Results 61 to 70 of about 10,884 (213)
PLOS ONE, 2015 Estradiol increases cell proliferation in the dentate gyrus of the female rodent but it is not known whether the G protein-coupled estrogen receptor (GPER), a membrane receptor, is involved in this process, nor whether there are regional differences in estradiol's effects on cell proliferation. Thus, we investigated whether estradiol exerts its effects
Paula Duarte-Guterman +3 more
openaire +4 more sources
Frontiers in Cell and Developmental BiologyTriple-negative breast cancer (TNBC) is a biologically and clinically heterogeneous disease. The G protein-coupled estrogen receptor (GPER) plays a crucial role in mediating the effect of estrogen and estrogen-like compounds in TNBC cells.
Duo Zhang +6 more
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2023 Objective In this study, a meta-analysis of the expression of G-protein-coupled estrogen receptor (GPER) in breast cancer (BC) and its role in prognosis was conducted to understand the effect of this expression on the survival and clinicopathological ...
LIU Longjiao, YAO Yufeng
doaj +1 more source
Melanoma Cells Exposed to Clomiphene Citrate Respond With Cell Cycle Arrest and Reduced Invasiveness
Journal of Applied Toxicology, EarlyView.ABSTRACT Epidemiological studies have suggested that clomiphene citrate (CC) exposure may increase the risk of malignant melanoma, but mechanisms are unknown. We investigated the effects of CC on melanoma cell line A375. Cells were treated with CC at 2, 20, 200, and 2000 ng/mL, followed by assessment of cell viability and metabolism, cell cycle ...
Thaís S. Ribeiro +8 more
wiley +1 more source
Frontiers in Endocrinology, 2023 Aldosterone is one of the most essential hormones synthesized by the adrenal gland because it regulates water and electrolyte balance. G protein–coupled estrogen receptor (GPER) is a newly discovered aldosterone receptor, which is proposed to mediate the
Xuehan Li +11 more
doaj +1 more source
Shanks-transform accelerated PML-based series expansions for the 1-D periodic 3-D Green's functions of multilayered media [PDF]
, 2008 A PerfectlyMatched Layer (PML) based formalismis proposed to derive fast converging series expansions for the 1D periodic 3D Green’s functions of layered media.
Rogier, Hendrik
core
Estradiol activates PI3K/Akt/GSK3 pathway under chronic neurodegenerative conditions triggered by perinatal asphyxia [PDF]
, 2018 Perinatal asphyxia (PA) remains as one of the most important causes of short-term mortality, psychiatric and neurological disorders in children, without an effective treatment.
Bellini, Maria Jose +3 more
core +2 more sources
Menopause and vascular endothelial health: Is it all about the oestrogen?
Experimental Physiology, EarlyView.Abstract Cardiovascular disease (CVD) is a leading cause of mortality in women, and CVD risk is accelerated during the menopause transition. This acceleration has traditionally been attributed to the hallmark decline in oestradiol with menopause. However, the menopause transition is also characterized by changes in other sex hormones that exert effects
Virginia R. Nuckols +4 more
wiley +1 more source
Mapping of Coulomb gases and sine-Gordon models to statistics of random surfaces [PDF]
, 2008 We introduce a new class of sine-Gordon models, for which interaction term is present in a region different from the domain over which quadratic part is defined.
A. D. Polyanin +9 more
core +2 more sources
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.This article systematically reviews how insulin resistance (IR) disrupts endometrial receptivity by interfering with glucose metabolism mechanisms, ultimately leading to infertility in patients with Polycystic Ovary Syndrome (PCOS). ABSTRACT Introduction Insulin resistance (IR) is one of the important pathologic bases of polycystic ovary syndrome (PCOS)
Si‐yan Huang +7 more
wiley +1 more source