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Inhibitory effects of grape seed extract on lipases

Nutrition, 2003
The aim of the present study was to assess the effects of grape seed extract (GSE) on the fat-metabolizing enzymes pancreatic lipase, lipoprotein lipase, and hormone-sensitive lipase in vitro and evaluate its potential application as a treatment for obesity.Crushed grape seeds were extracted in ethanol, and the extract was assayed for the measurement ...
Diego A, Moreno   +5 more
openaire   +2 more sources

Grape Seed Extract Laboratory Guidance Document

2019
Grape Seed Extract (GSE) has received acceptance almost globally as an ingredient for human consumption. It is one of the more widely used botanical extracts, due to increasing scientific findings supporting health benefits. However, it remains a specialty item relative to global commodities.
Steve Kupina   +3 more
openaire   +1 more source

Health Perspectives of Grape Seed Extract (GSE)

Asian Journal of Allied Health Sciences (AJAHS), 2020
From the last decade flavonoids have become very prominent in the studies related to grapes. It has also been outlined by the recent researches that the positive effects of the constituents derived from theresidues of grapes are due to the polyphenolic compounds. Grape Seed Extract (GSE) possess a wide spectrum of medicinal features to inhibit reaction
openaire   +1 more source

Grape seed proanthocyanidin extract attenuates oxidant injury in cardiomyocytes

Pharmacological Research, 2003
This study sought to test whether grape seed proanthocyanidin extract (GSPE) attenuates exogenous and endogenous oxidant stress induced in chick cardiomyocytes and whether this cytoprotection is mediated by PKC activation, mito K(ATP) channel opening, NO production, oxidant scavenging, or iron chelating effects. Cells were exposed to hydrogen peroxide (
Zuo-Hui, Shao   +10 more
openaire   +2 more sources

Microwave-assisted Extraction of Phenolic Compounds from Grape Seed

Natural Product Letters, 2001
A microwave-assisted extraction technique was developed to optimize the extraction of phenolic compounds from grape seeds. The microwave power (300-150W) and time of extraction (20-200s) were varied during the optimization process. The polyphenol content of the resulting extracts were measured as mg of tannic acid equivalent per gram of crude extract ...
N, Hong   +4 more
openaire   +2 more sources

Grape seed proanthocyanidin extract (GSPE) attenuates collagen-induced arthritis

Immunology Letters, 2009
To examine whether grape seed proanthocyanidin extract (GSPE) which is known to act as an antioxidant has therapeutic effect on collagen-induced arthritis (CIA) in mice, an animal model of rheumatoid arthritis. Mice were treated with an intraperitoneal injection of GSPE (10, 50, or 100 mg/kg) or saline.
Mi-La, Cho   +9 more
openaire   +2 more sources

Semi‐industrial ultrasound‐assisted extraction of grape‐seed proteins

Journal of the Science of Food and Agriculture
AbstractBACKGROUNDTo manage industrial waste in accordance with the circular bioeconomy concept it is sometimes necessary to handle grape seeds, an abundant by‐product of the wine‐making process. This study presents a process based on ultrasound technology for the extraction of grape‐seed proteins, due to their nutritional and techno‐functional ...
Chaji S.   +5 more
openaire   +3 more sources

Safety evaluation of proanthocyanidin-rich extract from grape seeds

Food and Chemical Toxicology, 2002
Proanthocyanidins, extracted from grape seeds, are widely used mainly as nutritional supplements. However, there has not been a systematic report to investigate toxicological studies on proanthocyanidins, especially in oral administration. In our studies, proanthocyanidin-rich extract from grape seeds was subjected to a series of toxicological tests to
J, Yamakoshi   +3 more
openaire   +2 more sources

Grape Seed Extract Effects in Brain After Hypobaric Hypoxia

Journal of Medicinal Food, 2013
Hypoxia induces a wide range of deleterious effects at the cellular level due to an increased production of reactive oxygen species (ROS). Polyphenols from grape seeds, which are potent antioxidants might protect the brain against oxidative stress produced by hypobaric hypoxia. The brain effects of three doses of grape seed extract intraperitoneally (i.
Adriana, Muresan   +4 more
openaire   +2 more sources

Adulteration of Grape Seed Extract (Vitis vinifera)

2016
The goal of this bulletin is to provide timely information and/or updates on issues of adulteration of grape seed extract (GSE†) to the international herbal products industry and extended natural products community in general. It is intended to present the available data on the occurrence of adulteration, the market situation, and consequences for the ...
Steve Kupina, Stefan Gafner
openaire   +1 more source

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