Results 81 to 90 of about 10,884 (213)
Physiological Reports, Volume 14, Issue 11, June 2026.Abstract Sex differences in asthma severity have been reported; however, the specific contribution of estrogen receptor β (ERβ) remains incompletely defined. We tested the hypothesis that ERβ modulates sex‐specific physiological responses to chronic allergen exposure using C57BL/6J wild‐type (WT) and ERβ‐deficient (Esr2−/−) male and female mice ...
Carolyn Damilola Ekpruke +12 more
wiley +1 more source
Cells, 2020 The G protein-coupled estrogen receptor (GPER, formerly known as GPR30) is a seven-transmembrane receptor that mediates estrogen signals in both normal and malignant cells.
Marianna Talia +8 more
doaj +1 more source
Estrogen as a therapeutic agent: Targeting endotheliopathy and coagulopathy in trauma
Transfusion, Volume 66, Issue S1, Page S224-S232, May 2026.Abstract Background Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma‐induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need
Niruktha Raghavan +4 more
wiley +1 more source
Frontiers in Pharmacology, 2015 Aldosterone promotes non-genomic effects in endothelial and vascular smooth muscle cells via activation of mineralocorticoid receptors (MR) and G protein-coupled estrogen receptors (GPER).
Nathanne Santos Ferreira +7 more
doaj +1 more source
Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.Abstract INTRODUCTION Sleep and circadian disturbances are early Alzheimer's disease (AD) features, yet mechanisms linking amyloid pathology, neuroinflammation, and sex differences remain unclear. METHODS We longitudinally assessed sleep, circadian rhythms, and cognition in female and male hAPPSAA knock‐in and control mice from 2 to 19 months using ...
Teresa Macheda +18 more
wiley +1 more source
Neuroendocrinology, 2016 Nitric oxide is produced in the brain by the neuronal nitric oxide synthase (nNOS) and carries out a wide range of functions by acting as a neurotransmitter-like molecule. Gonadal hormones are involved in the regulation of the brain nitrergic system. We have previously demonstrated that estradiol, via classical estrogen receptors (ERs), regulates NOS ...
Grassi, Daniela +5 more
openaire +3 more sources
GPER Mediates Functional Endothelial Aging in Renal Arteries [PDF]
Pharmacology, 2017 Aging is associated with impaired renal artery function, which is partly characterized by arterial stiffening and a reduced vasodilatory capacity due to excessive generation of reactive oxygen species by NADPH oxidases (Nox). The abundance and activity of Nox depends on basal activity of the heptahelical transmembrane receptor GPER; however, whether ...
Meyer, Matthias R +3 more
openaire +4 more sources
G Protein-Coupled Estrogen Receptor: A Potential Therapeutic Target in Cancer
Frontiers in Endocrinology, 2019 The G protein-coupled estrogen receptor (GPER) is a seven-transmembrane-domain receptor that mediates non-genomic estrogen related signaling. After ligand activation, GPER triggers multiple downstream pathways that exert diverse biological effects on the
Shen Xu +5 more
doaj +1 more source
NMR and $\mu^{+}$SR detection of unconventional spin dynamics in Er(trensal) and Dy(trensal) molecular magnets [PDF]
, 2019 Measurements of proton Nuclear Magnetic Resonance (1H NMR) spectra and relaxation and of Muon Spin Relaxation ($\mu^{+}$SR) have been performed as a function of temperature and external magnetic field on two isostructural lanthanide complexes, Er(trensal)
Adelnia, F. +9 more
core +3 more sources
Canned Foods: Evolution, Benefits, and Health Implications of Modern Packaging
Food Safety and Health, Volume 4, Issue 2, Page 310-326, April 2026.This graphical abstract presents a concise visual overview of canned food technology, highlighting its historical evolution, key benefits, and associated health risks. It integrates timelines, icons, and summary points to clearly communicate advancements in preservation, consumer advantages, and potential safety concerns in a single schematic ...
Shaswati Rout +3 more
wiley +1 more source