Results 61 to 70 of about 4,592 (135)

Activation of the G Protein-Coupled Estrogen Receptor Elicits Store Calcium Release and Phosphorylation of the Mu-Opioid Receptors in the Human Neuroblastoma SH-SY5Y Cells

Frontiers in Neuroscience, 2019
Estrogens exert extensive influences on the nervous system besides their well-known roles in regulation of reproduction and metabolism. Estrogens act via the nuclear receptor ERα and ERβ to regulate gene transcription (classical genomic effects).
Xiaowei Ding, Xiaowei Ding, Ting Gao, Po Gao, Youqiang Meng, Yi Zheng, Li Dong, Ping Luo, Guohua Zhang, Xueyin Shi, Weifang Rong, Weifang Rong   +11 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

G protein-coupled estrogen receptor expression in postnatal developing mouse retina

Frontiers in Ophthalmology
IntroductionEstrogen has emerged as a multifaceted signaling molecule in the retina, playing an important role in neural development and providing neuroprotection in adults.
Wendy L. Piñon-Teal, Judith Mosinger Ogilvie, Judith Mosinger Ogilvie   +2 more
doaj   +1 more source

Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer

BMC Cancer, 2012
Background G-protein-coupled estrogen receptor (GPER/GPR30) was reported to bind 17β-estradiol (E2), tamoxifen, and ICI 182,780 (fulvestrant) and promotes activation of epidermal growth factor receptor (EGFR)-mediated signaling in breast, endometrial and
Jala Venkatakrishna Rao, Radde Brandie N, Haribabu Bodduluri, Klinge Carolyn M   +3 more
doaj   +1 more source

A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models

Disease Models & Mechanisms, 2015
Estrogens regulate numerous pathophysiological processes, mainly by binding to and activating estrogen receptor (ER)α and ERβ. Increasing amounts of evidence have recently demonstrated that G-protein coupled receptor 30 (GPR30; also known as GPER) is ...
Rosamaria Lappano, Camillo Rosano, Assunta Pisano, Maria Francesca Santolla, Ernestina Marianna De Francesco, Paola De Marco, Vincenza Dolce, Marco Ponassi, Lamberto Felli, Grazia Cafeo, Franz Heinrich Kohnke, Sergio Abonante, Marcello Maggiolini   +12 more
doaj   +1 more source

Patients’ and Caregivers’ Experiences Navigating the Burden of Atopic Dermatitis in Argentina

Medicina
Background and Objectives: Little is known about patients’ and caregivers’ experiences with atopic dermatitis (AD) in Argentina, so a survey was administered to learn more.
Korey Capozza, Michelle Tu, Alan Schwartz, Jodi L. Johnson, Mónica Ladner   +4 more
doaj   +1 more source

Sleep and Methylation of Estrogen Receptor Genes, ESR1 and GPER, in Healthy Middle-Aged and Older Women: Findings from the Women 40+ Healthy Aging Study

Nature and Science of Sleep, 2020
Elena S Gardini,1,2 Serena Fiacco,1,2 Laura Mernone,1,2 Ulrike Ehlert1,2 1Clinical Psychology and Psychotherapy, University of Zurich, Zurich, Switzerland; 2University Research Priority Program (URPP) Dynamics of Healthy Aging, University of Zurich ...
Gardini ES, Fiacco S, Mernone L, Ehlert U   +3 more
doaj  

YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia

iScience
Summary: Benign prostatic hyperplasia (BPH) occurs when there is an imbalance between the proliferation and death of prostate cells, which is regulated tightly by estrogen signaling.
Zhifu Liu, Senmao Li, Shengbin Chen, Jindong Sheng, Zheng Li, Tianjing Lv, Wei Yu, Yu Fan, Jinlong Wang, Wei Liu, Shuai Hu, Jie Jin   +11 more
doaj   +1 more source

The double-edged sword effect of estrogen in kidney disease and its precision modulation. [PDF]

Front Endocrinol (Lausanne)
Zhang J, Lyu J, Deng M, Han J, Wang Q, Song J, Zheng R, Bai Z.   +7 more
europepmc   +1 more source

miR-16-5p mediates E2-induced cell proliferation and EMT in benign prostate hyperplasia. [PDF]

Sci Rep
Kim JE, An L, Xu Y, Park E, Lee HJ.
europepmc   +1 more source