiken Nedergaard, Allison Eberhardt, Peng, Sisi, Wei Wang, Nedergaard, Maiken, Lou, Nanhong, Vinitsky, Hanna Sophia   +17 more
core   +1 more source

Glymphatic Dysfunction and Related Brain Structure Changes in Major Depressive Disorder: Effects of Glymphatic Function in Mediating Neuroinflammation. [PDF]

Psychiatry Investig
Objective The glymphatic system, responsible for cerebrospinal fluid flow and waste clearance, is increasingly implicated in the pathophysiology of major depressive disorder (MDD) through its influence on neuroinflammation. This study investigated the association between glymphatic dysfunction, systemic inflammation, and brain volume changes in ...
Shin D, Han KM, Kang Y, Auer DP, Tae WS, Ham BJ.   +5 more
europepmc   +4 more sources

Glymphatic System Function in Relation to Anesthesia and Sleep States

Anesthesia & Analgesia, 2019
The brain is one of the most metabolically active organs in the body. The brain’s high energy demand associated with wakefulness persists during rapid eye movement sleep, and even during non–rapid eye movement sleep, cerebral oxygen consumption is only reduced by 20%.
Helene, Benveniste, Paul M, Heerdt, Manuel, Fontes, Douglas L, Rothman, Nora D, Volkow   +4 more
openaire   +3 more sources

Wasteosomes (corpora amylacea) as a hallmark of chronic glymphatic insufficiency [PDF]

, 2023
In different organs and tissues, the lymphatic system serves as a drainage system for interstitial fluid and is useful for removing substances that would otherwise accumulate in the interstitium.
Valle i Macià, Jaume del, Molina Porcel, Laura, Vilaplana i Hortensi, Jordi, Riba Baqués, Marta, Pelegrí, Carme   +4 more
core   +1 more source